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The map label for this gene is hycA [H]

Identifier: 157370674

GI number: 157370674

Start: 2668024

End: 2668491

Strand: Reverse

Name: hycA [H]

Synonym: Spro_2434

Alternate gene names: 157370674

Gene position: 2668491-2668024 (Counterclockwise)

Preceding gene: 157370681

Following gene: 157370673

Centisome position: 48.97

GC content: 47.86

Gene sequence:

>468_bases
ATGAGTACAATCAGTGAAGTAACCAGTCAGGCCGATTACATCGCCAACAAAAGCAATCGTCTGATGGCACAATGGCAGAC
CTACCACAGCACTCTGGTCAAAGCGGTCACCACCACCAAAAAGAAGATTAATCATCAGTTTACCTACGGGCAGGAAAACG
ACCTGCGCTTTGTGCTGTTTAACCACTTTACGGTCAGCATCCAGTTGAGCGAAGGGTTTTACAGCCGGGATATTTGCTAC
CGGATTAATCTGGCCACGGCCCACGAGCCGGAAAACTTTGCCCCTTTCGCCCATGCCACGCTGGATGAAAACGGCAATAT
CGACGAAGTAATAAACAACCGCGACATGCAGGCGGTATTTGAACACTACCTGGATAAGATCGCCGTTATTTATCAATGCC
TGTTTGATTCCTTGCATGATGGTCACGCCATTCAAGACGCTCTGAAAAAAATAACCTTACCCGTCTGA

Upstream 100 bases:

>100_bases
AAAGGAAATAATGTAATTTACCGGAATTTGGCACGCTTTATGCTTTAACTCGCTGACCCGGAGCTATTTCGACAACGACT
ATCAATTTTGAGTGAGGACC

Downstream 100 bases:

>100_bases
TCGCAGGCGTTAATCACCGACAGAAAACTGTCGAAGCGTCATTTTTTACTGACGATTTCGTCATAAATGACGAAGCAAGG
AGTGTGCATGAACCGCTTTA

Product: formate hydrogenlyase regulatory protein HycA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MSTISEVTSQADYIANKSNRLMAQWQTYHSTLVKAVTTTKKKINHQFTYGQENDLRFVLFNHFTVSIQLSEGFYSRDICY
RINLATAHEPENFAPFAHATLDENGNIDEVINNRDMQAVFEHYLDKIAVIYQCLFDSLHDGHAIQDALKKITLPV

Sequences:

>Translated_155_residues
MSTISEVTSQADYIANKSNRLMAQWQTYHSTLVKAVTTTKKKINHQFTYGQENDLRFVLFNHFTVSIQLSEGFYSRDICY
RINLATAHEPENFAPFAHATLDENGNIDEVINNRDMQAVFEHYLDKIAVIYQCLFDSLHDGHAIQDALKKITLPV
>Mature_154_residues
STISEVTSQADYIANKSNRLMAQWQTYHSTLVKAVTTTKKKINHQFTYGQENDLRFVLFNHFTVSIQLSEGFYSRDICYR
INLATAHEPENFAPFAHATLDENGNIDEVINNRDMQAVFEHYLDKIAVIYQCLFDSLHDGHAIQDALKKITLPV

Specific function: Regulatory protein for the formate hydrogenlyase system. Could act by directly interacting with fhlA or by preventing the binding of fhlA to the upstream activatory sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789080, Length=138, Percent_Identity=36.9565217391304, Blast_Score=100, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021285 [H]

Pfam domain/function: PF11046 HycA_repressor [H]

EC number: NA

Molecular weight: Translated: 17815; Mature: 17684

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTISEVTSQADYIANKSNRLMAQWQTYHSTLVKAVTTTKKKINHQFTYGQENDLRFVLF
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
NHFTVSIQLSEGFYSRDICYRINLATAHEPENFAPFAHATLDENGNIDEVINNRDMQAVF
EEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHCCCCHHHHH
EHYLDKIAVIYQCLFDSLHDGHAIQDALKKITLPV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
STISEVTSQADYIANKSNRLMAQWQTYHSTLVKAVTTTKKKINHQFTYGQENDLRFVLF
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
NHFTVSIQLSEGFYSRDICYRINLATAHEPENFAPFAHATLDENGNIDEVINNRDMQAVF
EEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHCCCCHHHHH
EHYLDKIAVIYQCLFDSLHDGHAIQDALKKITLPV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]