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The map label for this gene is dmsB [H]

Identifier: 157371163

GI number: 157371163

Start: 3219255

End: 3219809

Strand: Direct

Name: dmsB [H]

Synonym: Spro_2923

Alternate gene names: 157371163

Gene position: 3219255-3219809 (Clockwise)

Preceding gene: 157371162

Following gene: 157371164

Centisome position: 59.08

GC content: 54.59

Gene sequence:

>555_bases
ATGGTCAGACAATATGGTTTCTTGGTTGATATGCGTGGCTGTTACGGCTGTAAAACCTGCTCAATGGCCTGCAAATCCGA
AAATGCCACTCCGGCGGGCGTGCTGTGGCGCCGGGTCAGGGAATTTAGCTTTGACGATCCTAACGCGATGGCGTTTATCT
CGATGTCCTGCAATCACTGTGACGATCCGCAGTGTATGGAAGTCTGCCCCGCCGATACCTACAGTAAACGCCCGGACGGC
ATCGTGGTGCAGGATCACGACAAATGCATTGGTTGCCGGATGTGCATTATGGCTTGTCCCTACAATGCGCCGGTATTCGA
CCCGGTCGAAGGGAAAACCAGCAAGTGCAACCTGTGTGCCGAACGGCTGGATGAGGGGTTGCAACCCCGTTGTGTCGAGT
CCTGCCCGGCCGGAGTGCTGCAGTTTGGTGATATAGACGTGCTGCGCGTGCAGTACTCCGCTGACTTAACGCGCATCGAA
ACCCGTTACTCACTGCCGAACCATCAAATCAGCCATCCCAATATCGTGATTATTCCCGCCGGTGATAAGGAATAG

Upstream 100 bases:

>100_bases
GGGGCAGCAGCAGCCATGTGACTAACGATCATGTGGAGGTTCTGGGCACCGGCCATTGTTGTAACAGCACCCTGGTTGAC
GTTAGAGCGGAGGCATAATC

Downstream 100 bases:

>100_bases
ATGCCATGTCTGAATATGAACTTCCCCTGGTCTTTTTTACCGTATTTTGTCAGTGGGCGGTGGGCACGATTGTGGCCATC
ACAATACTAATCCTCGCCCA

Product: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MVRQYGFLVDMRGCYGCKTCSMACKSENATPAGVLWRRVREFSFDDPNAMAFISMSCNHCDDPQCMEVCPADTYSKRPDG
IVVQDHDKCIGCRMCIMACPYNAPVFDPVEGKTSKCNLCAERLDEGLQPRCVESCPAGVLQFGDIDVLRVQYSADLTRIE
TRYSLPNHQISHPNIVIIPAGDKE

Sequences:

>Translated_184_residues
MVRQYGFLVDMRGCYGCKTCSMACKSENATPAGVLWRRVREFSFDDPNAMAFISMSCNHCDDPQCMEVCPADTYSKRPDG
IVVQDHDKCIGCRMCIMACPYNAPVFDPVEGKTSKCNLCAERLDEGLQPRCVESCPAGVLQFGDIDVLRVQYSADLTRIE
TRYSLPNHQISHPNIVIIPAGDKE
>Mature_184_residues
MVRQYGFLVDMRGCYGCKTCSMACKSENATPAGVLWRRVREFSFDDPNAMAFISMSCNHCDDPQCMEVCPADTYSKRPDG
IVVQDHDKCIGCRMCIMACPYNAPVFDPVEGKTSKCNLCAERLDEGLQPRCVESCPAGVLQFGDIDVLRVQYSADLTRIE
TRYSLPNHQISHPNIVIIPAGDKE

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=192, Percent_Identity=44.7916666666667, Blast_Score=160, Evalue=4e-41,
Organism=Escherichia coli, GI1787872, Length=192, Percent_Identity=44.2708333333333, Blast_Score=159, Evalue=8e-41,
Organism=Escherichia coli, GI226510944, Length=167, Percent_Identity=34.7305389221557, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789370, Length=195, Percent_Identity=34.8717948717949, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790326, Length=183, Percent_Identity=29.5081967213115, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI2367345, Length=169, Percent_Identity=36.6863905325444, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1787749, Length=155, Percent_Identity=31.6129032258064, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787963, Length=159, Percent_Identity=30.8176100628931, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787740, Length=112, Percent_Identity=35.7142857142857, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787478, Length=95, Percent_Identity=38.9473684210526, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI2367245, Length=152, Percent_Identity=32.2368421052632, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI87082179, Length=144, Percent_Identity=32.6388888888889, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1788811, Length=178, Percent_Identity=30.3370786516854, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082180, Length=132, Percent_Identity=31.0606060606061, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1789067, Length=170, Percent_Identity=30.5882352941176, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 20516; Mature: 20516

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
13.0 %Cys+Met (Translated Protein)
8.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
13.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRQYGFLVDMRGCYGCKTCSMACKSENATPAGVLWRRVREFSFDDPNAMAFISMSCNHC
CCCCCCEEEECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
DDPQCMEVCPADTYSKRPDGIVVQDHDKCIGCRMCIMACPYNAPVFDPVEGKTSKCNLCA
CCCHHHHHCCCCCCCCCCCCEEEECCCCHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHH
ERLDEGLQPRCVESCPAGVLQFGDIDVLRVQYSADLTRIETRYSLPNHQISHPNIVIIPA
HHHCCCCCCHHHHHCCCCEEEECCEEEEEEEECCCCEEEEEEECCCCCCCCCCCEEEEEC
GDKE
CCCC
>Mature Secondary Structure
MVRQYGFLVDMRGCYGCKTCSMACKSENATPAGVLWRRVREFSFDDPNAMAFISMSCNHC
CCCCCCEEEECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
DDPQCMEVCPADTYSKRPDGIVVQDHDKCIGCRMCIMACPYNAPVFDPVEGKTSKCNLCA
CCCHHHHHCCCCCCCCCCCCEEEECCCCHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHH
ERLDEGLQPRCVESCPAGVLQFGDIDVLRVQYSADLTRIETRYSLPNHQISHPNIVIIPA
HHHCCCCCCHHHHHCCCCEEEECCEEEEEEEECCCCEEEEEEECCCCCCCCCCCEEEEEC
GDKE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]