Click here to switch to the map view.

The map label for this gene is mdtI

Identifier: 157371005

GI number: 157371005

Start: 3045091

End: 3045420

Strand: Reverse

Name: mdtI

Synonym: Spro_2765

Alternate gene names: 157371005

Gene position: 3045420-3045091 (Counterclockwise)

Preceding gene: 157371006

Following gene: 157371003

Centisome position: 55.89

GC content: 53.64

Gene sequence:

>330_bases
ATGCAACAGCTTGAGTTGTACCACATTGCTTTTCTGGGATTGGCGATCGTACTGGAGATTATCGCCAACATTTTCCTGAA
GATGTCGGACGGTTTCCGTAAAGTTTGGTTGGGCCTGCTGTCTCTGCTGTCGGTACTGGGGGCGTTCAGTGCGCTGGCGC
AGGCGGTGAAGGGGATTGATCTTTCGGTTGCCTATGCGCTGTGGGGCGGTTTCGGTATCGCCGCGACAATCGCTGCCGGC
TGGATCCTGTTTGGTCAACGGTTAAATGCCAAGGGCTGGATTGGTCTGGTATTGTTACTGGCGGGGATGGTGATCATCAA
ACTGGCTTAA

Upstream 100 bases:

>100_bases
TTGAAGGTGCTGGGTCTGGTGACGTTGATTGTCGGCATCATGCTGGTGAAGTCCGGCACCCGCAAACCACGAAAACAGGT
AACGCCGCGAGGTGACAACC

Downstream 100 bases:

>100_bases
TCAGCCGCAAACACGACAAAATAAAACCGCAGGCGTTATCGTCTGCGGTTTTTTGCGTTACAGCGCGGCAATGATTTTGA
TTTCAACCTTGTACTTCGGA

Product: multidrug efflux system protein MdtI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 109

Protein sequence:

>109_residues
MQQLELYHIAFLGLAIVLEIIANIFLKMSDGFRKVWLGLLSLLSVLGAFSALAQAVKGIDLSVAYALWGGFGIAATIAAG
WILFGQRLNAKGWIGLVLLLAGMVIIKLA

Sequences:

>Translated_109_residues
MQQLELYHIAFLGLAIVLEIIANIFLKMSDGFRKVWLGLLSLLSVLGAFSALAQAVKGIDLSVAYALWGGFGIAATIAAG
WILFGQRLNAKGWIGLVLLLAGMVIIKLA
>Mature_109_residues
MQQLELYHIAFLGLAIVLEIIANIFLKMSDGFRKVWLGLLSLLSVLGAFSALAQAVKGIDLSVAYALWGGFGIAATIAAG
WILFGQRLNAKGWIGLVLLLAGMVIIKLA

Specific function: Catalyzes the excretion of spermidine

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtI subfamily

Homologues:

Organism=Escherichia coli, GI1787883, Length=109, Percent_Identity=78.8990825688073, Blast_Score=149, Evalue=4e-38,
Organism=Escherichia coli, GI1786755, Length=98, Percent_Identity=37.7551020408163, Blast_Score=69, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MDTI_SERP5 (A8GFH6)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478994.1
- STRING:   A8GFH6
- GeneID:   5607363
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2765
- eggNOG:   COG2076
- HOGENOM:   HBG740972
- OMA:   IAIGVEI
- ProtClustDB:   PRK10650
- BioCyc:   SPRO399741:SPRO_2765-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01597
- InterPro:   IPR000390

Pfam domain/function: PF00893 Multi_Drug_Res

EC number: NA

Molecular weight: Translated: 11642; Mature: 11642

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x252e3f0c)-; HASH(0x25ac8484)-; HASH(0x25ac7f7c)-; HASH(0x2635d1dc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLELYHIAFLGLAIVLEIIANIFLKMSDGFRKVWLGLLSLLSVLGAFSALAQAVKGID
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSVAYALWGGFGIAATIAAGWILFGQRLNAKGWIGLVLLLAGMVIIKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MQQLELYHIAFLGLAIVLEIIANIFLKMSDGFRKVWLGLLSLLSVLGAFSALAQAVKGID
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSVAYALWGGFGIAATIAAGWILFGQRLNAKGWIGLVLLLAGMVIIKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA