Click here to switch to the map view.

The map label for this gene is udg [H]

Identifier: 157370948

GI number: 157370948

Start: 2984341

End: 2985684

Strand: Reverse

Name: udg [H]

Synonym: Spro_2708

Alternate gene names: 157370948

Gene position: 2985684-2984341 (Counterclockwise)

Preceding gene: 157370949

Following gene: 157370947

Centisome position: 54.79

GC content: 51.79

Gene sequence:

>1344_bases
ATGAAAGTAACAGTTTTTGGTATTGGCTATGTTGGCCTGGTGCAGGCTGCGGTGTTGGCTGAAGTCGGCCACGACGTTAT
GTGTATTGATATAGACGAACGTAAAGTCGAAAACCTGAAGAAAGGGAATATCCCTATTTTTGAGCCAGGCCTGACGCCGT
TGGTGCAGCAAAACTATGAAGCAGGTCGCCTGCAGTTCACCACCGATGCTAAAGCCGGCGTTGAACATGGCACCATTCAG
TTCATTGCCGTGGGCACGCCACCGGATGAAGACGGCTCTGCCGACCTGAAGTATGTGACTGCCGTGGCCCGCACCATCGC
GGAACACATGACCGATCATAAAGTGGTGATCGATAAATCTACCGTACCGGTTGGCACCGCAGATAAAGTCCGTCAGGTTA
TGGAAGAAACGCTGCGCAAACGCGGCAGCACGGTTCCGTTCGATGTGGTTTCCAACCCCGAATTCCTGAAGGAAGGCGCG
GCAGTAGCAGACTGCATGCGTCCTGAGCGCATTGTTATCGGTACCGATAACAAAGATGTGATTGAACCTATTCGCGAGCT
GTATGAGCCGTTCAACCGCAATCACGATCGCATGATCATGATGGATATTCGCAGTGCTGAACTGACCAAGTATGCTGCCA
ACTGTATGCTGGCGACCAAAATCAGCTTTATGAATGAAATGTCTAATCTGGCCGAAATGCTGGGTGCAGACATTGAGAAA
GTGCGTCAGGGTATCGGTTCTGATTCCCGTATTGGCTATCACTTTATCTACCCAGGCTGCGGCTATGGTGGCTCCTGTTT
CCCGAAAGACGTTCAGGCCCTGATCCGCACGGCTGAACATATCGGCTATCAGCCAAAACTGTTGCAAGCCGTAGAGCAGG
TTAACTATCAGCAAAAATATAAGCTGACCAAGTTTATCAAGCATCACTTTGGTGAAGATCTGAAAGGCAAAACCTTTGCG
CTTTGGGGGCTGGCATTCAAGCCAAATACCGATGACATGCGTGAGGCTTCCAGCCGGGTGCTGATGGAGCAACTGTGGGA
AGCGGGTGCTACCGTTCAGGCCTACGACCCTGAAGCCATGAACGAAGTTCAGCGCATCTACGGTCAGCGTGACGATCTGA
AACTGGTAGGTACCAAAGAAGCGGCGCTGCAGGGCGCTGACGCGCTGGTTATCTGTACCGAATGGCAGAACTTCCGCGCG
CCGGATTTCGACGCGATCAAAGGCTCGTTAAAGCAGCCGGTGATCTTTGATGGTCGTAACCTGTTTGATCCTGAGCGCCT
GGAAAGCCGTGGCTTTACCTATTATGCGATTGGTCGCGGTGCGTCCATTCAGCCGGTTATATAA

Upstream 100 bases:

>100_bases
CTGGGCCAAGAGTTCACTCAGTGGTTGAAACAGTTACTGGCCGCTGATAAAAAATAATTTATTCATCTTTCGTCTTAATT
TGAAAAACTAGGATTTTCCC

Downstream 100 bases:

>100_bases
GGGGCATATATGAAATTCCTGGTTACTGGCGCTGCAGGTTTTATTGGTTTTCACGTTGCTGAACGTCTGTTGGCCGCAGG
GCATCAGGTTGTCGGTATTG

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKVTVFGIGYVGLVQAAVLAEVGHDVMCIDIDERKVENLKKGNIPIFEPGLTPLVQQNYEAGRLQFTTDAKAGVEHGTIQ
FIAVGTPPDEDGSADLKYVTAVARTIAEHMTDHKVVIDKSTVPVGTADKVRQVMEETLRKRGSTVPFDVVSNPEFLKEGA
AVADCMRPERIVIGTDNKDVIEPIRELYEPFNRNHDRMIMMDIRSAELTKYAANCMLATKISFMNEMSNLAEMLGADIEK
VRQGIGSDSRIGYHFIYPGCGYGGSCFPKDVQALIRTAEHIGYQPKLLQAVEQVNYQQKYKLTKFIKHHFGEDLKGKTFA
LWGLAFKPNTDDMREASSRVLMEQLWEAGATVQAYDPEAMNEVQRIYGQRDDLKLVGTKEAALQGADALVICTEWQNFRA
PDFDAIKGSLKQPVIFDGRNLFDPERLESRGFTYYAIGRGASIQPVI

Sequences:

>Translated_447_residues
MKVTVFGIGYVGLVQAAVLAEVGHDVMCIDIDERKVENLKKGNIPIFEPGLTPLVQQNYEAGRLQFTTDAKAGVEHGTIQ
FIAVGTPPDEDGSADLKYVTAVARTIAEHMTDHKVVIDKSTVPVGTADKVRQVMEETLRKRGSTVPFDVVSNPEFLKEGA
AVADCMRPERIVIGTDNKDVIEPIRELYEPFNRNHDRMIMMDIRSAELTKYAANCMLATKISFMNEMSNLAEMLGADIEK
VRQGIGSDSRIGYHFIYPGCGYGGSCFPKDVQALIRTAEHIGYQPKLLQAVEQVNYQQKYKLTKFIKHHFGEDLKGKTFA
LWGLAFKPNTDDMREASSRVLMEQLWEAGATVQAYDPEAMNEVQRIYGQRDDLKLVGTKEAALQGADALVICTEWQNFRA
PDFDAIKGSLKQPVIFDGRNLFDPERLESRGFTYYAIGRGASIQPVI
>Mature_447_residues
MKVTVFGIGYVGLVQAAVLAEVGHDVMCIDIDERKVENLKKGNIPIFEPGLTPLVQQNYEAGRLQFTTDAKAGVEHGTIQ
FIAVGTPPDEDGSADLKYVTAVARTIAEHMTDHKVVIDKSTVPVGTADKVRQVMEETLRKRGSTVPFDVVSNPEFLKEGA
AVADCMRPERIVIGTDNKDVIEPIRELYEPFNRNHDRMIMMDIRSAELTKYAANCMLATKISFMNEMSNLAEMLGADIEK
VRQGIGSDSRIGYHFIYPGCGYGGSCFPKDVQALIRTAEHIGYQPKLLQAVEQVNYQQKYKLTKFIKHHFGEDLKGKTFA
LWGLAFKPNTDDMREASSRVLMEQLWEAGATVQAYDPEAMNEVQRIYGQRDDLKLVGTKEAALQGADALVICTEWQNFRA
PDFDAIKGSLKQPVIFDGRNLFDPERLESRGFTYYAIGRGASIQPVI

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=474, Percent_Identity=33.7552742616034, Blast_Score=242, Evalue=4e-64,
Organism=Homo sapiens, GI296040438, Length=376, Percent_Identity=35.3723404255319, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI296040443, Length=329, Percent_Identity=35.258358662614, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI1788340, Length=359, Percent_Identity=28.133704735376, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI48994968, Length=435, Percent_Identity=26.2068965517241, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17560350, Length=461, Percent_Identity=34.2733188720174, Blast_Score=248, Evalue=6e-66,
Organism=Drosophila melanogaster, GI17136908, Length=470, Percent_Identity=34.8936170212766, Blast_Score=254, Evalue=7e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49826; Mature: 49826

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTVFGIGYVGLVQAAVLAEVGHDVMCIDIDERKVENLKKGNIPIFEPGLTPLVQQNYE
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCEECCCCCHHHHCCCC
AGRLQFTTDAKAGVEHGTIQFIAVGTPPDEDGSADLKYVTAVARTIAEHMTDHKVVIDKS
CCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECC
TVPVGTADKVRQVMEETLRKRGSTVPFDVVSNPEFLKEGAAVADCMRPERIVIGTDNKDV
CCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCHHHHHCCCCEEEEECCCHHH
IEPIRELYEPFNRNHDRMIMMDIRSAELTKYAANCMLATKISFMNEMSNLAEMLGADIEK
HHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRQGIGSDSRIGYHFIYPGCGYGGSCFPKDVQALIRTAEHIGYQPKLLQAVEQVNYQQKY
HHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHH
KLTKFIKHHFGEDLKGKTFALWGLAFKPNTDDMREASSRVLMEQLWEAGATVQAYDPEAM
HHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHH
NEVQRIYGQRDDLKLVGTKEAALQGADALVICTEWQNFRAPDFDAIKGSLKQPVIFDGRN
HHHHHHHCCCCCEEEEECHHHHHCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEECCCC
LFDPERLESRGFTYYAIGRGASIQPVI
CCCHHHHHHCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MKVTVFGIGYVGLVQAAVLAEVGHDVMCIDIDERKVENLKKGNIPIFEPGLTPLVQQNYE
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCEECCCCCHHHHCCCC
AGRLQFTTDAKAGVEHGTIQFIAVGTPPDEDGSADLKYVTAVARTIAEHMTDHKVVIDKS
CCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECC
TVPVGTADKVRQVMEETLRKRGSTVPFDVVSNPEFLKEGAAVADCMRPERIVIGTDNKDV
CCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCHHHHHCCCCEEEEECCCHHH
IEPIRELYEPFNRNHDRMIMMDIRSAELTKYAANCMLATKISFMNEMSNLAEMLGADIEK
HHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRQGIGSDSRIGYHFIYPGCGYGGSCFPKDVQALIRTAEHIGYQPKLLQAVEQVNYQQKY
HHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHH
KLTKFIKHHFGEDLKGKTFALWGLAFKPNTDDMREASSRVLMEQLWEAGATVQAYDPEAM
HHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHH
NEVQRIYGQRDDLKLVGTKEAALQGADALVICTEWQNFRAPDFDAIKGSLKQPVIFDGRN
HHHHHHHCCCCCEEEEECHHHHHCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEECCCC
LFDPERLESRGFTYYAIGRGASIQPVI
CCCHHHHHHCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]