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The map label for this gene is dsdX [H]

Identifier: 157370690

GI number: 157370690

Start: 2682554

End: 2683891

Strand: Reverse

Name: dsdX [H]

Synonym: Spro_2450

Alternate gene names: 157370690

Gene position: 2683891-2682554 (Counterclockwise)

Preceding gene: 157370692

Following gene: 157370688

Centisome position: 49.26

GC content: 51.87

Gene sequence:

>1338_bases
ATGGATTCGCAAGTTTGGGTTGCCGGCACGCTGATCGCCAGTATCGCGATCATCATTTTGACCATCGTGAAGTTTAAGTT
TCACCCTTTTTTGGCGTTACTGTTAGCAAGCTTCTTTGTCGGCAGCATGATGGGGATGGGCCCGATTGATATGGTCAATG
CCATCGAAAACGGCATCGGCAGTACGCTAGGTTTTTTGGCAGCGATCATTGGGCTGGGGACCATTCTGGGCAAAATGATG
GAGGTCTCCGGGGCGGCAGAGCGTATTGGTATTGCGTTGCAACGCTGCCGCTGGTTGTCTGTCGACGTGATTATGGTGCT
GGTCGGCTTGGTTTGCGGTATCACGCTGTTTGTTGAAGTGGGCGTAGTTCTGTTGATCCCATTGGCTTTCTCCATCGCCA
GAAAAACCGGGACGTCATTACTCAAGCTGGCGATTCCTTTGTGTACCGCATTGATGGCGGTGCACTGTGTGGTTCCCCCT
CATCCCGCAGCGTTATTTGTTACCAACAAACTGGGAGCCGATGTGGGCACGGTGATTGTTTATGGCCTGTTCGTCGGGCT
GACGGCGTCACTGGTAGGTGGTCCACTGTTCCTGAAATTGCTGGGTAAACGCTTGCCGTTTAAAGCGGTACCGCCTGAGT
TCTCCAATCTGGCCGTGCGAGAAGAACATTCACTGCCATCACTGGGAGCAACGCTGTTTACGGTTTTACTGCCCATAGTG
CTGATGCTGGTCAAAACGGTCGCTGAGCTGAATCTGAATAAAGAAGGGAGCTTATTTGCCGCTATGGAGTTTATCGGTAA
CCCGATCATTGCCATGTTTATTGCTGTGTTTGTGGCTTATTACGTTCTGGGGATACGTCGTCACATGGGGATGAGCGCGC
TGTTGAGCCATACTGAGTCCGGTTTCTCCTCCATTGCCAATATCTTGTTGATCATCGGGGCCGGCGGAGCGTTTAACAGT
ATTTTGAAGACCAGTGGCCTGGCCGATACCCTGGCGCTGATGCTGTCAAACCTGCATATGCATCCTATCTTGTTAGCCTG
GCTGGTCGCACTTATTCTGCATGCTGCCGTGGGTTCCGCCACCGTAGCCATGATGGGCGCCACGGCGATAGTCGCACCGA
TGTTGTCGCTTTATCCCAATGTCAGCCCGGAGATCGTGACCATTGCCATCGGTTCTGGTGCTATTGGCTGCACCATAGTG
ACGGATTCACTGTTCTGGTTGGTGAAGCAATATTGTGGAGCGACGCTGAATGAAACCTTCAAGTATTACACTACGGCCAC
CTTTATCGCTTCGGTATTGGCGCTGGGCATGACCTTCCTGCTTTCATACATTATTTGA

Upstream 100 bases:

>100_bases
TTGATTCTGTTTCACTCATGTGAGAGCGGATTTTTATCGTTTGTCACCGATCGTCGTTTTCCTGTCCAATGACAGTCAGT
TTATGACGGGGGTATGGGCT

Downstream 100 bases:

>100_bases
GTATCTTCATCGGTAATCGTCGCCAGGTGAAGTCCTGCGACGATTGCCGTTATTAAGATTGTTTTGGGTCAGAAGTGATG
CGGCGAGGACGATAAATTGC

Product: permease DsdX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MDSQVWVAGTLIASIAIIILTIVKFKFHPFLALLLASFFVGSMMGMGPIDMVNAIENGIGSTLGFLAAIIGLGTILGKMM
EVSGAAERIGIALQRCRWLSVDVIMVLVGLVCGITLFVEVGVVLLIPLAFSIARKTGTSLLKLAIPLCTALMAVHCVVPP
HPAALFVTNKLGADVGTVIVYGLFVGLTASLVGGPLFLKLLGKRLPFKAVPPEFSNLAVREEHSLPSLGATLFTVLLPIV
LMLVKTVAELNLNKEGSLFAAMEFIGNPIIAMFIAVFVAYYVLGIRRHMGMSALLSHTESGFSSIANILLIIGAGGAFNS
ILKTSGLADTLALMLSNLHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLSLYPNVSPEIVTIAIGSGAIGCTIV
TDSLFWLVKQYCGATLNETFKYYTTATFIASVLALGMTFLLSYII

Sequences:

>Translated_445_residues
MDSQVWVAGTLIASIAIIILTIVKFKFHPFLALLLASFFVGSMMGMGPIDMVNAIENGIGSTLGFLAAIIGLGTILGKMM
EVSGAAERIGIALQRCRWLSVDVIMVLVGLVCGITLFVEVGVVLLIPLAFSIARKTGTSLLKLAIPLCTALMAVHCVVPP
HPAALFVTNKLGADVGTVIVYGLFVGLTASLVGGPLFLKLLGKRLPFKAVPPEFSNLAVREEHSLPSLGATLFTVLLPIV
LMLVKTVAELNLNKEGSLFAAMEFIGNPIIAMFIAVFVAYYVLGIRRHMGMSALLSHTESGFSSIANILLIIGAGGAFNS
ILKTSGLADTLALMLSNLHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLSLYPNVSPEIVTIAIGSGAIGCTIV
TDSLFWLVKQYCGATLNETFKYYTTATFIASVLALGMTFLLSYII
>Mature_445_residues
MDSQVWVAGTLIASIAIIILTIVKFKFHPFLALLLASFFVGSMMGMGPIDMVNAIENGIGSTLGFLAAIIGLGTILGKMM
EVSGAAERIGIALQRCRWLSVDVIMVLVGLVCGITLFVEVGVVLLIPLAFSIARKTGTSLLKLAIPLCTALMAVHCVVPP
HPAALFVTNKLGADVGTVIVYGLFVGLTASLVGGPLFLKLLGKRLPFKAVPPEFSNLAVREEHSLPSLGATLFTVLLPIV
LMLVKTVAELNLNKEGSLFAAMEFIGNPIIAMFIAVFVAYYVLGIRRHMGMSALLSHTESGFSSIANILLIIGAGGAFNS
ILKTSGLADTLALMLSNLHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLSLYPNVSPEIVTIAIGSGAIGCTIV
TDSLFWLVKQYCGATLNETFKYYTTATFIASVLALGMTFLLSYII

Specific function: Probable permease for an unknown substrate [H]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI1788707, Length=445, Percent_Identity=83.8202247191011, Blast_Score=756, Evalue=0.0,
Organism=Escherichia coli, GI1790716, Length=430, Percent_Identity=35.1162790697674, Blast_Score=265, Evalue=5e-72,
Organism=Escherichia coli, GI48994935, Length=436, Percent_Identity=36.697247706422, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1790776, Length=432, Percent_Identity=32.6388888888889, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI2367370, Length=434, Percent_Identity=33.8709677419355, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI48994939, Length=419, Percent_Identity=33.6515513126492, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789097, Length=446, Percent_Identity=28.6995515695067, Blast_Score=162, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 46909; Mature: 46909

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592420; 3275618; 9205837; 9278503; 3029015; 1659648; 12218016 [H]