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The map label for this gene is ruvB

Identifier: 157371016

GI number: 157371016

Start: 3056765

End: 3057769

Strand: Reverse

Name: ruvB

Synonym: Spro_2776

Alternate gene names: 157371016

Gene position: 3057769-3056765 (Counterclockwise)

Preceding gene: 157371017

Following gene: 157371013

Centisome position: 56.12

GC content: 57.81

Gene sequence:

>1005_bases
ATGATTGAAGCCGATCGCCTGATTTCTGCCGAACCGATCAATGAAGAAGAAATTCTTGATCGCGCCATCCGGCCGAAGCT
GCTGACGGAGTACGTCGGTCAGCCACATGTCCGCGAGCAGATGGAAATCTTTATTCAGGCGGCCAAGCAGCGTGGCGACG
CGCTGGACCACCTGCTGATTTTCGGTCCGCCGGGGCTGGGTAAAACCACGCTGGCCAACATCGTTGCCAATGAAATGGGC
GTTAACCTGCGTACCACTTCCGGGCCGGTATTGGAGAAGGCGGGCGATCTGGCGGCGATGCTGACCAACCTCGAGCCACA
CGACGTGCTGTTCATCGATGAAATCCACCGCCTCTCTCCGGTAGTAGAAGAAGTGCTGTACCCGGCGATGGAAGATTACC
AACTGGATATCATGATCGGCGAAGGCCCGGCCGCTCGCTCGATCAAACTCGATTTGCCGCCGTTCACGCTGGTGGGCGCA
ACCACCCGTGCCGGTTCACTGACGTCGCCATTGCGTGACCGCTTCGGTATTGTGCAGCGCCTGGAGTTTTATCAGGTCGC
CGATTTGCAACATATCGTTTCACGCAGCGCTAATTGCCTGGGGTTGGATCTGTCGGAAGAGGGCGCCCATCAGGTAGCTC
GTCGTGCGCGCGGCACACCGCGTATTGCCAACCGTTTACTGCGCCGGGTGCGTGACTTTGCCGAAGTTCGCGCCAATGGC
GTCATCAATGGCGAAGTGGCGATGCAGGCGCTGGATATGTTGAACGTCGACGCCGAAGGTTTTGACTATATGGACCGCAA
GCTGTTGCTGGCGATTATCGACAAGTTCACCGGCGGGCCAGTGGGCCTGGATAACCTGGCGGCGGCGATTGGTGAGGAGC
GAGAAACTATCGAAGACGTTATCGAACCCTTCCTGATCCAGCAGGGTTTTATCCAGCGCACACCGCGTGGGCGCATGGCG
ACCAATCATGCCTATAAGCACTTTGGCATGGTGCGCGAAGAGTAA

Upstream 100 bases:

>100_bases
GCCGTATGGTCAGCAAAATCGCCAAGCCTGGCGCCGATTGCGAAACCCTGATCCGCGACGCGTTGCGCGCCGCGCTGTAA
GCGCCGATAAGGGATAGAGA

Downstream 100 bases:

>100_bases
GAGAACTCTGTGCATTAAAAAAGGGCCGCAATTGATTCAATTGCGGCCCTTTTGACATCGGTAGCTGCCGGGGGTCAGGC
TTGCTGCTTCTTGGACAAGC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MIEADRLISAEPINEEEILDRAIRPKLLTEYVGQPHVREQMEIFIQAAKQRGDALDHLLIFGPPGLGKTTLANIVANEMG
VNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGA
TTRAGSLTSPLRDRFGIVQRLEFYQVADLQHIVSRSANCLGLDLSEEGAHQVARRARGTPRIANRLLRRVRDFAEVRANG
VINGEVAMQALDMLNVDAEGFDYMDRKLLLAIIDKFTGGPVGLDNLAAAIGEERETIEDVIEPFLIQQGFIQRTPRGRMA
TNHAYKHFGMVREE

Sequences:

>Translated_334_residues
MIEADRLISAEPINEEEILDRAIRPKLLTEYVGQPHVREQMEIFIQAAKQRGDALDHLLIFGPPGLGKTTLANIVANEMG
VNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGA
TTRAGSLTSPLRDRFGIVQRLEFYQVADLQHIVSRSANCLGLDLSEEGAHQVARRARGTPRIANRLLRRVRDFAEVRANG
VINGEVAMQALDMLNVDAEGFDYMDRKLLLAIIDKFTGGPVGLDNLAAAIGEERETIEDVIEPFLIQQGFIQRTPRGRMA
TNHAYKHFGMVREE
>Mature_334_residues
MIEADRLISAEPINEEEILDRAIRPKLLTEYVGQPHVREQMEIFIQAAKQRGDALDHLLIFGPPGLGKTTLANIVANEMG
VNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGA
TTRAGSLTSPLRDRFGIVQRLEFYQVADLQHIVSRSANCLGLDLSEEGAHQVARRARGTPRIANRLLRRVRDFAEVRANG
VINGEVAMQALDMLNVDAEGFDYMDRKLLLAIIDKFTGGPVGLDNLAAAIGEERETIEDVIEPFLIQQGFIQRTPRGRMA
TNHAYKHFGMVREE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=334, Percent_Identity=85.6287425149701, Blast_Score=579, Evalue=1e-167,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_SERP5 (A8GFI7)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001479005.1
- ProteinModelPortal:   A8GFI7
- SMR:   A8GFI7
- STRING:   A8GFI7
- GeneID:   5605548
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2776
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   SPRO399741:SPRO_2776-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37092; Mature: 37092

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEADRLISAEPINEEEILDRAIRPKLLTEYVGQPHVREQMEIFIQAAKQRGDALDHLLI
CCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCEEEE
FGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHH
VVEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGSLTSPLRDRFGIVQR
HHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHH
LEFYQVADLQHIVSRSANCLGLDLSEEGAHQVARRARGTPRIANRLLRRVRDFAEVRANG
HHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
VINGEVAMQALDMLNVDAEGFDYMDRKLLLAIIDKFTGGPVGLDNLAAAIGEERETIEDV
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHH
IEPFLIQQGFIQRTPRGRMATNHAYKHFGMVREE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIEADRLISAEPINEEEILDRAIRPKLLTEYVGQPHVREQMEIFIQAAKQRGDALDHLLI
CCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCEEEE
FGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHH
VVEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGSLTSPLRDRFGIVQR
HHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHH
LEFYQVADLQHIVSRSANCLGLDLSEEGAHQVARRARGTPRIANRLLRRVRDFAEVRANG
HHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
VINGEVAMQALDMLNVDAEGFDYMDRKLLLAIIDKFTGGPVGLDNLAAAIGEERETIEDV
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHH
IEPFLIQQGFIQRTPRGRMATNHAYKHFGMVREE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA