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The map label for this gene is arsR [H]

Identifier: 157370631

GI number: 157370631

Start: 2612372

End: 2612692

Strand: Reverse

Name: arsR [H]

Synonym: Spro_2391

Alternate gene names: 157370631

Gene position: 2612692-2612372 (Counterclockwise)

Preceding gene: 157370632

Following gene: 157370630

Centisome position: 47.95

GC content: 53.27

Gene sequence:

>321_bases
ATGCTACAACCCGTTCAGCTTTTCAAAATTTTGTCGGATGAAACTCGACTGGCCATCATTATGCTTCTCAGAGAGTCGGG
GGAGTTATGCGTTTGTGATATCTGCGGGGCCACTTCGGAGTCACAGCCTAAAATATCCCGCCACATGGCGATACTACGCA
ATGCAGGGCTGGTCATTGATCGTCGTGAGGGGAAATGGATCCACTATCGACTCTCGCCGCATATCCCTGCCTGGGCGGCA
GAGACCATCACGGCATCCTGGCAGTGCCTGCGTGAAGATGTTCGCGGATGGCTGGCACAATCAGCGACATCCTCCTGTTA
A

Upstream 100 bases:

>100_bases
GGAAATTTCTCCACTTTTTTTCCTCATTTTGCATCCGGTGATTCAAATGCCAACACATATGAATTATCATATGTGTAATT
TAAGCGCATTGAGGTTCAAA

Downstream 100 bases:

>100_bases
GCCCTAGGAAACACATTGCTTTAATCATATATAACGGAGTCTGATATGTTACTGGCAGGGAGTCTCTTTTTACTGACGCT
GATTCTGGTCATCTGGCAGC

Product: DNA-binding transcriptional repressor ArsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MLQPVQLFKILSDETRLAIIMLLRESGELCVCDICGATSESQPKISRHMAILRNAGLVIDRREGKWIHYRLSPHIPAWAA
ETITASWQCLREDVRGWLAQSATSSC

Sequences:

>Translated_106_residues
MLQPVQLFKILSDETRLAIIMLLRESGELCVCDICGATSESQPKISRHMAILRNAGLVIDRREGKWIHYRLSPHIPAWAA
ETITASWQCLREDVRGWLAQSATSSC
>Mature_106_residues
MLQPVQLFKILSDETRLAIIMLLRESGELCVCDICGATSESQPKISRHMAILRNAGLVIDRREGKWIHYRLSPHIPAWAA
ETITASWQCLREDVRGWLAQSATSSC

Specific function: Transcriptional repressor for the arsEFG operon. ArsE is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsE is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=106, Percent_Identity=60.377358490566, Blast_Score=146, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11950; Mature: 11950

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQPVQLFKILSDETRLAIIMLLRESGELCVCDICGATSESQPKISRHMAILRNAGLVID
CCCHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEE
RREGKWIHYRLSPHIPAWAAETITASWQCLREDVRGWLAQSATSSC
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLQPVQLFKILSDETRLAIIMLLRESGELCVCDICGATSESQPKISRHMAILRNAGLVID
CCCHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEE
RREGKWIHYRLSPHIPAWAAETITASWQCLREDVRGWLAQSATSSC
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721697; 8041620; 9278503 [H]