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The map label for this gene is arsC [H]

Identifier: 157370629

GI number: 157370629

Start: 2610593

End: 2611024

Strand: Reverse

Name: arsC [H]

Synonym: Spro_2389

Alternate gene names: 157370629

Gene position: 2611024-2610593 (Counterclockwise)

Preceding gene: 157370630

Following gene: 157370628

Centisome position: 47.92

GC content: 50.0

Gene sequence:

>432_bases
ATGAGCAACATTGTCATCTATCACAACCCGGCCTGTGGCACCTCACGTAACACGCTGGAGATGATCCGCAACAGCGGTAA
CGAACCGACGATCATTTATTATCTCGACACACCACCATCGCATGATGAACTGGTTCACCTTATTGCGGATATGGGAATTA
GCGTCCGTGCGTTGCTGCGCAAAAACGTTGAACCCTATGAGCAGCTTGGCCTGGATAATGGAGTATTGACTGACGAGCAG
CTGATTGAATTTATGCTTCAGTATCCGATCCTGATCAACCGCCCCATCGTCGTCACCCCCATGGGAACCCGATTGTGTCG
TCCTTCCGAAGTGGTGTTGGAGATCCTTCCAGATCCGCAACAAACCGCATTCACCAATGAAGACGGTGAAAAGGTGACAA
ACCAGGCAGGCAATAGAATCAAGCCAGATTGA

Upstream 100 bases:

>100_bases
TTACTTCCGTACCGGCATCGTCATGACCCTGCCCGTTCTGTTTGTCACTCTGGCCGCCCTGGCGTTGCGGCTCTCCGTTA
CTTTCTAATGAGATACTGAT

Downstream 100 bases:

>100_bases
CATCCTCCCCGTCCTAAATGAACTGCCCCCCAAAAGGACGGGGTTTTACGGCACGCTGGATAATAAAGGGGTTAAAAGTT
AAGGCATAACCGCCTGCGGC

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MSNIVIYHNPACGTSRNTLEMIRNSGNEPTIIYYLDTPPSHDELVHLIADMGISVRALLRKNVEPYEQLGLDNGVLTDEQ
LIEFMLQYPILINRPIVVTPMGTRLCRPSEVVLEILPDPQQTAFTNEDGEKVTNQAGNRIKPD

Sequences:

>Translated_143_residues
MSNIVIYHNPACGTSRNTLEMIRNSGNEPTIIYYLDTPPSHDELVHLIADMGISVRALLRKNVEPYEQLGLDNGVLTDEQ
LIEFMLQYPILINRPIVVTPMGTRLCRPSEVVLEILPDPQQTAFTNEDGEKVTNQAGNRIKPD
>Mature_142_residues
SNIVIYHNPACGTSRNTLEMIRNSGNEPTIIYYLDTPPSHDELVHLIADMGISVRALLRKNVEPYEQLGLDNGVLTDEQL
IEFMLQYPILINRPIVVTPMGTRLCRPSEVVLEILPDPQQTAFTNEDGEKVTNQAGNRIKPD

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=141, Percent_Identity=80.1418439716312, Blast_Score=238, Evalue=1e-64,
Organism=Escherichia coli, GI1788841, Length=116, Percent_Identity=40.5172413793103, Blast_Score=91, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 16072; Mature: 15940

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIVIYHNPACGTSRNTLEMIRNSGNEPTIIYYLDTPPSHDELVHLIADMGISVRALLR
CCCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHH
KNVEPYEQLGLDNGVLTDEQLIEFMLQYPILINRPIVVTPMGTRLCRPSEVVLEILPDPQ
CCCCHHHHCCCCCCCCCHHHHHHHHHHCCCEECCCEEEEECCCCCCCHHHHHHEECCCCC
QTAFTNEDGEKVTNQAGNRIKPD
HHCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SNIVIYHNPACGTSRNTLEMIRNSGNEPTIIYYLDTPPSHDELVHLIADMGISVRALLR
CCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHH
KNVEPYEQLGLDNGVLTDEQLIEFMLQYPILINRPIVVTPMGTRLCRPSEVVLEILPDPQ
CCCCHHHHCCCCCCCCCHHHHHHHHHHCCCEECCCEEEEECCCCCCCHHHHHHEECCCCC
QTAFTNEDGEKVTNQAGNRIKPD
HHCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006011 [H]