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The map label for this gene is 157371063

Identifier: 157371063

GI number: 157371063

Start: 3104179

End: 3105177

Strand: Reverse

Name: 157371063

Synonym: Spro_2823

Alternate gene names: NA

Gene position: 3105177-3104179 (Counterclockwise)

Preceding gene: 157371065

Following gene: 157371062

Centisome position: 56.99

GC content: 56.36

Gene sequence:

>999_bases
TTGAAGATAACCAATCGTTACTATGATGCCGGCAAAACGCACCATACCCCGCAGGGGTTTCGTAACCCGGAGCCTTCGCA
GCGTCGGGATGGGGATTTGAAACGCTGGCAGAACGAGCGTAAACAGCAGGGGTTGCCCAAACCTCCGCAGATGGGCTATC
AGCAGTTTACCCAGCGCTGGTGGCAACGTGCCGACCTTGGCGGCAGCGATAACAGCATTTGGTGGTTGGGGCACGCCTCA
ATGCTGCTGCGCCTGGATGGCCGATACATCCTGATCGACCCGGTATTGTCTGAACGTGCATCGCCGCTGAGTTTCTATGG
CCCAAAGCGCAAAACACCGCCGCCGTTGACGGTGCAACAGTTGCCGGCAGTGGACGTGGTTTTAATCTCCCACAATCACT
ATGACCATCTCGATCGGCGCACCGTGCGGCAGTTGGCACGGCGTTTTCCGCACGCGACCTTTATTGTGCCCTTGGGGCTG
AAAAACTGGTTCCGACGTTACCGGCTGCAACGGGTAGAAGAGCTGGACTGGTGGGATAGCCTGCAGTTGGGCGATTTGAC
TTTCTATTGCACGCCGGCGCGTCACTGGAGCATGCGTACCCTGTGGGACCGCAATCGCTCTCTCTGGTGCGGTTGGGTGA
TTCATCATCCGGCGCTGCGTTTCTATTTTTCCGGAGACAGCGGTTATTCGGATCGCCTGGCAGATATTGGCACCCGTTTA
GGGCCGTTTGACGTGGCGGCATTACCGATTGGCGCCTACGCACCACGTTGGTTCATGCAGGAACAACATATGGATCCGCA
GCAGTCGGTGACGCTGTATCAACAATTAAATGCGCCGCGGGTCATTCCGATCCATTGGGGCGTTTTTGAGTTGGCCGATG
AGTCGTTGGATGAACCGCCGCAGCAATTAAATCTGGCTCTGAGTGCGGCGGGAATAGAGCAGCACCAGTTTCGGCCCATC
AAAATTGGCGAGCGCATTGCGCTTGATGCTAACTCTTAA

Upstream 100 bases:

>100_bases
TCACTCAAGGTGAGCACGGTTCACAAAGCACGCCGATCGAGTATCTTGTTATGTTATTCACCTGCCCGTGTTGGGTGTCC
GCAGTGGTCGGGAGAGCAAT

Downstream 100 bases:

>100_bases
GCGTTATTCCTGGTCCTGTGTGGCGGGGGCTGTTGTCGTCACCGTCTGCAGGCCAGTCCCAATGCGGGTTGTAGCCATTC
GGTGGTGCAGGGCCTGGCTT

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKITNRYYDAGKTHHTPQGFRNPEPSQRRDGDLKRWQNERKQQGLPKPPQMGYQQFTQRWWQRADLGGSDNSIWWLGHAS
MLLRLDGRYILIDPVLSERASPLSFYGPKRKTPPPLTVQQLPAVDVVLISHNHYDHLDRRTVRQLARRFPHATFIVPLGL
KNWFRRYRLQRVEELDWWDSLQLGDLTFYCTPARHWSMRTLWDRNRSLWCGWVIHHPALRFYFSGDSGYSDRLADIGTRL
GPFDVAALPIGAYAPRWFMQEQHMDPQQSVTLYQQLNAPRVIPIHWGVFELADESLDEPPQQLNLALSAAGIEQHQFRPI
KIGERIALDANS

Sequences:

>Translated_332_residues
MKITNRYYDAGKTHHTPQGFRNPEPSQRRDGDLKRWQNERKQQGLPKPPQMGYQQFTQRWWQRADLGGSDNSIWWLGHAS
MLLRLDGRYILIDPVLSERASPLSFYGPKRKTPPPLTVQQLPAVDVVLISHNHYDHLDRRTVRQLARRFPHATFIVPLGL
KNWFRRYRLQRVEELDWWDSLQLGDLTFYCTPARHWSMRTLWDRNRSLWCGWVIHHPALRFYFSGDSGYSDRLADIGTRL
GPFDVAALPIGAYAPRWFMQEQHMDPQQSVTLYQQLNAPRVIPIHWGVFELADESLDEPPQQLNLALSAAGIEQHQFRPI
KIGERIALDANS
>Mature_332_residues
MKITNRYYDAGKTHHTPQGFRNPEPSQRRDGDLKRWQNERKQQGLPKPPQMGYQQFTQRWWQRADLGGSDNSIWWLGHAS
MLLRLDGRYILIDPVLSERASPLSFYGPKRKTPPPLTVQQLPAVDVVLISHNHYDHLDRRTVRQLARRFPHATFIVPLGL
KNWFRRYRLQRVEELDWWDSLQLGDLTFYCTPARHWSMRTLWDRNRSLWCGWVIHHPALRFYFSGDSGYSDRLADIGTRL
GPFDVAALPIGAYAPRWFMQEQHMDPQQSVTLYQQLNAPRVIPIHWGVFELADESLDEPPQQLNLALSAAGIEQHQFRPI
KIGERIALDANS

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=263, Percent_Identity=44.8669201520913, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI170932481, Length=263, Percent_Identity=44.8669201520913, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17543102, Length=268, Percent_Identity=40.2985074626866, Blast_Score=216, Evalue=9e-57,
Organism=Caenorhabditis elegans, GI17543100, Length=262, Percent_Identity=40.4580152671756, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI25148824, Length=268, Percent_Identity=40.2985074626866, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17543104, Length=262, Percent_Identity=40.0763358778626, Blast_Score=207, Evalue=6e-54,
Organism=Saccharomyces cerevisiae, GI6325154, Length=262, Percent_Identity=33.587786259542, Blast_Score=152, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38879; Mature: 38879

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITNRYYDAGKTHHTPQGFRNPEPSQRRDGDLKRWQNERKQQGLPKPPQMGYQQFTQRW
CCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
WQRADLGGSDNSIWWLGHASMLLRLDGRYILIDPVLSERASPLSFYGPKRKTPPPLTVQQ
HHHHCCCCCCCCEEEEECCEEEEEECCCEEEECCHHHCCCCCCCCCCCCCCCCCCCCHHH
LPAVDVVLISHNHYDHLDRRTVRQLARRFPHATFIVPLGLKNWFRRYRLQRVEELDWWDS
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
LQLGDLTFYCTPARHWSMRTLWDRNRSLWCGWVIHHPALRFYFSGDSGYSDRLADIGTRL
CEECCEEEEECCCCCCCHHHHHHCCCCEEEEEEEECCEEEEEECCCCCCHHHHHHHHCCC
GPFDVAALPIGAYAPRWFMQEQHMDPQQSVTLYQQLNAPRVIPIHWGVFELADESLDEPP
CCCCEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCH
QQLNLALSAAGIEQHQFRPIKIGERIALDANS
HHHEEEHEECCCHHHCCCCEECCCEEEEECCC
>Mature Secondary Structure
MKITNRYYDAGKTHHTPQGFRNPEPSQRRDGDLKRWQNERKQQGLPKPPQMGYQQFTQRW
CCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
WQRADLGGSDNSIWWLGHASMLLRLDGRYILIDPVLSERASPLSFYGPKRKTPPPLTVQQ
HHHHCCCCCCCCEEEEECCEEEEEECCCEEEECCHHHCCCCCCCCCCCCCCCCCCCCHHH
LPAVDVVLISHNHYDHLDRRTVRQLARRFPHATFIVPLGLKNWFRRYRLQRVEELDWWDS
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
LQLGDLTFYCTPARHWSMRTLWDRNRSLWCGWVIHHPALRFYFSGDSGYSDRLADIGTRL
CEECCEEEEECCCCCCCHHHHHHCCCCEEEEEEEECCEEEEEECCCCCCHHHHHHHHCCC
GPFDVAALPIGAYAPRWFMQEQHMDPQQSVTLYQQLNAPRVIPIHWGVFELADESLDEPP
CCCCEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCH
QQLNLALSAAGIEQHQFRPIKIGERIALDANS
HHHEEEHEECCCHHHCCCCEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]