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The map label for this gene is ddc [H]

Identifier: 157370658

GI number: 157370658

Start: 2647945

End: 2649417

Strand: Reverse

Name: ddc [H]

Synonym: Spro_2418

Alternate gene names: 157370658

Gene position: 2649417-2647945 (Counterclockwise)

Preceding gene: 157370659

Following gene: 157370657

Centisome position: 48.62

GC content: 56.14

Gene sequence:

>1473_bases
ATGTCCCGGTTAAACCCGATTCTGGCCGCTTCGGCGCAAAGCACCGAAGCCTACCAGCAAGCGATCGAGCAAAGCAGCCA
GGCGGTAGTGCAGTGGCTGCAACAACCCGAGATGTATCAGGGGAAAACCGTTGCCGAATTGCGTGAACGCATTACGCTTG
ATTTTAATCCGCAGGGCCTGGGCAACCAGGCGGCGATCGAACGCGCGATTGAGTACTTTTTAAAAGACAGCCTGTCGGTA
CATCACCCACAGTGCGTCGCGCATTTGCATTGCCCAAGCCTGGTGATTAGCCAGGCCGCGGAAGTGCTGATCAACGCCAC
CAACCAGAGCATGGACTCCTGGGATCAAAGCCCGTCAGCCACCATCATCGAGATGAAGCTGATTGAGTGGTTGCGTACCC
AGGTCGGTTATCAGCCTGGCGATGCGGGCGTGTTCACCAGCGGCGGTACCCAGAGTAATCTGATGGGCCTGATGCTGGCT
CGCGATGCCTTCTTCGCCAAACAGGGCCACTCTGTGCAACAGGATGGCCTGGTCGGTAACCTGCGCAAGATTAAAGTCTT
ATGTTCTGAGAATGCTCATTTCTCGGTGCAAAAGAACATGGCGTTGCTCGGCCTGGGTTATCAATCCGTGACGCTGGTGA
AAACCGATCAATTCGCACGAATGGATGTGAACGACCTGGCCGAAAAACTGGCGCAAGCCCAGGCCAATGGCGAACAGATC
CTGGCGATCGTCGCCACCGCTGGCACCACCGATGCCGGAGCTATCGACCCGCTGCGTGCGATTGCGCAGTTGGCGGCAGA
ACACCAGATCTGGGTGCATGTTGATGCGGCATGGGGTGGCGCGTTGCTGCTTTCCGAGAAGTACCGTGACTATCTGGACG
GCATTGAATTAGTGGATTCCATTACCCTGGACTTCCATAAACAGTTCTTCCAGACCATCAGTTGCGGCGCCTTCTTGCTG
AAAGAAGCCCGTCACTATGAGCTGATGCGCTATCAGGCGGCCTACCTGAACTCCGAATTCGACGAAGCTCAGGGCGTGCC
TAACCTGGTGTCCAAATCCTTGCAGACCACCCGCCGTTTTGACGCGTTAAAACTGTGGATGGGGCTGGAGGCATTAGGGC
AACAGCAATATGCTGCGATCATCGATCACGGCGTGACGCTGGCACAACAGGTTGCTCACTATATCGGCGACCAACCGGCG
CTGGAACTGGTGATGCAACCGCAGTTGGCCAGTGTGCTGTTCCGTTACCGTCCGCAGTCATTAGCCGCCAGCAGCGATGC
CGCAGTAGCACTGCTGAACCAGCGAATTGGTGATGCATTGCTGGAGTCAGGACGTGCCAACGTCGGGGTGACCGAATTTA
ATGGCGTAACCTGCCTGAAAATGACGTTGTTAAACCCAACGGTCAGCCTGGACGATATCAAAGTCCTGCTGGCACTGGTG
GAAAAAACCGCGCAGCAGTTGCCTGCCGCCTAA

Upstream 100 bases:

>100_bases
CACTGTTGATCACCAACGACGAACTGGGCATTTTCCTGGATAAATTTGAACAGGCCCTGTTAGCCGCCGGCGTCAAGCCT
GTAGGTATGGAGTGAATTCG

Downstream 100 bases:

>100_bases
TCCACCTGCCCTGACCGGCAGCCAAAAGCCGATAGCCTTTACGGGTTATCGGCTTTTTTGCACCAGACGCCTTCCCTTAT
TGCCTGCTCAGGATGCCCGA

Product: pyridoxal-dependent decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSRLNPILAASAQSTEAYQQAIEQSSQAVVQWLQQPEMYQGKTVAELRERITLDFNPQGLGNQAAIERAIEYFLKDSLSV
HHPQCVAHLHCPSLVISQAAEVLINATNQSMDSWDQSPSATIIEMKLIEWLRTQVGYQPGDAGVFTSGGTQSNLMGLMLA
RDAFFAKQGHSVQQDGLVGNLRKIKVLCSENAHFSVQKNMALLGLGYQSVTLVKTDQFARMDVNDLAEKLAQAQANGEQI
LAIVATAGTTDAGAIDPLRAIAQLAAEHQIWVHVDAAWGGALLLSEKYRDYLDGIELVDSITLDFHKQFFQTISCGAFLL
KEARHYELMRYQAAYLNSEFDEAQGVPNLVSKSLQTTRRFDALKLWMGLEALGQQQYAAIIDHGVTLAQQVAHYIGDQPA
LELVMQPQLASVLFRYRPQSLAASSDAAVALLNQRIGDALLESGRANVGVTEFNGVTCLKMTLLNPTVSLDDIKVLLALV
EKTAQQLPAA

Sequences:

>Translated_490_residues
MSRLNPILAASAQSTEAYQQAIEQSSQAVVQWLQQPEMYQGKTVAELRERITLDFNPQGLGNQAAIERAIEYFLKDSLSV
HHPQCVAHLHCPSLVISQAAEVLINATNQSMDSWDQSPSATIIEMKLIEWLRTQVGYQPGDAGVFTSGGTQSNLMGLMLA
RDAFFAKQGHSVQQDGLVGNLRKIKVLCSENAHFSVQKNMALLGLGYQSVTLVKTDQFARMDVNDLAEKLAQAQANGEQI
LAIVATAGTTDAGAIDPLRAIAQLAAEHQIWVHVDAAWGGALLLSEKYRDYLDGIELVDSITLDFHKQFFQTISCGAFLL
KEARHYELMRYQAAYLNSEFDEAQGVPNLVSKSLQTTRRFDALKLWMGLEALGQQQYAAIIDHGVTLAQQVAHYIGDQPA
LELVMQPQLASVLFRYRPQSLAASSDAAVALLNQRIGDALLESGRANVGVTEFNGVTCLKMTLLNPTVSLDDIKVLLALV
EKTAQQLPAA
>Mature_489_residues
SRLNPILAASAQSTEAYQQAIEQSSQAVVQWLQQPEMYQGKTVAELRERITLDFNPQGLGNQAAIERAIEYFLKDSLSVH
HPQCVAHLHCPSLVISQAAEVLINATNQSMDSWDQSPSATIIEMKLIEWLRTQVGYQPGDAGVFTSGGTQSNLMGLMLAR
DAFFAKQGHSVQQDGLVGNLRKIKVLCSENAHFSVQKNMALLGLGYQSVTLVKTDQFARMDVNDLAEKLAQAQANGEQIL
AIVATAGTTDAGAIDPLRAIAQLAAEHQIWVHVDAAWGGALLLSEKYRDYLDGIELVDSITLDFHKQFFQTISCGAFLLK
EARHYELMRYQAAYLNSEFDEAQGVPNLVSKSLQTTRRFDALKLWMGLEALGQQQYAAIIDHGVTLAQQVAHYIGDQPAL
ELVMQPQLASVLFRYRPQSLAASSDAAVALLNQRIGDALLESGRANVGVTEFNGVTCLKMTLLNPTVSLDDIKVLLALVE
KTAQQLPAA

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI194294551, Length=471, Percent_Identity=30.1486199575372, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI197276620, Length=424, Percent_Identity=30.4245283018868, Blast_Score=203, Evalue=4e-52,
Organism=Homo sapiens, GI4503875, Length=424, Percent_Identity=30.4245283018868, Blast_Score=203, Evalue=4e-52,
Organism=Homo sapiens, GI197383062, Length=409, Percent_Identity=30.3178484107579, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI58331246, Length=427, Percent_Identity=29.7423887587822, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI92110055, Length=358, Percent_Identity=26.2569832402235, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4503281, Length=368, Percent_Identity=25, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI132814448, Length=368, Percent_Identity=25, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71993062, Length=443, Percent_Identity=25.9593679458239, Blast_Score=172, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17555682, Length=435, Percent_Identity=26.2068965517241, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71993058, Length=363, Percent_Identity=28.3746556473829, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17534817, Length=501, Percent_Identity=22.3552894211577, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17534819, Length=501, Percent_Identity=22.3552894211577, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71981211, Length=460, Percent_Identity=23.4782608695652, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71981217, Length=469, Percent_Identity=23.0277185501066, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17551992, Length=457, Percent_Identity=22.3194748358862, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI133931025, Length=377, Percent_Identity=21.4854111405836, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17136594, Length=410, Percent_Identity=29.2682926829268, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21356415, Length=390, Percent_Identity=30.7692307692308, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24657193, Length=382, Percent_Identity=28.0104712041885, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24657185, Length=382, Percent_Identity=28.0104712041885, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24657188, Length=382, Percent_Identity=28.0104712041885, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24652373, Length=401, Percent_Identity=26.1845386533666, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI221476190, Length=435, Percent_Identity=25.2873563218391, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24585143, Length=435, Percent_Identity=25.2873563218391, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24585139, Length=435, Percent_Identity=25.2873563218391, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24585135, Length=327, Percent_Identity=24.1590214067278, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17136190, Length=362, Percent_Identity=22.9281767955801, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24586044, Length=352, Percent_Identity=24.7159090909091, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI28573972, Length=407, Percent_Identity=24.0786240786241, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 53636; Mature: 53505

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLNPILAASAQSTEAYQQAIEQSSQAVVQWLQQPEMYQGKTVAELRERITLDFNPQGL
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEECCCCCCC
GNQAAIERAIEYFLKDSLSVHHPQCVAHLHCPSLVISQAAEVLINATNQSMDSWDQSPSA
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
TIIEMKLIEWLRTQVGYQPGDAGVFTSGGTQSNLMGLMLARDAFFAKQGHSVQQDGLVGN
EEHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LRKIKVLCSENAHFSVQKNMALLGLGYQSVTLVKTDQFARMDVNDLAEKLAQAQANGEQI
HHHEEEEECCCCCEEEECCEEEEECCCCEEEEEECCCHHCCCHHHHHHHHHHHHCCCCEE
LAIVATAGTTDAGAIDPLRAIAQLAAEHQIWVHVDAAWGGALLLSEKYRDYLDGIELVDS
EEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
ITLDFHKQFFQTISCGAFLLKEARHYELMRYQAAYLNSEFDEAQGVPNLVSKSLQTTRRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHH
DALKLWMGLEALGQQQYAAIIDHGVTLAQQVAHYIGDQPALELVMQPQLASVLFRYRPQS
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHCCHH
LAASSDAAVALLNQRIGDALLESGRANVGVTEFNGVTCLKMTLLNPTVSLDDIKVLLALV
HCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEEEECCCCCCHHHHHHHHHHH
EKTAQQLPAA
HHHHHHCCCC
>Mature Secondary Structure 
SRLNPILAASAQSTEAYQQAIEQSSQAVVQWLQQPEMYQGKTVAELRERITLDFNPQGL
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEECCCCCCC
GNQAAIERAIEYFLKDSLSVHHPQCVAHLHCPSLVISQAAEVLINATNQSMDSWDQSPSA
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
TIIEMKLIEWLRTQVGYQPGDAGVFTSGGTQSNLMGLMLARDAFFAKQGHSVQQDGLVGN
EEHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LRKIKVLCSENAHFSVQKNMALLGLGYQSVTLVKTDQFARMDVNDLAEKLAQAQANGEQI
HHHEEEEECCCCCEEEECCEEEEECCCCEEEEEECCCHHCCCHHHHHHHHHHHHCCCCEE
LAIVATAGTTDAGAIDPLRAIAQLAAEHQIWVHVDAAWGGALLLSEKYRDYLDGIELVDS
EEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
ITLDFHKQFFQTISCGAFLLKEARHYELMRYQAAYLNSEFDEAQGVPNLVSKSLQTTRRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHH
DALKLWMGLEALGQQQYAAIIDHGVTLAQQVAHYIGDQPALELVMQPQLASVLFRYRPQS
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHCCHH
LAASSDAAVALLNQRIGDALLESGRANVGVTEFNGVTCLKMTLLNPTVSLDDIKVLLALV
HCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEEEECCCCCCHHHHHHHHHHH
EKTAQQLPAA
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8772175 [H]