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The map label for this gene is sohB [H]

Identifier: 157370899

GI number: 157370899

Start: 2929525

End: 2930571

Strand: Reverse

Name: sohB [H]

Synonym: Spro_2659

Alternate gene names: 157370899

Gene position: 2930571-2929525 (Counterclockwise)

Preceding gene: 157370902

Following gene: 157370897

Centisome position: 53.78

GC content: 55.87

Gene sequence:

>1047_bases
GTGGAGTTTATATCTGTTTACGGCCTGTTTTTGGCCAAAGTCGCGACGGTAGTGATTGCCATCGCCGCGCTGGCGTTGCT
GGCGGTCAGCCTGGGGCAACGCAAGAACCGCCAGAAAGGGGAACTGCAGCTGACTGACCTCGGTGAACAATATCGCGACA
TGCAGCGTGATATGCGCCTGGCGCGCATGGGTGATGCGGAACAAAAGGCCTGGAACAAGCAGTTTAAAAAACAGACCAAG
GCCGATGACAAACTGAAGAAACAACGCGCTAAAGCCGGTGCGGTTGAAGCCACCAAGCCTTGCCTGTACGTGCTGGATTT
CAAAGGCAGCATGGATGCCCATGAGGTGACCTCACTGCGTGAAGAAATCTCGGCGGTGCTGGCGGTGGCGACGCCGCAAG
ACGAAGTGTTGCTGCGGTTGGAAAGCCCGGGTGGGGTGGTACACGGTTACGGCCTGGCGTCATCGCAACTGGCACGTTTG
CGCACCGGCGGTATTCGCCTGACGGTAGCGGTAGACAAGGTGGCGGCCAGTGGGGGCTATATGATGGCCTGCGTGGCGGA
TCGCATTGTTGCGGCTCCCTTTGCCATCATCGGTTCAATTGGTGTTGTGGCGCAAATCCCCAACTTCCACCGCCTGCTGA
AAAAGAATGATATTGATGTAGAGCTGCACACCGCCGGCGAGTTCAAACGCACGCTGACGCTGTTTGGTGAAAATACCGAG
CAGGGGCGTGAGAAATTCCGTGAAGATCTGAACGACACCCATGAGCTGTTTAAACAGTTTGTGCATCAGCAACGTCCATC
GCTGGATATCGACAGCGTGGCGACCGGTGAACATTGGTTCGGCACTCAGGCGAAAGAGAAAGGGCTGATTGACGCTATTG
GCACCAGTGACGATTTACTGATCGCTGAAATGGAGAATCACGAGGTGGTCGGGGTGCGCTATGCACGTCGCAAACGCATG
ATGGACCGTTTTACCGGCAGTGCGGCAGAAAGTGTCGATCGTCTGCTGTTACGCTGGTGGCAGCGTGGTGAAAAGCCACT
GCTTTAA

Upstream 100 bases:

>100_bases
AGGTAGCACAAGGAATTTTTATTTAGCCGCGACAGCCACTGCGTCGGTTGGCTAGAATGAATGAGATAGTACTAACAACC
TGTTAATAAAGGCGGAATCT

Downstream 100 bases:

>100_bases
ACCGCAGAATTAAACATCAAAGGGGCCAAGGCCCCTTTTTAATGCTTAGTCGACTAAATGATATTTATCAGAAAACACGT
GGGCCAAGTGTTTAAACATA

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MEFISVYGLFLAKVATVVIAIAALALLAVSLGQRKNRQKGELQLTDLGEQYRDMQRDMRLARMGDAEQKAWNKQFKKQTK
ADDKLKKQRAKAGAVEATKPCLYVLDFKGSMDAHEVTSLREEISAVLAVATPQDEVLLRLESPGGVVHGYGLASSQLARL
RTGGIRLTVAVDKVAASGGYMMACVADRIVAAPFAIIGSIGVVAQIPNFHRLLKKNDIDVELHTAGEFKRTLTLFGENTE
QGREKFREDLNDTHELFKQFVHQQRPSLDIDSVATGEHWFGTQAKEKGLIDAIGTSDDLLIAEMENHEVVGVRYARRKRM
MDRFTGSAAESVDRLLLRWWQRGEKPLL

Sequences:

>Translated_348_residues
MEFISVYGLFLAKVATVVIAIAALALLAVSLGQRKNRQKGELQLTDLGEQYRDMQRDMRLARMGDAEQKAWNKQFKKQTK
ADDKLKKQRAKAGAVEATKPCLYVLDFKGSMDAHEVTSLREEISAVLAVATPQDEVLLRLESPGGVVHGYGLASSQLARL
RTGGIRLTVAVDKVAASGGYMMACVADRIVAAPFAIIGSIGVVAQIPNFHRLLKKNDIDVELHTAGEFKRTLTLFGENTE
QGREKFREDLNDTHELFKQFVHQQRPSLDIDSVATGEHWFGTQAKEKGLIDAIGTSDDLLIAEMENHEVVGVRYARRKRM
MDRFTGSAAESVDRLLLRWWQRGEKPLL
>Mature_348_residues
MEFISVYGLFLAKVATVVIAIAALALLAVSLGQRKNRQKGELQLTDLGEQYRDMQRDMRLARMGDAEQKAWNKQFKKQTK
ADDKLKKQRAKAGAVEATKPCLYVLDFKGSMDAHEVTSLREEISAVLAVATPQDEVLLRLESPGGVVHGYGLASSQLARL
RTGGIRLTVAVDKVAASGGYMMACVADRIVAAPFAIIGSIGVVAQIPNFHRLLKKNDIDVELHTAGEFKRTLTLFGENTE
QGREKFREDLNDTHELFKQFVHQQRPSLDIDSVATGEHWFGTQAKEKGLIDAIGTSDDLLIAEMENHEVVGVRYARRKRM
MDRFTGSAAESVDRLLLRWWQRGEKPLL

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=349, Percent_Identity=67.0487106017192, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1788064, Length=168, Percent_Identity=30.3571428571429, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 38764; Mature: 38764

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFISVYGLFLAKVATVVIAIAALALLAVSLGQRKNRQKGELQLTDLGEQYRDMQRDMRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHH
ARMGDAEQKAWNKQFKKQTKADDKLKKQRAKAGAVEATKPCLYVLDFKGSMDAHEVTSLR
HHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHH
EEISAVLAVATPQDEVLLRLESPGGVVHGYGLASSQLARLRTGGIRLTVAVDKVAASGGY
HHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCHHHHHHHHCCCEEEEEEEEHHHCCCCE
MMACVADRIVAAPFAIIGSIGVVAQIPNFHRLLKKNDIDVELHTAGEFKRTLTLFGENTE
EHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEECCCCHHHHHEEECCCHH
QGREKFREDLNDTHELFKQFVHQQRPSLDIDSVATGEHWFGTQAKEKGLIDAIGTSDDLL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCEEECCCCCCEE
IAEMENHEVVGVRYARRKRMMDRFTGSAAESVDRLLLRWWQRGEKPLL
EEECCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEFISVYGLFLAKVATVVIAIAALALLAVSLGQRKNRQKGELQLTDLGEQYRDMQRDMRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHH
ARMGDAEQKAWNKQFKKQTKADDKLKKQRAKAGAVEATKPCLYVLDFKGSMDAHEVTSLR
HHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHH
EEISAVLAVATPQDEVLLRLESPGGVVHGYGLASSQLARLRTGGIRLTVAVDKVAASGGY
HHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCHHHHHHHHCCCEEEEEEEEHHHCCCCE
MMACVADRIVAAPFAIIGSIGVVAQIPNFHRLLKKNDIDVELHTAGEFKRTLTLFGENTE
EHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEECCCCHHHHHEEECCCHH
QGREKFREDLNDTHELFKQFVHQQRPSLDIDSVATGEHWFGTQAKEKGLIDAIGTSDDLL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCEEECCCCCCEE
IAEMENHEVVGVRYARRKRMMDRFTGSAAESVDRLLLRWWQRGEKPLL
EEECCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]