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The map label for this gene is narL [H]

Identifier: 157371140

GI number: 157371140

Start: 3187472

End: 3188122

Strand: Direct

Name: narL [H]

Synonym: Spro_2900

Alternate gene names: 157371140

Gene position: 3187472-3188122 (Clockwise)

Preceding gene: 157371139

Following gene: 157371142

Centisome position: 58.5

GC content: 57.14

Gene sequence:

>651_bases
ATGACCACCGAAACTGCCGCCACTATTTTATTGATTGATGACCACCCGATGCTGCGCAATGGCGTAAAACAGCTCATCGG
TATGGACTCCCGCCTGCAGGTGATCGCTGAAGCCGGCAACGGCGAACAGGGTGTCGCACTGGCCGAAGAGCATGATCCGG
ATCTGATCCTGCTCGATCTGAACATGCCGGGCATCAATGGCCTGGAGACGCTGGATCGCCTGCGCATGACTGCGCTCTCT
GGGCGCATTGTGGTGTTTAGCGTGTCTAATCACGAGGATGACGTAGTCAGCGCGCTAAAACGCGGTGCCGACGGCTATCT
GCTGAAGGATATGGAGCCAGAGGAGTTGCTGAAAGCCCTGCATCAGGCGGCGGCCGGTCAGATGGTGTTAAGCGAGGCGT
TGACGCCGATCCTGGCGGCCAGCCTGCGTGAGAACCGCCCCAGCGCCGAACGCGATATCCAGCAGTTGACGCCACGTGAG
CGTGACATTCTCAAACTGATCGCCCAGGGTCTGCCGAACAAGATGATCGCCCGTAAGCTGACCATCACCGAAAGCACCGT
CAAGGTGCACGTCAAACACCTGTTGAAAAAAATGAAGCTGAAATCGCGCGTTGAAGCAGCCGTCTGGGTACTGCAGGGAA
AAAACGGTTAA

Upstream 100 bases:

>100_bases
TGCACGGCCGCTGCGAGATTTTACCCCGCAGCGGCGGCGGCACTGAGGTCCGGGTGGTATTTAAACCGGACAACCACGCC
ATCGACTAATGGGAGAAACC

Downstream 100 bases:

>100_bases
TCACTGCCGTTCAACGGCCCGGTTTCTGCCGGGATAGTCGGTGGTTGCAGTACTTTTGCCGGTGGCAGCCCCTGCTCTAT
TTCAGATGAAACGGTCAAAG

Product: transcriptional regulator NarL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MTTETAATILLIDDHPMLRNGVKQLIGMDSRLQVIAEAGNGEQGVALAEEHDPDLILLDLNMPGINGLETLDRLRMTALS
GRIVVFSVSNHEDDVVSALKRGADGYLLKDMEPEELLKALHQAAAGQMVLSEALTPILAASLRENRPSAERDIQQLTPRE
RDILKLIAQGLPNKMIARKLTITESTVKVHVKHLLKKMKLKSRVEAAVWVLQGKNG

Sequences:

>Translated_216_residues
MTTETAATILLIDDHPMLRNGVKQLIGMDSRLQVIAEAGNGEQGVALAEEHDPDLILLDLNMPGINGLETLDRLRMTALS
GRIVVFSVSNHEDDVVSALKRGADGYLLKDMEPEELLKALHQAAAGQMVLSEALTPILAASLRENRPSAERDIQQLTPRE
RDILKLIAQGLPNKMIARKLTITESTVKVHVKHLLKKMKLKSRVEAAVWVLQGKNG
>Mature_215_residues
TTETAATILLIDDHPMLRNGVKQLIGMDSRLQVIAEAGNGEQGVALAEEHDPDLILLDLNMPGINGLETLDRLRMTALSG
RIVVFSVSNHEDDVVSALKRGADGYLLKDMEPEELLKALHQAAAGQMVLSEALTPILAASLRENRPSAERDIQQLTPRER
DILKLIAQGLPNKMIARKLTITESTVKVHVKHLLKKMKLKSRVEAAVWVLQGKNG

Specific function: This protein activates the expression of the nitrate reductase (narGHJI) and formate dehydrogenase-N (fdnGHI) operons and represses the transcription of the fumarate reductase (frdABCD) operon in response to a nitrate/nitrite induction signal transmitted

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787473, Length=212, Percent_Identity=81.6037735849057, Blast_Score=307, Evalue=4e-85,
Organism=Escherichia coli, GI1788521, Length=214, Percent_Identity=44.392523364486, Blast_Score=180, Evalue=8e-47,
Organism=Escherichia coli, GI1790102, Length=206, Percent_Identity=35.4368932038835, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788222, Length=197, Percent_Identity=26.9035532994924, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=25.1207729468599, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=25.5, Blast_Score=84, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23715; Mature: 23584

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTETAATILLIDDHPMLRNGVKQLIGMDSRLQVIAEAGNGEQGVALAEEHDPDLILLDL
CCCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHEEECCCCCCCCEEECCCCCCEEEEEC
NMPGINGLETLDRLRMTALSGRIVVFSVSNHEDDVVSALKRGADGYLLKDMEPEELLKAL
CCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHCCCCCCEECCCCHHHHHHHH
HQAAAGQMVLSEALTPILAASLRENRPSAERDIQQLTPRERDILKLIAQGLPNKMIARKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHH
TITESTVKVHVKHLLKKMKLKSRVEAAVWVLQGKNG
HCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
>Mature Secondary Structure 
TTETAATILLIDDHPMLRNGVKQLIGMDSRLQVIAEAGNGEQGVALAEEHDPDLILLDL
CCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHEEECCCCCCCCEEECCCCCCEEEEEC
NMPGINGLETLDRLRMTALSGRIVVFSVSNHEDDVVSALKRGADGYLLKDMEPEELLKAL
CCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHCCCCCCEECCCCHHHHHHHH
HQAAAGQMVLSEALTPILAASLRENRPSAERDIQQLTPRERDILKLIAQGLPNKMIARKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHH
TITESTVKVHVKHLLKKMKLKSRVEAAVWVLQGKNG
HCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]