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The map label for this gene is fabZ [H]

Identifier: 157370625

GI number: 157370625

Start: 2605560

End: 2606015

Strand: Reverse

Name: fabZ [H]

Synonym: Spro_2385

Alternate gene names: 157370625

Gene position: 2606015-2605560 (Counterclockwise)

Preceding gene: 157370626

Following gene: 157370624

Centisome position: 47.83

GC content: 56.8

Gene sequence:

>456_bases
ATGCCGCTCAATGGTAAACCACTACAGTTTCAGGATGTTCAATCTATCCTGCCGCACCGCTTCCCCTGTCTGCTGGTTGA
CCGCATTCTGCCTGACGGCACCTCCGTTGCCGAAGGCCGCTTAAGTGCCATCAAAAATATCACTGCCAACGAACCGACCT
TCTGGACTGGCCACCACCAGACCACGGTGTTTCCCGGCATATTAATGGTGGAGGCACTGGCACAAACCACCGGCTTGTTG
GCGCATTACTTTCTCAGCCCGCTATTACCCGGCGAACATTACTATTTTGCCGCCATTCATCACGCTCGCTTCTATCGCTC
GGCCCGGCCCGGCGATCAGCTTCGCATGGATGTCGCCTTTGTCCGACAGCGCTCCGGCCTTGCCCGCTTTACCGGTCGTG
CTACGGTAAATGGCCGCCGCATCTGTACCGCCGAGTTTATGTGCGCTCGTAAGTAG

Upstream 100 bases:

>100_bases
TGCATCCAATGATAATAACATTATAATGTTATTACACTTCGACAGGCACAGATGCCGGCACAAGCTGAGCTTTGTCCCGC
TGACAGGACCCTAATCAATC

Downstream 100 bases:

>100_bases
AACCGCCGTTTTTGATGGAGGCTTAAAGAAATAACTATGTCTATGGTTGATAAATTGCTCAATAGCCTGGATTTTTCTCC
TCGCGGTCAGGTGATTGCTC

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MPLNGKPLQFQDVQSILPHRFPCLLVDRILPDGTSVAEGRLSAIKNITANEPTFWTGHHQTTVFPGILMVEALAQTTGLL
AHYFLSPLLPGEHYYFAAIHHARFYRSARPGDQLRMDVAFVRQRSGLARFTGRATVNGRRICTAEFMCARK

Sequences:

>Translated_151_residues
MPLNGKPLQFQDVQSILPHRFPCLLVDRILPDGTSVAEGRLSAIKNITANEPTFWTGHHQTTVFPGILMVEALAQTTGLL
AHYFLSPLLPGEHYYFAAIHHARFYRSARPGDQLRMDVAFVRQRSGLARFTGRATVNGRRICTAEFMCARK
>Mature_150_residues
PLNGKPLQFQDVQSILPHRFPCLLVDRILPDGTSVAEGRLSAIKNITANEPTFWTGHHQTTVFPGILMVEALAQTTGLLA
HYFLSPLLPGEHYYFAAIHHARFYRSARPGDQLRMDVAFVRQRSGLARFTGRATVNGRRICTAEFMCARK

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=152, Percent_Identity=50, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16964; Mature: 16833

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNGKPLQFQDVQSILPHRFPCLLVDRILPDGTSVAEGRLSAIKNITANEPTFWTGHHQ
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEECCCCC
TTVFPGILMVEALAQTTGLLAHYFLSPLLPGEHYYFAAIHHARFYRSARPGDQLRMDVAF
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHH
VRQRSGLARFTGRATVNGRRICTAEFMCARK
HHHHCCCHHHCCCEECCCCEEEHHHHHCCCC
>Mature Secondary Structure 
PLNGKPLQFQDVQSILPHRFPCLLVDRILPDGTSVAEGRLSAIKNITANEPTFWTGHHQ
CCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEECCCCC
TTVFPGILMVEALAQTTGLLAHYFLSPLLPGEHYYFAAIHHARFYRSARPGDQLRMDVAF
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHH
VRQRSGLARFTGRATVNGRRICTAEFMCARK
HHHHCCCHHHCCCEECCCCEEEHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA