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The map label for this gene is hoxN [H]

Identifier: 157370662

GI number: 157370662

Start: 2654251

End: 2655282

Strand: Reverse

Name: hoxN [H]

Synonym: Spro_2422

Alternate gene names: 157370662

Gene position: 2655282-2654251 (Counterclockwise)

Preceding gene: 157370663

Following gene: 157370661

Centisome position: 48.73

GC content: 55.43

Gene sequence:

>1032_bases
ATGGTAAACCGCGAGTTTTTCCACACCCATACCCGCGCCTTTTGGCTATTACTGGCGCTGGTGGCGCTAAACCTGTTGGC
CTGGGGAGCGGCTTTTGCCGCATTCCATCACTACCCGGCGTTAATCGCTGCCGCTTTGCTGGCTTATGGCTACGGGCTGC
GTCATGCGGTAGATGCCGATCATATCGCCGCTATTGATAACGTCACCCGCAAACTGATGCAGCAAGGCCAGCGCCCGGTT
TCCGTCGGCGCATTCTTCTCTTTGGGCCACTCCAGCATTGTGATCCTGGCCTGCATCGCCATTGCCGCCACTTCATTGGC
ATTTGGCGATCGTATTGGCTGGCTGCATCAGTACGGCGCGACACTGGGCACGCTGATCTCCTCGCTGTTCCTGTTGGCCA
TGGCACTATTGAACTGGCTGATTTTCCGAGACGTTTACCGAATTTTCCGCCAGGTGAAACGCGGGGAAAAACTGGTGGAA
CAAGATGTCGCCCTGCTGGTTAACGGGAGCGGCGGCGTGATGACACGTCTGTATCGCTTCGCTTTTAATCTGGTGAATAA
AAGCTGGCATATGTATCTGGTCGGCTTTTTATTTGGCCTGGGTTTTGACACCGCCACCGAAGTCGGCCTGTTGGGCATCT
CCGCGGCCGGTGCCACTTCCGGCCTGTCGGTCTGGTCGATTATGCTGTTCCCGTTGCTGTTCGCCAGCGGCATGGCGTTG
ATTGACTCGCTGGATAATTTTGTGATGGTTGGCGCTTATGGCTGGGCCTTCAATAAACCGATCCGCAAGCTGTATTACAA
CATGACCATTACCGCTACCAGCGTGGCTATTGCTCTGGTGATCGGTGGCCTGGAAGGTTTGGGGTTGTTGGTCGACAAAC
TTGGGTTACAAGGCGGGCTGTGGCGCGGTGTTGAAGTCCTCAATGACCATATGGGTAGCGTGGGTTACGCCGCTATCGCA
TTATTTGTGGTGCTGTGGGCGTTGTCCGCGCTGAATTACCGCCGCAAAAACTATGACTCGCTGACCCTCTAG

Upstream 100 bases:

>100_bases
CAACTGCCTGCAGGTGATGGCGGGCTGGCGCTTGGCCAGGCGCTGGTCGCTTGCGCCCAACATTCTCCGGCTTCTTCTTC
CACCTTTGACAGGACCTGAC

Downstream 100 bases:

>100_bases
TCCCCTTACCGGCAGCCACCGAGGCTGCCGGTAAAAAACACTGCATTGGTTATTAAATCCTTTCAGTTAATATTATAACC
CAGGATATTAATCAATCTGC

Product: high-affinity nickel-transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MVNREFFHTHTRAFWLLLALVALNLLAWGAAFAAFHHYPALIAAALLAYGYGLRHAVDADHIAAIDNVTRKLMQQGQRPV
SVGAFFSLGHSSIVILACIAIAATSLAFGDRIGWLHQYGATLGTLISSLFLLAMALLNWLIFRDVYRIFRQVKRGEKLVE
QDVALLVNGSGGVMTRLYRFAFNLVNKSWHMYLVGFLFGLGFDTATEVGLLGISAAGATSGLSVWSIMLFPLLFASGMAL
IDSLDNFVMVGAYGWAFNKPIRKLYYNMTITATSVAIALVIGGLEGLGLLVDKLGLQGGLWRGVEVLNDHMGSVGYAAIA
LFVVLWALSALNYRRKNYDSLTL

Sequences:

>Translated_343_residues
MVNREFFHTHTRAFWLLLALVALNLLAWGAAFAAFHHYPALIAAALLAYGYGLRHAVDADHIAAIDNVTRKLMQQGQRPV
SVGAFFSLGHSSIVILACIAIAATSLAFGDRIGWLHQYGATLGTLISSLFLLAMALLNWLIFRDVYRIFRQVKRGEKLVE
QDVALLVNGSGGVMTRLYRFAFNLVNKSWHMYLVGFLFGLGFDTATEVGLLGISAAGATSGLSVWSIMLFPLLFASGMAL
IDSLDNFVMVGAYGWAFNKPIRKLYYNMTITATSVAIALVIGGLEGLGLLVDKLGLQGGLWRGVEVLNDHMGSVGYAAIA
LFVVLWALSALNYRRKNYDSLTL
>Mature_343_residues
MVNREFFHTHTRAFWLLLALVALNLLAWGAAFAAFHHYPALIAAALLAYGYGLRHAVDADHIAAIDNVTRKLMQQGQRPV
SVGAFFSLGHSSIVILACIAIAATSLAFGDRIGWLHQYGATLGTLISSLFLLAMALLNWLIFRDVYRIFRQVKRGEKLVE
QDVALLVNGSGGVMTRLYRFAFNLVNKSWHMYLVGFLFGLGFDTATEVGLLGISAAGATSGLSVWSIMLFPLLFASGMAL
IDSLDNFVMVGAYGWAFNKPIRKLYYNMTITATSVAIALVIGGLEGLGLLVDKLGLQGGLWRGVEVLNDHMGSVGYAAIA
LFVVLWALSALNYRRKNYDSLTL

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 37443; Mature: 37443

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNREFFHTHTRAFWLLLALVALNLLAWGAAFAAFHHYPALIAAALLAYGYGLRHAVDAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHH
HIAAIDNVTRKLMQQGQRPVSVGAFFSLGHSSIVILACIAIAATSLAFGDRIGWLHQYGA
HHHHHHHHHHHHHHCCCCCEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGTLISSLFLLAMALLNWLIFRDVYRIFRQVKRGEKLVEQDVALLVNGSGGVMTRLYRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHH
AFNLVNKSWHMYLVGFLFGLGFDTATEVGLLGISAAGATSGLSVWSIMLFPLLFASGMAL
HHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHH
IDSLDNFVMVGAYGWAFNKPIRKLYYNMTITATSVAIALVIGGLEGLGLLVDKLGLQGGL
HHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCH
WRGVEVLNDHMGSVGYAAIALFVVLWALSALNYRRKNYDSLTL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVNREFFHTHTRAFWLLLALVALNLLAWGAAFAAFHHYPALIAAALLAYGYGLRHAVDAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHH
HIAAIDNVTRKLMQQGQRPVSVGAFFSLGHSSIVILACIAIAATSLAFGDRIGWLHQYGA
HHHHHHHHHHHHHHCCCCCEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGTLISSLFLLAMALLNWLIFRDVYRIFRQVKRGEKLVEQDVALLVNGSGGVMTRLYRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHH
AFNLVNKSWHMYLVGFLFGLGFDTATEVGLLGISAAGATSGLSVWSIMLFPLLFASGMAL
HHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHH
IDSLDNFVMVGAYGWAFNKPIRKLYYNMTITATSVAIALVIGGLEGLGLLVDKLGLQGGL
HHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCH
WRGVEVLNDHMGSVGYAAIALFVVLWALSALNYRRKNYDSLTL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]