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The map label for this gene is dat [H]

Identifier: 157370659

GI number: 157370659

Start: 2649423

End: 2650817

Strand: Reverse

Name: dat [H]

Synonym: Spro_2419

Alternate gene names: 157370659

Gene position: 2650817-2649423 (Counterclockwise)

Preceding gene: 157370661

Following gene: 157370658

Centisome position: 48.65

GC content: 54.27

Gene sequence:

>1395_bases
ATGATGACGGATAAAGTCCGTATTGATAATTTCGGTGTGAATTTAGAAAATGTAAACAACGAAACATATTTGGCGAGACA
AGCCGAATTTGAATCGAATGTCAGGAGTTACCCCCGTAAATTGCCGTTGGCAATTGCGAAAGCCCAAGGCGTGTGGATCA
CCGATGTTGAGAATAATCAATATCTTGATTGCCTGGCTGGTGCGGGTACGCTGGCTCTGGGTCATAACCATCCTGACATC
CTCCAAAGCATCCAAAATGTCATTACCAGCGGCTTGCCGTTACATACCCTCGATCTTACAACGCCGTTGAAAGATCAGTT
CTCAGCTTATTTGCTCTCTTTATTGCCAGGACAGGGCCAGGAATACTGCCTGCAGTTCTGTGGCCCTTCGGGCGCAGACG
CGGTTGAAGCCGCTCTGAAACTGGCGAAAAAGCACACCGGCCGTTCTGGCGTGATCAGCTTCTCCGGCGGCTATCATGGC
ATGACCCATGGCGCATTGGCGGTTACAGGCAACCTGTCACCGAAAGAAGCGATTAACGGCATGATGCCGGAAGTCCAGTT
TATGCCTTACCCGCATGAGTACCGCTGCCCGTTGGGTATCGGCGGCGAAGCCGGCGTTAAGGCACTGACCTACTATTTTG
AAAACCTGATTAATGACGTCGAAAGCGGCGTGCGCAAACCTGCGGCAGTCATCCTGGAAGCGGTTCAGGGTGAAGGCGGC
GTCAACCCGGCGCCGGTCGAATGGTTGCAGCGCATTCGCAAGGTCACTCAGGAACACGGCATTCTGCTGATTATCGACGA
AGTTCAAGCCGGCTTTGCCCGTACGGGTAAACTGTTCGCCTTCGAACACGCCGGTATTGAGCCGGACATCATCGTGATGT
CCAAAGCGGTGGGCGGCGGCTTGCCGTTGGCCGTTCTGGGTATCAAGAAAGAATTTGACGCCTGGGAACCTGGCCACCAT
ACCGGCACCTTCCGCGGTAACCAACTGGCGATGGCCACCGGCCTGACTACCCTGCAGCATCTTAAAGACCACAACGTGGC
CGGTAAGGTCGCCGCACAAGGCGAATGGCTGAAAGCCAAACTGGCCGAGCTGCAAAAACGTTATCCGGCCATTGGCCACG
TGCGCGGCCTGGGCTTGATGATCGGCATGGAAATCGTTAAACCAGGTGAAGCCCAGGATCATATGGGTTGTTACCCAGCG
GACCCGCAATTGTCTGCCCTGCTGCAGAAGAAATGTTTCGAAGCCGAGTTGATCCTGGAGCGTGGCGGCCGTAACGGCAA
CGTACTGCGTCTGCTGCCTTCACTGTTGATCACCAACGACGAACTGGGCATTTTCCTGGATAAATTTGAACAGGCCCTGT
TAGCCGCCGGCGTCAAGCCTGTAGGTATGGAGTGA

Upstream 100 bases:

>100_bases
GTAAAAAGCCATATATTGGGCGCGTTTTTTCACGGTAGTTACTTATTCATTTTAATAATTCAACTAGGGCGTTACTGATA
CCCCCAGTTGTAGGAGAGAT

Downstream 100 bases:

>100_bases
ATTCGATGTCCCGGTTAAACCCGATTCTGGCCGCTTCGGCGCAAAGCACCGAAGCCTACCAGCAAGCGATCGAGCAAAGC
AGCCAGGCGGTAGTGCAGTG

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MMTDKVRIDNFGVNLENVNNETYLARQAEFESNVRSYPRKLPLAIAKAQGVWITDVENNQYLDCLAGAGTLALGHNHPDI
LQSIQNVITSGLPLHTLDLTTPLKDQFSAYLLSLLPGQGQEYCLQFCGPSGADAVEAALKLAKKHTGRSGVISFSGGYHG
MTHGALAVTGNLSPKEAINGMMPEVQFMPYPHEYRCPLGIGGEAGVKALTYYFENLINDVESGVRKPAAVILEAVQGEGG
VNPAPVEWLQRIRKVTQEHGILLIIDEVQAGFARTGKLFAFEHAGIEPDIIVMSKAVGGGLPLAVLGIKKEFDAWEPGHH
TGTFRGNQLAMATGLTTLQHLKDHNVAGKVAAQGEWLKAKLAELQKRYPAIGHVRGLGLMIGMEIVKPGEAQDHMGCYPA
DPQLSALLQKKCFEAELILERGGRNGNVLRLLPSLLITNDELGIFLDKFEQALLAAGVKPVGME

Sequences:

>Translated_464_residues
MMTDKVRIDNFGVNLENVNNETYLARQAEFESNVRSYPRKLPLAIAKAQGVWITDVENNQYLDCLAGAGTLALGHNHPDI
LQSIQNVITSGLPLHTLDLTTPLKDQFSAYLLSLLPGQGQEYCLQFCGPSGADAVEAALKLAKKHTGRSGVISFSGGYHG
MTHGALAVTGNLSPKEAINGMMPEVQFMPYPHEYRCPLGIGGEAGVKALTYYFENLINDVESGVRKPAAVILEAVQGEGG
VNPAPVEWLQRIRKVTQEHGILLIIDEVQAGFARTGKLFAFEHAGIEPDIIVMSKAVGGGLPLAVLGIKKEFDAWEPGHH
TGTFRGNQLAMATGLTTLQHLKDHNVAGKVAAQGEWLKAKLAELQKRYPAIGHVRGLGLMIGMEIVKPGEAQDHMGCYPA
DPQLSALLQKKCFEAELILERGGRNGNVLRLLPSLLITNDELGIFLDKFEQALLAAGVKPVGME
>Mature_464_residues
MMTDKVRIDNFGVNLENVNNETYLARQAEFESNVRSYPRKLPLAIAKAQGVWITDVENNQYLDCLAGAGTLALGHNHPDI
LQSIQNVITSGLPLHTLDLTTPLKDQFSAYLLSLLPGQGQEYCLQFCGPSGADAVEAALKLAKKHTGRSGVISFSGGYHG
MTHGALAVTGNLSPKEAINGMMPEVQFMPYPHEYRCPLGIGGEAGVKALTYYFENLINDVESGVRKPAAVILEAVQGEGG
VNPAPVEWLQRIRKVTQEHGILLIIDEVQAGFARTGKLFAFEHAGIEPDIIVMSKAVGGGLPLAVLGIKKEFDAWEPGHH
TGTFRGNQLAMATGLTTLQHLKDHNVAGKVAAQGEWLKAKLAELQKRYPAIGHVRGLGLMIGMEIVKPGEAQDHMGCYPA
DPQLSALLQKKCFEAELILERGGRNGNVLRLLPSLLITNDELGIFLDKFEQALLAAGVKPVGME

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=438, Percent_Identity=28.9954337899543, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI37574042, Length=425, Percent_Identity=28, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI226442705, Length=423, Percent_Identity=26.7139479905437, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI24119277, Length=446, Percent_Identity=26.6816143497758, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI226442709, Length=394, Percent_Identity=27.6649746192893, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI4557809, Length=441, Percent_Identity=24.7165532879819, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI284507298, Length=338, Percent_Identity=25.7396449704142, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI188536080, Length=447, Percent_Identity=24.3847874720358, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI38679950, Length=447, Percent_Identity=24.3847874720358, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI38679946, Length=447, Percent_Identity=24.3847874720358, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1787560, Length=411, Percent_Identity=36.0097323600973, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI1789016, Length=416, Percent_Identity=35.0961538461538, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI145693181, Length=414, Percent_Identity=30.9178743961353, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1788044, Length=419, Percent_Identity=29.1169451073986, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1789759, Length=418, Percent_Identity=27.511961722488, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1786349, Length=310, Percent_Identity=30, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786991, Length=358, Percent_Identity=31.0055865921788, Blast_Score=115, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=29.8165137614679, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=450, Percent_Identity=27.7777777777778, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI25144271, Length=415, Percent_Identity=26.7469879518072, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI25144274, Length=243, Percent_Identity=30.4526748971193, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17541228, Length=448, Percent_Identity=24.3303571428571, Blast_Score=92, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=439, Percent_Identity=30.0683371298405, Blast_Score=174, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6323470, Length=421, Percent_Identity=27.790973871734, Blast_Score=149, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6321456, Length=369, Percent_Identity=27.6422764227642, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI161085790, Length=450, Percent_Identity=29.3333333333333, Blast_Score=178, Evalue=8e-45,
Organism=Drosophila melanogaster, GI28574759, Length=435, Percent_Identity=30.1149425287356, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21357415, Length=432, Percent_Identity=25.2314814814815, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356575, Length=453, Percent_Identity=26.2693156732892, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI281366494, Length=446, Percent_Identity=23.3183856502242, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24667139, Length=446, Percent_Identity=23.3183856502242, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24667143, Length=446, Percent_Identity=23.3183856502242, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 50149; Mature: 50149

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTDKVRIDNFGVNLENVNNETYLARQAEFESNVRSYPRKLPLAIAKAQGVWITDVENNQ
CCCCEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHCHHHCCEEEEECCCEEEEECCCCC
YLDCLAGAGTLALGHNHPDILQSIQNVITSGLPLHTLDLTTPLKDQFSAYLLSLLPGQGQ
EEEHCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCH
EYCLQFCGPSGADAVEAALKLAKKHTGRSGVISFSGGYHGMTHGALAVTGNLSPKEAING
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHCC
MMPEVQFMPYPHEYRCPLGIGGEAGVKALTYYFENLINDVESGVRKPAAVILEAVQGEGG
CCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
VNPAPVEWLQRIRKVTQEHGILLIIDEVQAGFARTGKLFAFEHAGIEPDIIVMSKAVGGG
CCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHCCCEEEEECCCCCCCEEEEEECCCCC
LPLAVLGIKKEFDAWEPGHHTGTFRGNQLAMATGLTTLQHLKDHNVAGKVAAQGEWLKAK
CCEEEEEEHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCEECCCCHHHHHH
LAELQKRYPAIGHVRGLGLMIGMEIVKPGEAQDHMGCYPADPQLSALLQKKCFEAELILE
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RGGRNGNVLRLLPSLLITNDELGIFLDKFEQALLAAGVKPVGME
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MMTDKVRIDNFGVNLENVNNETYLARQAEFESNVRSYPRKLPLAIAKAQGVWITDVENNQ
CCCCEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHCHHHCCEEEEECCCEEEEECCCCC
YLDCLAGAGTLALGHNHPDILQSIQNVITSGLPLHTLDLTTPLKDQFSAYLLSLLPGQGQ
EEEHCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCH
EYCLQFCGPSGADAVEAALKLAKKHTGRSGVISFSGGYHGMTHGALAVTGNLSPKEAING
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHCC
MMPEVQFMPYPHEYRCPLGIGGEAGVKALTYYFENLINDVESGVRKPAAVILEAVQGEGG
CCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
VNPAPVEWLQRIRKVTQEHGILLIIDEVQAGFARTGKLFAFEHAGIEPDIIVMSKAVGGG
CCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHCCCEEEEECCCCCCCEEEEEECCCCC
LPLAVLGIKKEFDAWEPGHHTGTFRGNQLAMATGLTTLQHLKDHNVAGKVAAQGEWLKAK
CCEEEEEEHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCEECCCCHHHHHH
LAELQKRYPAIGHVRGLGLMIGMEIVKPGEAQDHMGCYPADPQLSALLQKKCFEAELILE
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RGGRNGNVLRLLPSLLITNDELGIFLDKFEQALLAAGVKPVGME
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9260954 [H]