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The map label for this gene is alsR [H]

Identifier: 157370566

GI number: 157370566

Start: 2540322

End: 2541242

Strand: Reverse

Name: alsR [H]

Synonym: Spro_2326

Alternate gene names: 157370566

Gene position: 2541242-2540322 (Counterclockwise)

Preceding gene: 157370569

Following gene: 157370562

Centisome position: 46.64

GC content: 62.65

Gene sequence:

>921_bases
ATGTCTATGATTGAACTCCGTCGCCTGCGGGCGTTCGTTACCGTGGTGGAAGAAGGCAATATCACCCGCGCCGCCGAACG
ACTGTTTATTCAGCAGCCGCCGTTAACCCGCCTGTTGCAAGGGCTGGAAGATGAGCTGGGGGTAAAACTGTTGCAGCGTC
TGCCACGCGGCGTGCGCGTCACCGAAGCCGGCAATGTGCTGTTCAATGAAGCTCGTGCCCTGTTGGCACGGGCAGAGCAA
CTGACCGAGGCGGTGCACCGTGCCGCACGGGGTGAACAAGGGCATATCGCCATCGGCTTCACCAGTTCGGCCGCTCTGCA
CCCGTTTGTGCCCAATTTGCTGCGCCGTTACCGGGAGATCCTGCCGGGCATTACCACCCAGTTGGAAGAGGCCGGCAGCG
GTGAACTATTGGAGGCACTGGTGGATGAACGCCTTGACGTGGCCTTTGTGCGCTCGCCGGTGGGCGGCATTCCAGGGTTG
ACGATTGAACCGGTGCTGCGCGAACCTATGCTGGTCGCCCTGCCGGTCGGCCACCCGCTGGCCGTCAACAGTGAGCAACC
CTTGCCGCTGGAGGCATTAACCCAAGAAGCCTTTATTCTTTATCGTCGGCCTGCGGGTCAGGGTTTGTACGACGCCATTC
TGGCGGCCTGCCACCGCGCCGGGTTCAGCCCGCGAGTGATTCAGGAGGCCCCGCGCCTGCCCGCGACCCTCAGTTTGGTC
GGTGCCGGTTTGGGGCTTTCCATCGTGCCTGCCTCGATGCGACGTTTGGGGGGCGACGGCATTGTCTACCGGGCGATTGG
CGATCGGGCCCAGCTCAGTGCGCCGCTTTATCTGGCGCTGCGCAACAACCGAACATCGGCCATCATCACGCGTTTTCGCG
ATTTGGTGACCGAAGCGGTCAGCGAGCAGCCACCCGGCTAA

Upstream 100 bases:

>100_bases
TTGCCGCTTCCAGATTGCTTTTTATGATGGCTGGTATGATGCGCGCCGCCATGTCATGCTGTCTAATGCATTTCATAAGC
AACAAGGATACCTTCAAGGT

Downstream 100 bases:

>100_bases
TCTTCCTTGTCGGCGATGCGCGTCAGGTGGATCACCAGATACAGCAGCTCATCGTTCGACATTTCCATCTGCAGCAGATT
TTTCACGTAGTCGCGGATCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSMIELRRLRAFVTVVEEGNITRAAERLFIQQPPLTRLLQGLEDELGVKLLQRLPRGVRVTEAGNVLFNEARALLARAEQ
LTEAVHRAARGEQGHIAIGFTSSAALHPFVPNLLRRYREILPGITTQLEEAGSGELLEALVDERLDVAFVRSPVGGIPGL
TIEPVLREPMLVALPVGHPLAVNSEQPLPLEALTQEAFILYRRPAGQGLYDAILAACHRAGFSPRVIQEAPRLPATLSLV
GAGLGLSIVPASMRRLGGDGIVYRAIGDRAQLSAPLYLALRNNRTSAIITRFRDLVTEAVSEQPPG

Sequences:

>Translated_306_residues
MSMIELRRLRAFVTVVEEGNITRAAERLFIQQPPLTRLLQGLEDELGVKLLQRLPRGVRVTEAGNVLFNEARALLARAEQ
LTEAVHRAARGEQGHIAIGFTSSAALHPFVPNLLRRYREILPGITTQLEEAGSGELLEALVDERLDVAFVRSPVGGIPGL
TIEPVLREPMLVALPVGHPLAVNSEQPLPLEALTQEAFILYRRPAGQGLYDAILAACHRAGFSPRVIQEAPRLPATLSLV
GAGLGLSIVPASMRRLGGDGIVYRAIGDRAQLSAPLYLALRNNRTSAIITRFRDLVTEAVSEQPPG
>Mature_305_residues
SMIELRRLRAFVTVVEEGNITRAAERLFIQQPPLTRLLQGLEDELGVKLLQRLPRGVRVTEAGNVLFNEARALLARAEQL
TEAVHRAARGEQGHIAIGFTSSAALHPFVPNLLRRYREILPGITTQLEEAGSGELLEALVDERLDVAFVRSPVGGIPGLT
IEPVLREPMLVALPVGHPLAVNSEQPLPLEALTQEAFILYRRPAGQGLYDAILAACHRAGFSPRVIQEAPRLPATLSLVG
AGLGLSIVPASMRRLGGDGIVYRAIGDRAQLSAPLYLALRNNRTSAIITRFRDLVTEAVSEQPPG

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=291, Percent_Identity=34.020618556701, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI2367136, Length=294, Percent_Identity=29.5918367346939, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788887, Length=309, Percent_Identity=32.3624595469256, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1788297, Length=258, Percent_Identity=31.3953488372093, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI157672245, Length=250, Percent_Identity=31.2, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1790399, Length=265, Percent_Identity=28.6792452830189, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI145693105, Length=246, Percent_Identity=27.6422764227642, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788748, Length=248, Percent_Identity=29.8387096774194, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789173, Length=184, Percent_Identity=33.695652173913, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788481, Length=203, Percent_Identity=30.5418719211823, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787806, Length=253, Percent_Identity=28.4584980237154, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787530, Length=253, Percent_Identity=24.901185770751, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789506, Length=249, Percent_Identity=24.8995983935743, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788296, Length=237, Percent_Identity=26.5822784810127, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=300, Percent_Identity=24.3333333333333, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082184, Length=296, Percent_Identity=23.3108108108108, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789204, Length=286, Percent_Identity=26.2237762237762, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789639, Length=129, Percent_Identity=31.7829457364341, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786401, Length=140, Percent_Identity=31.4285714285714, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33232; Mature: 33101

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMIELRRLRAFVTVVEEGNITRAAERLFIQQPPLTRLLQGLEDELGVKLLQRLPRGVRV
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
TEAGNVLFNEARALLARAEQLTEAVHRAARGEQGHIAIGFTSSAALHPFVPNLLRRYREI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LPGITTQLEEAGSGELLEALVDERLDVAFVRSPVGGIPGLTIEPVLREPMLVALPVGHPL
HCCHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCEECHHHCCCEEEEEECCCCE
AVNSEQPLPLEALTQEAFILYRRPAGQGLYDAILAACHRAGFSPRVIQEAPRLPATLSLV
EECCCCCCCHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHH
GAGLGLSIVPASMRRLGGDGIVYRAIGDRAQLSAPLYLALRNNRTSAIITRFRDLVTEAV
HCCCCHHHHHHHHHHCCCCCEEEEECCCCHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
SEQPPG
HCCCCC
>Mature Secondary Structure 
SMIELRRLRAFVTVVEEGNITRAAERLFIQQPPLTRLLQGLEDELGVKLLQRLPRGVRV
CHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
TEAGNVLFNEARALLARAEQLTEAVHRAARGEQGHIAIGFTSSAALHPFVPNLLRRYREI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LPGITTQLEEAGSGELLEALVDERLDVAFVRSPVGGIPGLTIEPVLREPMLVALPVGHPL
HCCHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCEECHHHCCCEEEEEECCCCE
AVNSEQPLPLEALTQEAFILYRRPAGQGLYDAILAACHRAGFSPRVIQEAPRLPATLSLV
EECCCCCCCHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHH
GAGLGLSIVPASMRRLGGDGIVYRAIGDRAQLSAPLYLALRNNRTSAIITRFRDLVTEAV
HCCCCHHHHHHHHHHCCCCCEEEEECCCCHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
SEQPPG
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]