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The map label for this gene is ruvA

Identifier: 157371017

GI number: 157371017

Start: 3057790

End: 3058401

Strand: Reverse

Name: ruvA

Synonym: Spro_2777

Alternate gene names: 157371017

Gene position: 3058401-3057790 (Counterclockwise)

Preceding gene: 157371018

Following gene: 157371016

Centisome position: 56.13

GC content: 56.05

Gene sequence:

>612_bases
ATGATAGGTCGTCTCAGAGGATATATTCTGGAAAAGCAGCCGCCGCTGGTGTTACTGGAGGCAAACGGTGTGGGCTATGA
AGTGCATATGCCGATGACCTGCTTTTATGAGCTGCCGGAACTGGGGCAAGAGGCTATCGTGTTTACCCAATTCGTGGTGC
GCGAAGATGCACAGCTGCTGTACGGTTTTAATGATAAGCAAGAGCGTGCGCTGTTCCGCGAGTTGATCAAAGTCAACGGC
GTGGGGCCAAAGCTGGCGCTGGCCATTTTGTCCGGCATGTCCGCGCAACAGTTCGTCAGCGCGGTAGAGCGTGAAGAGAT
CACTTCATTGGTGAAATTGCCGGGCGTAGGCAAGAAAACCGCTGAGCGCCTGGTGGTGGAAATGAAAGACCGCTTCAAAG
GGCTTAATGGCGATCTGTTCAATAACAGCAGTGAAATCACGCTGCCAACCGCAGCGCAAGCCGCCGAGTTGGACGCGGAA
GCCGAGGCAGCATCTGCACTGGTGGCATTAGGCTACAAGCCGCAGGAAGCCAGCCGTATGGTCAGCAAAATCGCCAAGCC
TGGCGCCGATTGCGAAACCCTGATCCGCGACGCGTTGCGCGCCGCGCTGTAA

Upstream 100 bases:

>100_bases
TTAAACTTAGGCTGGATATTCATCCAGCCTTTTTTATGTTATAAGCTTTACCAGCACGGCATGACAGCAGGTCATGCTCA
TGAATTCTGCAGGAGGGTAA

Downstream 100 bases:

>100_bases
GCGCCGATAAGGGATAGAGAATGATTGAAGCCGATCGCCTGATTTCTGCCGAACCGATCAATGAAGAAGAAATTCTTGAT
CGCGCCATCCGGCCGAAGCT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MIGRLRGYILEKQPPLVLLEANGVGYEVHMPMTCFYELPELGQEAIVFTQFVVREDAQLLYGFNDKQERALFRELIKVNG
VGPKLALAILSGMSAQQFVSAVEREEITSLVKLPGVGKKTAERLVVEMKDRFKGLNGDLFNNSSEITLPTAAQAAELDAE
AEAASALVALGYKPQEASRMVSKIAKPGADCETLIRDALRAAL

Sequences:

>Translated_203_residues
MIGRLRGYILEKQPPLVLLEANGVGYEVHMPMTCFYELPELGQEAIVFTQFVVREDAQLLYGFNDKQERALFRELIKVNG
VGPKLALAILSGMSAQQFVSAVEREEITSLVKLPGVGKKTAERLVVEMKDRFKGLNGDLFNNSSEITLPTAAQAAELDAE
AEAASALVALGYKPQEASRMVSKIAKPGADCETLIRDALRAAL
>Mature_203_residues
MIGRLRGYILEKQPPLVLLEANGVGYEVHMPMTCFYELPELGQEAIVFTQFVVREDAQLLYGFNDKQERALFRELIKVNG
VGPKLALAILSGMSAQQFVSAVEREEITSLVKLPGVGKKTAERLVVEMKDRFKGLNGDLFNNSSEITLPTAAQAAELDAE
AEAASALVALGYKPQEASRMVSKIAKPGADCETLIRDALRAAL

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=80.2955665024631, Blast_Score=335, Evalue=1e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_SERP5 (A8GFI8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001479006.1
- ProteinModelPortal:   A8GFI8
- SMR:   A8GFI8
- STRING:   A8GFI8
- GeneID:   5603992
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2777
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LFGFAQK
- ProtClustDB:   PRK00116
- BioCyc:   SPRO399741:SPRO_2777-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22169; Mature: 22169

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLRGYILEKQPPLVLLEANGVGYEVHMPMTCFYELPELGQEAIVFTQFVVREDAQLL
CCCCCCCEEECCCCCEEEEECCCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHCCHHE
YGFNDKQERALFRELIKVNGVGPKLALAILSGMSAQQFVSAVEREEITSLVKLPGVGKKT
ECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLVVEMKDRFKGLNGDLFNNSSEITLPTAAQAAELDAEAEAASALVALGYKPQEASRM
HHHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHCCHHHHHHHHHHHCCCCCHHHHHH
VSKIAKPGADCETLIRDALRAAL
HHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIGRLRGYILEKQPPLVLLEANGVGYEVHMPMTCFYELPELGQEAIVFTQFVVREDAQLL
CCCCCCCEEECCCCCEEEEECCCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHCCHHE
YGFNDKQERALFRELIKVNGVGPKLALAILSGMSAQQFVSAVEREEITSLVKLPGVGKKT
ECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLVVEMKDRFKGLNGDLFNNSSEITLPTAAQAAELDAEAEAASALVALGYKPQEASRM
HHHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHCCHHHHHHHHHHHCCCCCHHHHHH
VSKIAKPGADCETLIRDALRAAL
HHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA