Click here to switch to the map view.

The map label for this gene is inh [H]

Identifier: 157370569

GI number: 157370569

Start: 2542473

End: 2542889

Strand: Reverse

Name: inh [H]

Synonym: Spro_2329

Alternate gene names: 157370569

Gene position: 2542889-2542473 (Counterclockwise)

Preceding gene: 157370571

Following gene: 157370566

Centisome position: 46.67

GC content: 59.95

Gene sequence:

>417_bases
ATGCCGAGATTTCTCTCTATACGCGCAGTACGGCGCGTTGCCCTGACAGGAGTTGTTATGAGCATGATGTTAAGCAGCAC
TACCTTTGCCAGTTCACTGCCCCTGCTGGCCCCCTCTGCGCTGAAAGGGCACTGGCAGTTGAACGATGCCGAAGGCAAAG
CCGCCGCCTGCGAAGTTGAGTTAAGCGATGAATTGATCGAAGGCACCAACGCCTACCGTTTTACCGCCTCTGCGCAATGT
CTGCAGCCGCTGGCCCTCGCCGAACTGCCGGTCGCCTGGCGCCCAACGCCGGACGGCATGACGCTGACCAACGCCGACGG
CAGCATGGTCGCGTTCCTGGCGCTGACGGCCCCCAAACGCTACGAAGTGATAAATCATCACGGCAAGCCGCGCTTTACGC
TGACGCCACGCCAATAA

Upstream 100 bases:

>100_bases
CCGCAAATTGCAATAATGAGCCTGCAATCAAATTACCCTTCACTCACCCGGAAACTGGGATCGTGCTATGGTATTAACGG
ATTTAAGTAAGGAGTGGCCG

Downstream 100 bases:

>100_bases
CCGTCTTTTCTGGCGTGACGGCAGCGTAAAAAACCTGTCGTCACGCCACCAACAATCCCATTAACGCACCGCCCGCCAAA
ACCCACAGCGGATGAATACG

Product: metalloprotease inhibitor I38

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MPRFLSIRAVRRVALTGVVMSMMLSSTTFASSLPLLAPSALKGHWQLNDAEGKAAACEVELSDELIEGTNAYRFTASAQC
LQPLALAELPVAWRPTPDGMTLTNADGSMVAFLALTAPKRYEVINHHGKPRFTLTPRQ

Sequences:

>Translated_138_residues
MPRFLSIRAVRRVALTGVVMSMMLSSTTFASSLPLLAPSALKGHWQLNDAEGKAAACEVELSDELIEGTNAYRFTASAQC
LQPLALAELPVAWRPTPDGMTLTNADGSMVAFLALTAPKRYEVINHHGKPRFTLTPRQ
>Mature_137_residues
PRFLSIRAVRRVALTGVVMSMMLSSTTFASSLPLLAPSALKGHWQLNDAEGKAAACEVELSDELIEGTNAYRFTASAQCL
QPLALAELPVAWRPTPDGMTLTNADGSMVAFLALTAPKRYEVINHHGKPRFTLTPRQ

Specific function: Inhibitor of the extracellular proteases A, B, and C of E.chrysanthemi and the S.marcescens 50 kDa extracellular protease. It forms a non-covalent bond with the proteases and may prevent autocatalytic cleavage of the proteases zymogen in the periplasm [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I38 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003086
- InterPro:   IPR021140
- InterPro:   IPR022815
- InterPro:   IPR016085
- ProDom:   PD015804 [H]

Pfam domain/function: PF02974 Inh [H]

EC number: NA

Molecular weight: Translated: 14983; Mature: 14851

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFLSIRAVRRVALTGVVMSMMLSSTTFASSLPLLAPSALKGHWQLNDAEGKAAACEVE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEEEE
LSDELIEGTNAYRFTASAQCLQPLALAELPVAWRPTPDGMTLTNADGSMVAFLALTAPKR
CCHHHHCCCCCEEEECCHHHHCHHHHHHCCCEECCCCCCCEEECCCCCEEEEEEECCCCH
YEVINHHGKPRFTLTPRQ
HHHHCCCCCCCEEECCCC
>Mature Secondary Structure 
PRFLSIRAVRRVALTGVVMSMMLSSTTFASSLPLLAPSALKGHWQLNDAEGKAAACEVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEEEE
LSDELIEGTNAYRFTASAQCLQPLALAELPVAWRPTPDGMTLTNADGSMVAFLALTAPKR
CCHHHHCCCCCEEEECCHHHHCHHHHHHCCCEECCCCCCCEEECCCCCEEEEEEECCCCH
YEVINHHGKPRFTLTPRQ
HHHHCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2654540; 2184029; 7752231 [H]