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The map label for this gene is mdtJ

Identifier: 157371006

GI number: 157371006

Start: 3045407

End: 3045775

Strand: Reverse

Name: mdtJ

Synonym: Spro_2766

Alternate gene names: 157371006

Gene position: 3045775-3045407 (Counterclockwise)

Preceding gene: 157371007

Following gene: 157371005

Centisome position: 55.9

GC content: 50.41

Gene sequence:

>369_bases
ATGATTTATTGGATCTTTTTAGGTTTGGCCATAGCGACCGAAATTATCGGTACCCTGTCAATGAAATACGCCAGCATTAG
CGGCGGTATGACCGGCCATATAGTGATGTATGTAATGATCACCGCCTCGTATGTAATGTTGTCGATGGCGGTAAAACGGG
TTGCTCTGGGCGTCGCTTATGCCCTGTGGGAAGGTATCGGTATCCTGTTTATTACCCTGTTTAGCGTGCTGTGGTTTGAC
GAACCGATCTCGGCGTTGAAGGTGCTGGGTCTGGTGACGTTGATTGTCGGCATCATGCTGGTGAAGTCCGGCACCCGCAA
ACCACGAAAACAGGTAACGCCGCGAGGTGACAACCATGCAACAGCTTGA

Upstream 100 bases:

>100_bases
GGGATCTCTGCGTCTTCAGCGCCTGTTTGCGCCTGTCTGACGAGATAAATCGGGATAAATATGCCTTAGCGTGCCTTATT
CGCCGTTTGGGAGAGAAATC

Downstream 100 bases:

>100_bases
GTTGTACCACATTGCTTTTCTGGGATTGGCGATCGTACTGGAGATTATCGCCAACATTTTCCTGAAGATGTCGGACGGTT
TCCGTAAAGTTTGGTTGGGC

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MIYWIFLGLAIATEIIGTLSMKYASISGGMTGHIVMYVMITASYVMLSMAVKRVALGVAYALWEGIGILFITLFSVLWFD
EPISALKVLGLVTLIVGIMLVKSGTRKPRKQVTPRGDNHATA

Sequences:

>Translated_122_residues
MIYWIFLGLAIATEIIGTLSMKYASISGGMTGHIVMYVMITASYVMLSMAVKRVALGVAYALWEGIGILFITLFSVLWFD
EPISALKVLGLVTLIVGIMLVKSGTRKPRKQVTPRGDNHATA
>Mature_122_residues
MIYWIFLGLAIATEIIGTLSMKYASISGGMTGHIVMYVMITASYVMLSMAVKRVALGVAYALWEGIGILFITLFSVLWFD
EPISALKVLGLVTLIVGIMLVKSGTRKPRKQVTPRGDNHATA

Specific function: Catalyzes the excretion of spermidine

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily

Homologues:

Organism=Escherichia coli, GI1787884, Length=119, Percent_Identity=68.9075630252101, Blast_Score=154, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MDTJ_SERP5 (A8GFH7)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478995.1
- STRING:   A8GFH7
- GeneID:   5607364
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2766
- eggNOG:   COG2076
- HOGENOM:   HBG740972
- OMA:   AFWEGLG
- BioCyc:   SPRO399741:SPRO_2766-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01598
- InterPro:   IPR000390

Pfam domain/function: PF00893 Multi_Drug_Res

EC number: NA

Molecular weight: Translated: 13281; Mature: 13281

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2629ac18)-; HASH(0x260b470c)-; HASH(0x25429048)-; HASH(0x25f6691c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYWIFLGLAIATEIIGTLSMKYASISGGMTGHIVMYVMITASYVMLSMAVKRVALGVAY
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALWEGIGILFITLFSVLWFDEPISALKVLGLVTLIVGIMLVKSGTRKPRKQVTPRGDNHA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCC
TA
CH
>Mature Secondary Structure
MIYWIFLGLAIATEIIGTLSMKYASISGGMTGHIVMYVMITASYVMLSMAVKRVALGVAY
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALWEGIGILFITLFSVLWFDEPISALKVLGLVTLIVGIMLVKSGTRKPRKQVTPRGDNHA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCC
TA
CH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA