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The map label for this gene is argS

Identifier: 157371031

GI number: 157371031

Start: 3070077

End: 3071807

Strand: Direct

Name: argS

Synonym: Spro_2791

Alternate gene names: 157371031

Gene position: 3070077-3071807 (Clockwise)

Preceding gene: 157371029

Following gene: 157371036

Centisome position: 56.34

GC content: 56.04

Gene sequence:

>1731_bases
GTGAATATTCAGGTTCTTCTTTCAGATAAAGTCAGCCAGGCGCTGATTGCCGCAGGCGCGCCAGCCGATTGCGAAGCGCA
GGTCCGTCAATCAGCAAAAGCACAGTTCGGTGATTATCAGGCCAATGGCGTGATGTCCGTCGCCAAAAAACTCGGCATGC
CGCCGCGCCAGTTAGCGGAAAAAGTGGTGCAACTGCTTGACCTCGGCGACGTCGCCAGCAAAGTGGAAATCGCCGGCCCC
GGCTTTATCAATATTTTCCTGAACAGCCAATGGGTTGCCCAGCAAGCCGATCGCGTGCTGAGTGCGCCAAAACTCGATAT
TGCACCAGTCAAGCAACAGACCATCGTTATTGACTACTCTGCCCCCAACGTGGCGAAAGAAATGCACGTCGGCCACCTGC
GCTCCACCATTATCGGTGACGCCGCCGCACGTACCCAGGAGTTCCTGGGCCACAAGGTGATCCGCGCTAACCACGTTGGC
GACTGGGGCACCCAGTTCGGCATGTTAATCGCCTATCTGGAAAAAATGCAGAACGAGAACGCCAGCGATATGGGTCTGTC
CGACCTGGAACAGTTCTACCGCGAAGCGAAGAAACACTATGACGAAGACGCCGATTTTGCCGAGCGCGCTCGCGCCTATG
TGGTGAAGTTGCAAGGCGGCGACCAGTACTGTCTGAAGATGTGGCGCAAGCTGGTCGACATTACCATGGCACAAAACCAG
CTGACCTATAACCGTCTGAACGTCACCCTGACCGAAGACGACGTGATGGGTGAAAGCCTGTACAACGCGATGCTGCCGGG
GATTGTTGCCGATCTCAAGGCCAAGGGTCTGGCGGTGGAAAGCGAAGGCGCCACCGTGGTATTCCTCGATGAATACAAGA
ATAAAGACGGCGAGCCGATGGGCGTCATCATCCAGAAAAAGGATGGCGGCTACCTGTACACCACTACCGATATTGCCTGT
GCCAAATACCGTTATGAAACGCTGGGCGCCGATCGTGTGCTGTATTACATCGACTCGCGTCAGCACCAGCACCTGATGCA
GGCCTGGACCATAGTGCGTAAAGCCGGCTATATCCCGGACTCGCTGTCGCTGGAACACCACATGTTCGGCATGATGTTGG
GTAAAGACGGCAAGCCGTTCAAAACCCGCTCAGGCGGCACGGTGAAACTGTCCGATCTGCTGGATGAAGCGGTGGACCGC
GCCGGCAAACTGATCGCCGAGAAAAACCCGGATATGCCGGCAGAAGAAATGCAAAGCCTGGCCAATGCCGTTGGCATCGG
TGCGGTGAAATACGCCGACCTGTCAAAAAGCCGGACTACCGATTACATCTTCGACTGGGATAACATGCTGGCGTTTGAAG
GCAATACCGCACCTTATATGCAGTATGCCTATACCCGCGTTGCCTCGGTGTTCAAACGCGCCGGTGTCGATGAAAGCAAC
CTGACCCTGCCACTGGTGATGACCGAAGAGCGTGAAATCACGCTGGCAACCCGTCTGCTGCAGTTTGAAGAGGTGATCAC
CACCGTAGCGCGCGAAGGCACCCCACACGTGATGTGTAGCTACCTGTATGACCTCGCGGGCCTGTTCTCCGGCTTCTACG
AGCACTGCCAGATCCTCAATGCGGACAGCGAAGAAGCGCGTCAGAGCCGCCTGAAACTGTCACTGTTGACCGCCAAAACG
TTGAAGGTCGGTCTGGACACGCTGGGCATCGAAACCGTCGAACGTATGTAA

Upstream 100 bases:

>100_bases
TTTGTGGTGGGCCGCCGTGTTGACGCGCAGCCAAAAAAACCACCTTTGAATCCCGCAGGGGCATGGCATACGGCCCCTCG
TTCGTCATTAAGGTAACCCG

Downstream 100 bases:

>100_bases
CCTCTCGGGGTTGAATACGAAAAAGGGTCGCCACGGCGACCCTTTTTTATGCTTTGGCAACGGCAATATCCGTTTATGCC
ACCCGGCGTGCAAAGTCGCG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MNIQVLLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMSVAKKLGMPPRQLAEKVVQLLDLGDVASKVEIAGP
GFINIFLNSQWVAQQADRVLSAPKLDIAPVKQQTIVIDYSAPNVAKEMHVGHLRSTIIGDAAARTQEFLGHKVIRANHVG
DWGTQFGMLIAYLEKMQNENASDMGLSDLEQFYREAKKHYDEDADFAERARAYVVKLQGGDQYCLKMWRKLVDITMAQNQ
LTYNRLNVTLTEDDVMGESLYNAMLPGIVADLKAKGLAVESEGATVVFLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLGADRVLYYIDSRQHQHLMQAWTIVRKAGYIPDSLSLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVDR
AGKLIAEKNPDMPAEEMQSLANAVGIGAVKYADLSKSRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASVFKRAGVDESN
LTLPLVMTEEREITLATRLLQFEEVITTVAREGTPHVMCSYLYDLAGLFSGFYEHCQILNADSEEARQSRLKLSLLTAKT
LKVGLDTLGIETVERM

Sequences:

>Translated_576_residues
MNIQVLLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMSVAKKLGMPPRQLAEKVVQLLDLGDVASKVEIAGP
GFINIFLNSQWVAQQADRVLSAPKLDIAPVKQQTIVIDYSAPNVAKEMHVGHLRSTIIGDAAARTQEFLGHKVIRANHVG
DWGTQFGMLIAYLEKMQNENASDMGLSDLEQFYREAKKHYDEDADFAERARAYVVKLQGGDQYCLKMWRKLVDITMAQNQ
LTYNRLNVTLTEDDVMGESLYNAMLPGIVADLKAKGLAVESEGATVVFLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLGADRVLYYIDSRQHQHLMQAWTIVRKAGYIPDSLSLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVDR
AGKLIAEKNPDMPAEEMQSLANAVGIGAVKYADLSKSRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASVFKRAGVDESN
LTLPLVMTEEREITLATRLLQFEEVITTVAREGTPHVMCSYLYDLAGLFSGFYEHCQILNADSEEARQSRLKLSLLTAKT
LKVGLDTLGIETVERM
>Mature_576_residues
MNIQVLLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMSVAKKLGMPPRQLAEKVVQLLDLGDVASKVEIAGP
GFINIFLNSQWVAQQADRVLSAPKLDIAPVKQQTIVIDYSAPNVAKEMHVGHLRSTIIGDAAARTQEFLGHKVIRANHVG
DWGTQFGMLIAYLEKMQNENASDMGLSDLEQFYREAKKHYDEDADFAERARAYVVKLQGGDQYCLKMWRKLVDITMAQNQ
LTYNRLNVTLTEDDVMGESLYNAMLPGIVADLKAKGLAVESEGATVVFLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLGADRVLYYIDSRQHQHLMQAWTIVRKAGYIPDSLSLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVDR
AGKLIAEKNPDMPAEEMQSLANAVGIGAVKYADLSKSRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASVFKRAGVDESN
LTLPLVMTEEREITLATRLLQFEEVITTVAREGTPHVMCSYLYDLAGLFSGFYEHCQILNADSEEARQSRLKLSLLTAKT
LKVGLDTLGIETVERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=568, Percent_Identity=37.8521126760563, Blast_Score=383, Evalue=1e-106,
Organism=Homo sapiens, GI197100773, Length=473, Percent_Identity=31.9238900634249, Blast_Score=220, Evalue=3e-57,
Organism=Escherichia coli, GI1788184, Length=577, Percent_Identity=80.4159445407279, Blast_Score=981, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=570, Percent_Identity=38.4210526315789, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71985068, Length=530, Percent_Identity=39.2452830188679, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17532153, Length=381, Percent_Identity=28.8713910761155, Blast_Score=154, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320548, Length=543, Percent_Identity=33.7016574585635, Blast_Score=260, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6321883, Length=535, Percent_Identity=28.411214953271, Blast_Score=210, Evalue=6e-55,
Organism=Drosophila melanogaster, GI18859963, Length=567, Percent_Identity=36.68430335097, Blast_Score=386, Evalue=1e-107,
Organism=Drosophila melanogaster, GI28571570, Length=487, Percent_Identity=30.1848049281314, Blast_Score=181, Evalue=9e-46,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_SERP5 (A8GFK2)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001479020.1
- ProteinModelPortal:   A8GFK2
- SMR:   A8GFK2
- STRING:   A8GFK2
- GeneID:   5607383
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2791
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- ProtClustDB:   PRK01611
- BioCyc:   SPRO399741:SPRO_2791-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63990; Mature: 63990

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQVLLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMSVAKKLGMPPRQLAE
CCEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHH
KVVQLLDLGDVASKVEIAGPGFINIFLNSQWVAQQADRVLSAPKLDIAPVKQQTIVIDYS
HHHHHHHHCCHHCEEEECCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEC
APNVAKEMHVGHLRSTIIGDAAARTQEFLGHKVIRANHVGDWGTQFGMLIAYLEKMQNEN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHCCCC
ASDMGLSDLEQFYREAKKHYDEDADFAERARAYVVKLQGGDQYCLKMWRKLVDITMAQNQ
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
LTYNRLNVTLTEDDVMGESLYNAMLPGIVADLKAKGLAVESEGATVVFLDEYKNKDGEPM
EEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLGADRVLYYIDSRQHQHLMQAWTIVRKAGYIPD
EEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SLSLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVDRAGKLIAEKNPDMPAEEMQSL
CCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ANAVGIGAVKYADLSKSRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASVFKRAGVDESN
HHHHCCCCEEECCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
LTLPLVMTEEREITLATRLLQFEEVITTVAREGTPHVMCSYLYDLAGLFSGFYEHCQILN
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEECC
ADSEEARQSRLKLSLLTAKTLKVGLDTLGIETVERM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC
>Mature Secondary Structure
MNIQVLLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMSVAKKLGMPPRQLAE
CCEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHH
KVVQLLDLGDVASKVEIAGPGFINIFLNSQWVAQQADRVLSAPKLDIAPVKQQTIVIDYS
HHHHHHHHCCHHCEEEECCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEC
APNVAKEMHVGHLRSTIIGDAAARTQEFLGHKVIRANHVGDWGTQFGMLIAYLEKMQNEN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHCCCC
ASDMGLSDLEQFYREAKKHYDEDADFAERARAYVVKLQGGDQYCLKMWRKLVDITMAQNQ
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
LTYNRLNVTLTEDDVMGESLYNAMLPGIVADLKAKGLAVESEGATVVFLDEYKNKDGEPM
EEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLGADRVLYYIDSRQHQHLMQAWTIVRKAGYIPD
EEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SLSLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVDRAGKLIAEKNPDMPAEEMQSL
CCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ANAVGIGAVKYADLSKSRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASVFKRAGVDESN
HHHHCCCCEEECCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
LTLPLVMTEEREITLATRLLQFEEVITTVAREGTPHVMCSYLYDLAGLFSGFYEHCQILN
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEECC
ADSEEARQSRLKLSLLTAKTLKVGLDTLGIETVERM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA