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The map label for this gene is hycD [H]

Identifier: 157370671

GI number: 157370671

Start: 2664508

End: 2665443

Strand: Reverse

Name: hycD [H]

Synonym: Spro_2431

Alternate gene names: 157370671

Gene position: 2665443-2664508 (Counterclockwise)

Preceding gene: 157370672

Following gene: 157370670

Centisome position: 48.92

GC content: 61.75

Gene sequence:

>936_bases
ATGACCTATCCCTATGTGTTACTCGGTTTGCTGCAGGCTCTGCTGTTACTGGCTGTTGCCCCGCTGTTTGCCGGCATCAG
CCGGGTGCTGCGCGCCCGCATTCATACCCGACGCGGCCCCGGCGTATTACAGGAATACCGTGATATCGCCAAACTGCTGA
AGCGCCAAAGCGTGGCGCCGGGGGCTTCCGGCCTGGCTTTTCGCGCCATGCCTTACTTACTGACCGGCACCTTGCTGGCC
ATCGCCTGTGCACTGCCGATGCTGACTACCGCCTCACCGCTGCCTGCCATCGGTGATGTGATCACCCTGATCTATCTGTT
CGCCGTGGTGCGCTTTGTGTTTGCCATTGCCGGGCTGGATACCGGCAGCCCCTTCACCGCTATCGGTGCCAGCCGTGAGG
CAGTGTTAGGCATTCTGGTCGAACCGATCCTGTTGCTGGGTCTGTGGGTGACGGCGCTGGTCGCCGGTTCCACCCAACTG
AGCGCCATGGTGCAAAGCCTGCTGGGCTTGCCGCATCACGCCTGGCTGCCACTGCTGTTGGCCGGTTTGGCCTGCGCGTT
CGCCACCTATATCGAAATGGGCAAGCTGCCGTTCGACATGGCGGAAGCCGAACAAGAGCTGCAGGAAGGCCCGCTGACGG
AATATTCCGGCGTCGAGCTCGGCATTATCAAATGGGGCATCAGCCTCAAACAACTGGTGGTGCTGCAACTGTTCCTCGGC
GTGTTCCTGCCCTGGGGCCAGGCGGCACAGCTCACTGCCCCGCAGCTGCTGACTGGACTGGTGCTGGCGCTGTTCAAGCT
GTTGTGTGCGGTGGTGCTGATCGCGGTTCTCGAAAATAGCGTGGCACGTTTGCGCTTCCTCAAGACGGGCCGTACCACCT
GGGCCGGTTTTGGGCTGGCTTTTCTGGCGCTGGTTTCCTGGCTGGTCGTCGGCTGA

Upstream 100 bases:

>100_bases
GACCGGTTACACCGTAACGCATTCGTTGCCTTCTGCCGCGGTCTGGCCGCCGTAGAGTTGGCGGTGCTGCTGGTCGTGGC
TTTTGCCTGAGGAGATAACG

Downstream 100 bases:

>100_bases
ACAATGATTAAGGCAATCAATAATGACTAACGAACATCAAGGCCAGCACTATCTGGCGGCGTTGCAGCAACAATTCCCCG
CTGCCATGCTGGCGGCAGAA

Product: respiratory-chain NADH dehydrogenase subunit 1

Products: NA

Alternate protein names: FHL subunit 4; Hydrogenase 3 component D [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTYPYVLLGLLQALLLLAVAPLFAGISRVLRARIHTRRGPGVLQEYRDIAKLLKRQSVAPGASGLAFRAMPYLLTGTLLA
IACALPMLTTASPLPAIGDVITLIYLFAVVRFVFAIAGLDTGSPFTAIGASREAVLGILVEPILLLGLWVTALVAGSTQL
SAMVQSLLGLPHHAWLPLLLAGLACAFATYIEMGKLPFDMAEAEQELQEGPLTEYSGVELGIIKWGISLKQLVVLQLFLG
VFLPWGQAAQLTAPQLLTGLVLALFKLLCAVVLIAVLENSVARLRFLKTGRTTWAGFGLAFLALVSWLVVG

Sequences:

>Translated_311_residues
MTYPYVLLGLLQALLLLAVAPLFAGISRVLRARIHTRRGPGVLQEYRDIAKLLKRQSVAPGASGLAFRAMPYLLTGTLLA
IACALPMLTTASPLPAIGDVITLIYLFAVVRFVFAIAGLDTGSPFTAIGASREAVLGILVEPILLLGLWVTALVAGSTQL
SAMVQSLLGLPHHAWLPLLLAGLACAFATYIEMGKLPFDMAEAEQELQEGPLTEYSGVELGIIKWGISLKQLVVLQLFLG
VFLPWGQAAQLTAPQLLTGLVLALFKLLCAVVLIAVLENSVARLRFLKTGRTTWAGFGLAFLALVSWLVVG
>Mature_310_residues
TYPYVLLGLLQALLLLAVAPLFAGISRVLRARIHTRRGPGVLQEYRDIAKLLKRQSVAPGASGLAFRAMPYLLTGTLLAI
ACALPMLTTASPLPAIGDVITLIYLFAVVRFVFAIAGLDTGSPFTAIGASREAVLGILVEPILLLGLWVTALVAGSTQLS
AMVQSLLGLPHHAWLPLLLAGLACAFATYIEMGKLPFDMAEAEQELQEGPLTEYSGVELGIIKWGISLKQLVVLQLFLGV
FLPWGQAAQLTAPQLLTGLVLALFKLLCAVVLIAVLENSVARLRFLKTGRTTWAGFGLAFLALVSWLVVG

Specific function: Hydrogen metabolism; FHL pathway. [C]

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1789077, Length=303, Percent_Identity=66.996699669967, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI87082115, Length=304, Percent_Identity=56.9078947368421, Blast_Score=299, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: NA

Molecular weight: Translated: 33180; Mature: 33049

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYPYVLLGLLQALLLLAVAPLFAGISRVLRARIHTRRGPGVLQEYRDIAKLLKRQSVAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
GASGLAFRAMPYLLTGTLLAIACALPMLTTASPLPAIGDVITLIYLFAVVRFVFAIAGLD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TGSPFTAIGASREAVLGILVEPILLLGLWVTALVAGSTQLSAMVQSLLGLPHHAWLPLLL
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
AGLACAFATYIEMGKLPFDMAEAEQELQEGPLTEYSGVELGIIKWGISLKQLVVLQLFLG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEHHHHHCHHHHHHHHHHHHHH
VFLPWGQAAQLTAPQLLTGLVLALFKLLCAVVLIAVLENSVARLRFLKTGRTTWAGFGLA
HHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FLALVSWLVVG
HHHHHHHHHCC
>Mature Secondary Structure 
TYPYVLLGLLQALLLLAVAPLFAGISRVLRARIHTRRGPGVLQEYRDIAKLLKRQSVAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
GASGLAFRAMPYLLTGTLLAIACALPMLTTASPLPAIGDVITLIYLFAVVRFVFAIAGLD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TGSPFTAIGASREAVLGILVEPILLLGLWVTALVAGSTQLSAMVQSLLGLPHHAWLPLLL
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
AGLACAFATYIEMGKLPFDMAEAEQELQEGPLTEYSGVELGIIKWGISLKQLVVLQLFLG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEHHHHHCHHHHHHHHHHHHHH
VFLPWGQAAQLTAPQLLTGLVLALFKLLCAVVLIAVLENSVARLRFLKTGRTTWAGFGLA
HHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FLALVSWLVVG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2187144; 9278503 [H]