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The map label for this gene is stc [H]

Identifier: 157370632

GI number: 157370632

Start: 2612844

End: 2614802

Strand: Reverse

Name: stc [H]

Synonym: Spro_2392

Alternate gene names: 157370632

Gene position: 2614802-2612844 (Counterclockwise)

Preceding gene: 157370640

Following gene: 157370631

Centisome position: 47.99

GC content: 58.6

Gene sequence:

>1959_bases
ATGCCTACCGCCGCAGACCTGCTGCCAATCAAAGATGAGAGCGATCCGATTTTCAGCCTGCCGGAAGGGCCGGAGGCCGG
TGAATGGGACAGCCTGTTTTGGCAAGGCTGGCAGGCATTTAACGAAGGGAGTCAACCGGGCTGGATACGCAAGTCAATCC
TGCAATCCTGGCGGCGCTCGCGTGAGTACGGTATTGATCCTGATGAGTTTGTCTATCACGCACCGCCGGCAGAACAACTA
CAGGCCATCCTGTTGCACAACACCGGGCTGATTAGCGTGGCGCGCAGCATCATGGAAAATCTGTTGGCCTATAATCCCGA
CGGCCATATCAATCTGACCGATGCCCACGGCGTTACCCTTCACTACTGCGGTGCGGACATGACGCCGGTCGGCAGTATTC
TGCGTGAAGAGGTTCAGGGCACCAATTGCACCGCACGCTGCCTGCTGGAACAGCGACTGGTGTATGTGTTAAGCGGCGAA
AACTGGAAGATGGGGCTGCGCCAGCGTCATCGCCAGTGTGCCGCCGCACCGGTACGTAACGCCGAGGGAGTGATGATTGG
CGTGCTGACCCTCACCGCTACGCCGGATAATTTCAATGCCCACACGCTGGGCACCGTGCAGGCAGCGGCGGAGGCCGTCG
GTCAACAGCTCAAGCTGCAGCAACTCCTGGCAGAACAGCAGTCCATTCTGGAAACCCTGAATGAAGGCGTGATGGTTTGC
GATCGCCAGGGCCGTCTGAAAACCGTTAATCGCTATGCGCGCCAGATTTTTGACGGTCTGGAGCCGGGCAACAAATCAAT
CGATGAGCTGCTGCGCCCGCAGTCCGGCTCGCTGCTGGCCATGCCATTTTGTAACGATCGTGAAATGGTATTTATGCCAG
CCGGTAAACCGGCCCTCTCCTGCGTCATTTCATTGATGCCTGCGCCGGATGACGGTCGGGTGCTTTCAGTACGTGAGAAT
CAGCGTATCCGTGCCATTACTCGCCGCGTCATGGGGGTTAGCGCCAGTTATACCTTTGAGATGATATATGGCCACTCCAG
CCGTATGCGCGAGGCGATCATGCAGGCGCGCACCTGCAGTCGCAGTGACAGCACGGTATTGTTGACCGGCGAAAGCGGCA
CCGGCAAGGAGCTGTTTGCCCAGGCAATCCACAATGCTGGCGGACGTTGCAACGAGCCCTTTGTCGCCGTCAACTGCGGT
GCCTTACCGCGCGATTTGGTGCAGAGCGAGCTGTTTGGTTATGTGGACGGTGCCTTTACCGGTTCGCGCCGAGGGGGAGC
CGCCGGCAAGTTCGAACTGGCGGACGGGGGCACCCTGCTGCTGGATGAAATTGGTGAAATGCCGCTGGAAGCCCAAACCA
GCCTGCTGCGCGTGCTGCAGGAAAGCGAAGTGTTGCGCATTGGTGCGGCGCAGCCGGTAAAAGTGAATGTGCGCATCATT
GCCGCCACCCATTGCGACCTGGTGCAGGCGGTGGAGACAGGCGCGTTTCGCCGCGATCTCTATTACCGTTTGAACGTGCT
CTCGATCCCGGTTCCGCCGCTGCGTGAACGTCGGGACGACATCGCCGGTCTGGTCAACGGCTTTATTCACAAGCTTAGTG
CGCGGATGAAAAAAGTCCCACCGCAGGTTTCGCCAACGGCGATGGCCTGCCTCAACGCCTGGCATTGGCCGGGCAACGTG
CGCGAACTGGAAAACCTGGTGGAGCGGATGGTAAACCTGTGTGAAGGATTACTGATTGATCTAGGCGACCTGCCCGAGGA
TATTCGCCGCATTGCGCCTGAACCGGCCCCGCTCCCCTCCAGCCGGTTGGAAGACCATGAGCGCATACATATCATTCAGG
TCATTGAAACCAACGGCGGCAATTTGAGGCAGGCCGCCCAGATGCTAGGGCTGTCGCGCACTACGCTGTACAACAAAATC
AATAAGTGGCAGATCGATTTGACGCTTTTGCGCCCCTGA

Upstream 100 bases:

>100_bases
GAGGCGTTGCACAGATAGCCATAACAAAGTGACAACTAAGTTGACATGTAAATTTCACATGTCAATAAAATGGACATTAC
ATTCCAAAATGGAGTTGCCG

Downstream 100 bases:

>100_bases
TTGCTCTGGAGATAGGCCGTTTTATTATCAAAACACTCAGCGTTCAGGGCTGGAAATTTCTCCACTTTTTTTCCTCATTT
TGCATCCGGTGATTCAAATG

Product: PAS modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 651

Protein sequence:

>652_residues
MPTAADLLPIKDESDPIFSLPEGPEAGEWDSLFWQGWQAFNEGSQPGWIRKSILQSWRRSREYGIDPDEFVYHAPPAEQL
QAILLHNTGLISVARSIMENLLAYNPDGHINLTDAHGVTLHYCGADMTPVGSILREEVQGTNCTARCLLEQRLVYVLSGE
NWKMGLRQRHRQCAAAPVRNAEGVMIGVLTLTATPDNFNAHTLGTVQAAAEAVGQQLKLQQLLAEQQSILETLNEGVMVC
DRQGRLKTVNRYARQIFDGLEPGNKSIDELLRPQSGSLLAMPFCNDREMVFMPAGKPALSCVISLMPAPDDGRVLSVREN
QRIRAITRRVMGVSASYTFEMIYGHSSRMREAIMQARTCSRSDSTVLLTGESGTGKELFAQAIHNAGGRCNEPFVAVNCG
ALPRDLVQSELFGYVDGAFTGSRRGGAAGKFELADGGTLLLDEIGEMPLEAQTSLLRVLQESEVLRIGAAQPVKVNVRII
AATHCDLVQAVETGAFRRDLYYRLNVLSIPVPPLRERRDDIAGLVNGFIHKLSARMKKVPPQVSPTAMACLNAWHWPGNV
RELENLVERMVNLCEGLLIDLGDLPEDIRRIAPEPAPLPSSRLEDHERIHIIQVIETNGGNLRQAAQMLGLSRTTLYNKI
NKWQIDLTLLRP

Sequences:

>Translated_652_residues
MPTAADLLPIKDESDPIFSLPEGPEAGEWDSLFWQGWQAFNEGSQPGWIRKSILQSWRRSREYGIDPDEFVYHAPPAEQL
QAILLHNTGLISVARSIMENLLAYNPDGHINLTDAHGVTLHYCGADMTPVGSILREEVQGTNCTARCLLEQRLVYVLSGE
NWKMGLRQRHRQCAAAPVRNAEGVMIGVLTLTATPDNFNAHTLGTVQAAAEAVGQQLKLQQLLAEQQSILETLNEGVMVC
DRQGRLKTVNRYARQIFDGLEPGNKSIDELLRPQSGSLLAMPFCNDREMVFMPAGKPALSCVISLMPAPDDGRVLSVREN
QRIRAITRRVMGVSASYTFEMIYGHSSRMREAIMQARTCSRSDSTVLLTGESGTGKELFAQAIHNAGGRCNEPFVAVNCG
ALPRDLVQSELFGYVDGAFTGSRRGGAAGKFELADGGTLLLDEIGEMPLEAQTSLLRVLQESEVLRIGAAQPVKVNVRII
AATHCDLVQAVETGAFRRDLYYRLNVLSIPVPPLRERRDDIAGLVNGFIHKLSARMKKVPPQVSPTAMACLNAWHWPGNV
RELENLVERMVNLCEGLLIDLGDLPEDIRRIAPEPAPLPSSRLEDHERIHIIQVIETNGGNLRQAAQMLGLSRTTLYNKI
NKWQIDLTLLRP
>Mature_651_residues
PTAADLLPIKDESDPIFSLPEGPEAGEWDSLFWQGWQAFNEGSQPGWIRKSILQSWRRSREYGIDPDEFVYHAPPAEQLQ
AILLHNTGLISVARSIMENLLAYNPDGHINLTDAHGVTLHYCGADMTPVGSILREEVQGTNCTARCLLEQRLVYVLSGEN
WKMGLRQRHRQCAAAPVRNAEGVMIGVLTLTATPDNFNAHTLGTVQAAAEAVGQQLKLQQLLAEQQSILETLNEGVMVCD
RQGRLKTVNRYARQIFDGLEPGNKSIDELLRPQSGSLLAMPFCNDREMVFMPAGKPALSCVISLMPAPDDGRVLSVRENQ
RIRAITRRVMGVSASYTFEMIYGHSSRMREAIMQARTCSRSDSTVLLTGESGTGKELFAQAIHNAGGRCNEPFVAVNCGA
LPRDLVQSELFGYVDGAFTGSRRGGAAGKFELADGGTLLLDEIGEMPLEAQTSLLRVLQESEVLRIGAAQPVKVNVRIIA
ATHCDLVQAVETGAFRRDLYYRLNVLSIPVPPLRERRDDIAGLVNGFIHKLSARMKKVPPQVSPTAMACLNAWHWPGNVR
ELENLVERMVNLCEGLLIDLGDLPEDIRRIAPEPAPLPSSRLEDHERIHIIQVIETNGGNLRQAAQMLGLSRTTLYNKIN
KWQIDLTLLRP

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=324, Percent_Identity=45.3703703703704, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI1789087, Length=333, Percent_Identity=44.4444444444444, Blast_Score=251, Evalue=8e-68,
Organism=Escherichia coli, GI1790437, Length=315, Percent_Identity=45.7142857142857, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1789233, Length=499, Percent_Identity=32.8657314629259, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1786524, Length=326, Percent_Identity=45.0920245398773, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI87082117, Length=324, Percent_Identity=45.0617283950617, Blast_Score=249, Evalue=4e-67,
Organism=Escherichia coli, GI1788905, Length=309, Percent_Identity=43.3656957928803, Blast_Score=242, Evalue=5e-65,
Organism=Escherichia coli, GI1790299, Length=327, Percent_Identity=39.7553516819572, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI87082152, Length=233, Percent_Identity=45.9227467811159, Blast_Score=196, Evalue=6e-51,
Organism=Escherichia coli, GI1787583, Length=339, Percent_Identity=35.3982300884956, Blast_Score=195, Evalue=8e-51,
Organism=Escherichia coli, GI87081858, Length=528, Percent_Identity=30.4924242424242, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI87081872, Length=320, Percent_Identity=37.1875, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1789828, Length=262, Percent_Identity=35.1145038167939, Blast_Score=129, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 72067; Mature: 71935

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTAADLLPIKDESDPIFSLPEGPEAGEWDSLFWQGWQAFNEGSQPGWIRKSILQSWRRS
CCCCCCCEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
REYGIDPDEFVYHAPPAEQLQAILLHNTGLISVARSIMENLLAYNPDGHINLTDAHGVTL
CCCCCCHHHEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEE
HYCGADMTPVGSILREEVQGTNCTARCLLEQRLVYVLSGENWKMGLRQRHRQCAAAPVRN
EECCCCCCHHHHHHHHHHCCCCHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHCCCCC
AEGVMIGVLTLTATPDNFNAHTLGTVQAAAEAVGQQLKLQQLLAEQQSILETLNEGVMVC
CCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
DRQGRLKTVNRYARQIFDGLEPGNKSIDELLRPQSGSLLAMPFCNDREMVFMPAGKPALS
CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEECCCCCCEEEEECCCHHHH
CVISLMPAPDDGRVLSVRENQRIRAITRRVMGVSASYTFEMIYGHSSRMREAIMQARTCS
HHHHHCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHCC
RSDSTVLLTGESGTGKELFAQAIHNAGGRCNEPFVAVNCGALPRDLVQSELFGYVDGAFT
CCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCC
GSRRGGAAGKFELADGGTLLLDEIGEMPLEAQTSLLRVLQESEVLRIGAAQPVKVNVRII
CCCCCCCCCEEEECCCCEEHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCEEEEEEEE
AATHCDLVQAVETGAFRRDLYYRLNVLSIPVPPLRERRDDIAGLVNGFIHKLSARMKKVP
EECHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQVSPTAMACLNAWHWPGNVRELENLVERMVNLCEGLLIDLGDLPEDIRRIAPEPAPLPS
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCH
SRLEDHERIHIIQVIETNGGNLRQAAQMLGLSRTTLYNKINKWQIDLTLLRP
HHCCCCCCEEEEEEEECCCCCHHHHHHHHCCHHHHHHHCCCEEEEEEEEECC
>Mature Secondary Structure 
PTAADLLPIKDESDPIFSLPEGPEAGEWDSLFWQGWQAFNEGSQPGWIRKSILQSWRRS
CCCCCCEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
REYGIDPDEFVYHAPPAEQLQAILLHNTGLISVARSIMENLLAYNPDGHINLTDAHGVTL
CCCCCCHHHEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEE
HYCGADMTPVGSILREEVQGTNCTARCLLEQRLVYVLSGENWKMGLRQRHRQCAAAPVRN
EECCCCCCHHHHHHHHHHCCCCHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHCCCCC
AEGVMIGVLTLTATPDNFNAHTLGTVQAAAEAVGQQLKLQQLLAEQQSILETLNEGVMVC
CCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
DRQGRLKTVNRYARQIFDGLEPGNKSIDELLRPQSGSLLAMPFCNDREMVFMPAGKPALS
CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEECCCCCCEEEEECCCHHHH
CVISLMPAPDDGRVLSVRENQRIRAITRRVMGVSASYTFEMIYGHSSRMREAIMQARTCS
HHHHHCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHCC
RSDSTVLLTGESGTGKELFAQAIHNAGGRCNEPFVAVNCGALPRDLVQSELFGYVDGAFT
CCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCC
GSRRGGAAGKFELADGGTLLLDEIGEMPLEAQTSLLRVLQESEVLRIGAAQPVKVNVRII
CCCCCCCCCEEEECCCCEEHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCEEEEEEEE
AATHCDLVQAVETGAFRRDLYYRLNVLSIPVPPLRERRDDIAGLVNGFIHKLSARMKKVP
EECHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQVSPTAMACLNAWHWPGNVRELENLVERMVNLCEGLLIDLGDLPEDIRRIAPEPAPLPS
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCH
SRLEDHERIHIIQVIETNGGNLRQAAQMLGLSRTTLYNKINKWQIDLTLLRP
HHCCCCCCEEEEEEEECCCCCHHHHHHHHCCHHHHHHHCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA