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The map label for this gene is astC [H]

Identifier: 157371084

GI number: 157371084

Start: 3120979

End: 3122193

Strand: Reverse

Name: astC [H]

Synonym: Spro_2844

Alternate gene names: 157371084

Gene position: 3122193-3120979 (Counterclockwise)

Preceding gene: 157371091

Following gene: 157371083

Centisome position: 57.3

GC content: 59.75

Gene sequence:

>1215_bases
ATGGAACAGCCAATCGCAGTTACCCGCCAGTCTTTCGACGACTGGATGGTCCCGGTTTACGCCCCCGCTGATTTTATTCT
GGTACGGGGAGAAGGTTCGCAGGTCTGGGATCAACAGGGTAAGTCTTACATCGATTTTGCCGGCGGTATCGCGGTCAACG
CGTTGGGCCATGCTCACCCGGTGGTGACGGCAGCATTGGTGGAGCAGGCGGGAAAACTGTGGCATCTGGGCAACGGCTAC
ACCAATGAGCCGGTACTGCGTTTGGCCAAACAGCTGATTGACGCCACCTTTGCCGACAAGGTGTTTTTCTGTAACTCCGG
GGCGGAAGCCAACGAAGCGGCACTGAAGCTGGCACGTAAACGTGCGCTGGACCAGGGCAACAGCAGCAAGAATCAGATTG
TGGCATTTAACAACGCCTTCCACGGCCGCACGCTGTTTACCGTCTCTGCCGGCGGCCAGCCGAAGTACTCCAAAGATTTC
GCCCCGCTGCCGGGCGGTATCACCCACACGCCGTTTAACGATCTGGCGGCCGCCGCCGAAGTGATCAACGACCACACCTG
CGCAGTGATCGTCGAGCCGATTCAGGGCGAAGGCGGCGTGCTGCCGGCCGATCCGGCCTTCTTGCAGGGGCTGCGTGAGC
TGTGTGACCGCCACGACGCGGTGCTGATTTTCGATGAAGTGCAAACCGGCATGGGCCGTACCGGCGAGCTGTACGCCTAT
ACGCAATACGGCGTGGTGCCTGACGTGCTGACTACCGCGAAAGCGCTGGGTTGCGGCTTCCCAATCGGCGCCATGCTGAC
CACTGACGAACTGGCTAAAACCCTGGGCGTGGGTACCCACGGCACCACCTACGGCGGCAACCCGCTGGCGACGGCGGTAG
CGGGGGCGGTGTTCTCAATCATCAACACGCCGGAAGTGCTGGATGGGGTTAAACAACGTCACCAGTGGTTCCTCGACGGC
CTGAACAAGATTAACCAGCAATACCCGATTTTCTCTGAAATCCGCGGTGGTGGCCTGTTGATTGGCTGTCAGTTGACCCA
GGATTATGCCGGTAAAGCGAAACAGATCACCCAACTGGCCAACGAAGAGGGCGTGATTGCCCTGATCGCCGGCCCGGATG
TGGTGCGTTTCACTCCTTCGCTGATCATTCCTGAGCAGGATGTGAAAGAGGGGCTGGCGCGATTCGCGCGAGCCGTGGCG
CGGATTTGCAGCTAA

Upstream 100 bases:

>100_bases
CGAACCCACGGCGCAGTTTTTGTTGTTTTGTTACGGAACATTCGGGCTGGAGCGGCCCTTACAGTCAAAATTCAGTCTTT
GCTGAGGTTATGAGGTCATT

Downstream 100 bases:

>100_bases
CACACGGGCTGCGCCTTCACCTGCGCAGCCTGCTTAAGAAGAGGTTCGCATTATGATGATTATTCGCCCTATAGAGCGTC
GCGATTTGGCTGATTTACTG

Product: bifunctional succinylornithine transaminase/acetylornithine transaminase

Products: NA

Alternate protein names: Succinylornithine aminotransferase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MEQPIAVTRQSFDDWMVPVYAPADFILVRGEGSQVWDQQGKSYIDFAGGIAVNALGHAHPVVTAALVEQAGKLWHLGNGY
TNEPVLRLAKQLIDATFADKVFFCNSGAEANEAALKLARKRALDQGNSSKNQIVAFNNAFHGRTLFTVSAGGQPKYSKDF
APLPGGITHTPFNDLAAAAEVINDHTCAVIVEPIQGEGGVLPADPAFLQGLRELCDRHDAVLIFDEVQTGMGRTGELYAY
TQYGVVPDVLTTAKALGCGFPIGAMLTTDELAKTLGVGTHGTTYGGNPLATAVAGAVFSIINTPEVLDGVKQRHQWFLDG
LNKINQQYPIFSEIRGGGLLIGCQLTQDYAGKAKQITQLANEEGVIALIAGPDVVRFTPSLIIPEQDVKEGLARFARAVA
RICS

Sequences:

>Translated_404_residues
MEQPIAVTRQSFDDWMVPVYAPADFILVRGEGSQVWDQQGKSYIDFAGGIAVNALGHAHPVVTAALVEQAGKLWHLGNGY
TNEPVLRLAKQLIDATFADKVFFCNSGAEANEAALKLARKRALDQGNSSKNQIVAFNNAFHGRTLFTVSAGGQPKYSKDF
APLPGGITHTPFNDLAAAAEVINDHTCAVIVEPIQGEGGVLPADPAFLQGLRELCDRHDAVLIFDEVQTGMGRTGELYAY
TQYGVVPDVLTTAKALGCGFPIGAMLTTDELAKTLGVGTHGTTYGGNPLATAVAGAVFSIINTPEVLDGVKQRHQWFLDG
LNKINQQYPIFSEIRGGGLLIGCQLTQDYAGKAKQITQLANEEGVIALIAGPDVVRFTPSLIIPEQDVKEGLARFARAVA
RICS
>Mature_404_residues
MEQPIAVTRQSFDDWMVPVYAPADFILVRGEGSQVWDQQGKSYIDFAGGIAVNALGHAHPVVTAALVEQAGKLWHLGNGY
TNEPVLRLAKQLIDATFADKVFFCNSGAEANEAALKLARKRALDQGNSSKNQIVAFNNAFHGRTLFTVSAGGQPKYSKDF
APLPGGITHTPFNDLAAAAEVINDHTCAVIVEPIQGEGGVLPADPAFLQGLRELCDRHDAVLIFDEVQTGMGRTGELYAY
TQYGVVPDVLTTAKALGCGFPIGAMLTTDELAKTLGVGTHGTTYGGNPLATAVAGAVFSIINTPEVLDGVKQRHQWFLDG
LNKINQQYPIFSEIRGGGLLIGCQLTQDYAGKAKQITQLANEEGVIALIAGPDVVRFTPSLIIPEQDVKEGLARFARAVA
RICS

Specific function: Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=378, Percent_Identity=34.6560846560847, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI13994255, Length=441, Percent_Identity=28.1179138321995, Blast_Score=178, Evalue=8e-45,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=34.4481605351171, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI37574042, Length=408, Percent_Identity=28.921568627451, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI226442705, Length=408, Percent_Identity=28.6764705882353, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226442709, Length=373, Percent_Identity=29.4906166219839, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI24119277, Length=428, Percent_Identity=25.2336448598131, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI188536080, Length=432, Percent_Identity=23.1481481481481, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI38679950, Length=432, Percent_Identity=23.1481481481481, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI38679946, Length=432, Percent_Identity=23.1481481481481, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1788044, Length=404, Percent_Identity=71.5346534653465, Blast_Score=600, Evalue=1e-173,
Organism=Escherichia coli, GI1789759, Length=397, Percent_Identity=61.9647355163728, Blast_Score=526, Evalue=1e-151,
Organism=Escherichia coli, GI1789016, Length=392, Percent_Identity=34.9489795918367, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI145693181, Length=409, Percent_Identity=34.9633251833741, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1787560, Length=389, Percent_Identity=32.6478149100257, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1786349, Length=308, Percent_Identity=33.4415584415584, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1786991, Length=313, Percent_Identity=32.2683706070287, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=377, Percent_Identity=35.2785145888594, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI32564660, Length=435, Percent_Identity=29.1954022988506, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI25144274, Length=283, Percent_Identity=33.9222614840989, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=426, Percent_Identity=27.6995305164319, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI71981843, Length=162, Percent_Identity=35.1851851851852, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17541228, Length=422, Percent_Identity=24.8815165876777, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=404, Percent_Identity=39.6039603960396, Blast_Score=283, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6323470, Length=401, Percent_Identity=32.4189526184539, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324386, Length=302, Percent_Identity=30.794701986755, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6321456, Length=379, Percent_Identity=26.3852242744063, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=34.9206349206349, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI28574759, Length=429, Percent_Identity=30.3030303030303, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI161085790, Length=428, Percent_Identity=30.1401869158879, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21356575, Length=423, Percent_Identity=27.4231678486998, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281366494, Length=299, Percent_Identity=26.7558528428094, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24667139, Length=299, Percent_Identity=26.7558528428094, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24667143, Length=299, Percent_Identity=26.7558528428094, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.81 [H]

Molecular weight: Translated: 43133; Mature: 43133

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQPIAVTRQSFDDWMVPVYAPADFILVRGEGSQVWDQQGKSYIDFAGGIAVNALGHAHP
CCCCHHHHHHCCCCCCEEEECCCCEEEEECCCCHHHHHCCCEEEEECCCEEECCCCCHHH
VVTAALVEQAGKLWHLGNGYTNEPVLRLAKQLIDATFADKVFFCNSGAEANEAALKLARK
HHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHH
RALDQGNSSKNQIVAFNNAFHGRTLFTVSAGGQPKYSKDFAPLPGGITHTPFNDLAAAAE
HHHCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
VINDHTCAVIVEPIQGEGGVLPADPAFLQGLRELCDRHDAVLIFDEVQTGMGRTGELYAY
HHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEEE
TQYGVVPDVLTTAKALGCGFPIGAMLTTDELAKTLGVGTHGTTYGGNPLATAVAGAVFSI
EECCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
INTPEVLDGVKQRHQWFLDGLNKINQQYPIFSEIRGGGLLIGCQLTQDYAGKAKQITQLA
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECHHHCCHHHHHHHHC
NEEGVIALIAGPDVVRFTPSLIIPEQDVKEGLARFARAVARICS
CCCCEEEEEECCCEEEECCCEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQPIAVTRQSFDDWMVPVYAPADFILVRGEGSQVWDQQGKSYIDFAGGIAVNALGHAHP
CCCCHHHHHHCCCCCCEEEECCCCEEEEECCCCHHHHHCCCEEEEECCCEEECCCCCHHH
VVTAALVEQAGKLWHLGNGYTNEPVLRLAKQLIDATFADKVFFCNSGAEANEAALKLARK
HHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHH
RALDQGNSSKNQIVAFNNAFHGRTLFTVSAGGQPKYSKDFAPLPGGITHTPFNDLAAAAE
HHHCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
VINDHTCAVIVEPIQGEGGVLPADPAFLQGLRELCDRHDAVLIFDEVQTGMGRTGELYAY
HHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEEE
TQYGVVPDVLTTAKALGCGFPIGAMLTTDELAKTLGVGTHGTTYGGNPLATAVAGAVFSI
EECCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
INTPEVLDGVKQRHQWFLDGLNKINQQYPIFSEIRGGGLLIGCQLTQDYAGKAKQITQLA
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECHHHCCHHHHHHHHC
NEEGVIALIAGPDVVRFTPSLIIPEQDVKEGLARFARAVARICS
CCCCEEEEEECCCEEEECCCEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA