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The map label for this gene is xylR [H]

Identifier: 157370538

GI number: 157370538

Start: 2501268

End: 2502443

Strand: Direct

Name: xylR [H]

Synonym: Spro_2298

Alternate gene names: 157370538

Gene position: 2501268-2502443 (Clockwise)

Preceding gene: 157370529

Following gene: 157370539

Centisome position: 45.9

GC content: 57.31

Gene sequence:

>1176_bases
ATGACGACTTCCGGCACTAACCTTGAACATGCTCGTGCACACAACCGGCGCGTAGTGATAGAGGCTATCCGTCTGCACGG
TGAACTGACCCGTGCCGAAATTGCCCGGCTGACCTCACTGACGCCGCAAACCGTTTCAAACATTGCAACAGAACTGGAAC
AGGCCGGTATTCTCTCATCGCACCTGCCGCGTCGTGCCGGCGGGCGAGGTCAACCGGCCACGCCGTTGACCCTGAATCCA
GATAGCGCGTATTCCATCGGTATCCATCTGGATCACCAGTCACTGCTGATCATCGTGGTTGATCTCTCAGGCAGCGTTCG
TTTCCACCGGCTGATTATGGTGCAAAAGCCGCAACCTGCTGCCACCTTGAAACTGATTTGTGATGTACTGCAAGAAATGC
GCCAGCAGCCGGATCTGAGCTGGAGAAAAATGCTGGGCATCGGCGTAGTGATGCCGGGGCCGTTTGGCGTGGAAGGGATC
TCGTCGGTCGGGCCGACCACGCTTAACGGTTGGGAAAATATCGATGTGGTGGCTGAACTTAACGCGCAAAGTGGCCTGCC
GGTGACGCTGGAGAACGATGCTACCGTGGCCGCTATCGGCGAGCGTTTGCACGGTGTCGCCAGGCAGCTTAATTCCTTTA
TTTATTTGTATCTCGGGACCGGACTTGGGGCAGGGATTTTTACCGATGGCCGAATTTATACCGGCCATGCGCACAATGCT
GGTGAAGTCGGCCACATGATTGTGCAACCGGGTGGGCGGGCCTGCTACTGTGGCAACCAGGGGTGTCTGGAGCGTTATGT
CTCGTTGCAGGCGGCTTATGAGAGCTGCGGGCTGGATCCGATGCGCGCCATGCCGCAAGACCTGCTGACGCTACCGCAGC
CGCAGATCGACGCCTGGCTGGATACGGCGGTGCCGGCGTTACGCCAGGCGATCAATATCATTGAGTGTATGTTTGACGCC
GAAGCGGTGATTATTGGCGGGCTGATGCCGGAAAGTATCGTAGAACAGTTGATCAAGCGCCTGGCGCCACTGCACCGGTC
GGTGCGCAGCAAATATCTCGACGGCCTGCGGGTTCGATTGGGGACTACCGGCGCGGATACCGCCGCATTAGGTGCGGCCG
CGTTACCGCTGTTTGATGAATTTAACCCGCGCTATGAAGTTTTATTGAAGTCATAA

Upstream 100 bases:

>100_bases
TGTGCGTTCTCCGGTGTTAAAAAGATTCTTAAATCAATTTGATTGCTTTATTGGAGGGCACCATACTGCAAAGACGATTT
CCCTTTCTGCATAGGCAGTT

Downstream 100 bases:

>100_bases
ATTTCATTCCCCCGATTTGTATTCTTGCCCGTTATTGGTGCAGGCTCACCATTAACTCAATATAAGCAAACGGTTGCTAT
TTAAAGGCAACCGTTTGCTT

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTTSGTNLEHARAHNRRVVIEAIRLHGELTRAEIARLTSLTPQTVSNIATELEQAGILSSHLPRRAGGRGQPATPLTLNP
DSAYSIGIHLDHQSLLIIVVDLSGSVRFHRLIMVQKPQPAATLKLICDVLQEMRQQPDLSWRKMLGIGVVMPGPFGVEGI
SSVGPTTLNGWENIDVVAELNAQSGLPVTLENDATVAAIGERLHGVARQLNSFIYLYLGTGLGAGIFTDGRIYTGHAHNA
GEVGHMIVQPGGRACYCGNQGCLERYVSLQAAYESCGLDPMRAMPQDLLTLPQPQIDAWLDTAVPALRQAINIIECMFDA
EAVIIGGLMPESIVEQLIKRLAPLHRSVRSKYLDGLRVRLGTTGADTAALGAAALPLFDEFNPRYEVLLKS

Sequences:

>Translated_391_residues
MTTSGTNLEHARAHNRRVVIEAIRLHGELTRAEIARLTSLTPQTVSNIATELEQAGILSSHLPRRAGGRGQPATPLTLNP
DSAYSIGIHLDHQSLLIIVVDLSGSVRFHRLIMVQKPQPAATLKLICDVLQEMRQQPDLSWRKMLGIGVVMPGPFGVEGI
SSVGPTTLNGWENIDVVAELNAQSGLPVTLENDATVAAIGERLHGVARQLNSFIYLYLGTGLGAGIFTDGRIYTGHAHNA
GEVGHMIVQPGGRACYCGNQGCLERYVSLQAAYESCGLDPMRAMPQDLLTLPQPQIDAWLDTAVPALRQAINIIECMFDA
EAVIIGGLMPESIVEQLIKRLAPLHRSVRSKYLDGLRVRLGTTGADTAALGAAALPLFDEFNPRYEVLLKS
>Mature_390_residues
TTSGTNLEHARAHNRRVVIEAIRLHGELTRAEIARLTSLTPQTVSNIATELEQAGILSSHLPRRAGGRGQPATPLTLNPD
SAYSIGIHLDHQSLLIIVVDLSGSVRFHRLIMVQKPQPAATLKLICDVLQEMRQQPDLSWRKMLGIGVVMPGPFGVEGIS
SVGPTTLNGWENIDVVAELNAQSGLPVTLENDATVAAIGERLHGVARQLNSFIYLYLGTGLGAGIFTDGRIYTGHAHNAG
EVGHMIVQPGGRACYCGNQGCLERYVSLQAAYESCGLDPMRAMPQDLLTLPQPQIDAWLDTAVPALRQAINIIECMFDAE
AVIIGGLMPESIVEQLIKRLAPLHRSVRSKYLDGLRVRLGTTGADTAALGAAALPLFDEFNPRYEVLLKS

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=127, Percent_Identity=34.6456692913386, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4885285, Length=127, Percent_Identity=34.6456692913386, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI298566315, Length=127, Percent_Identity=34.6456692913386, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI190014632, Length=127, Percent_Identity=34.6456692913386, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787878, Length=290, Percent_Identity=25.1724137931034, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1786891, Length=393, Percent_Identity=24.6819338422392, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI87082127, Length=320, Percent_Identity=26.5625, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787363, Length=318, Percent_Identity=25.4716981132075, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790522, Length=113, Percent_Identity=35.3982300884956, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42233; Mature: 42102

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSGTNLEHARAHNRRVVIEAIRLHGELTRAEIARLTSLTPQTVSNIATELEQAGILSS
CCCCCCCCHHHHHCCCEEEEHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHH
HLPRRAGGRGQPATPLTLNPDSAYSIGIHLDHQSLLIIVVDLSGSVRFHRLIMVQKPQPA
CCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCEEEEEEEECCCCEEEEEEEEEECCCCH
ATLKLICDVLQEMRQQPDLSWRKMLGIGVVMPGPFGVEGISSVGPTTLNGWENIDVVAEL
HHHHHHHHHHHHHHHCCCCCHHHHHCCCEECCCCCCCCCHHHCCCCCCCCCCCEEEEEEE
NAQSGLPVTLENDATVAAIGERLHGVARQLNSFIYLYLGTGLGAGIFTDGRIYTGHAHNA
CCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEECCEEEECCCCCC
GEVGHMIVQPGGRACYCGNQGCLERYVSLQAAYESCGLDPMRAMPQDLLTLPQPQIDAWL
CCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHCCCCCHHHHHH
DTAVPALRQAINIIECMFDAEAVIIGGLMPESIVEQLIKRLAPLHRSVRSKYLDGLRVRL
HHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
GTTGADTAALGAAALPLFDEFNPRYEVLLKS
CCCCCCHHHHHHHHCCHHHCCCCCEEEEECC
>Mature Secondary Structure 
TTSGTNLEHARAHNRRVVIEAIRLHGELTRAEIARLTSLTPQTVSNIATELEQAGILSS
CCCCCCCHHHHHCCCEEEEHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHH
HLPRRAGGRGQPATPLTLNPDSAYSIGIHLDHQSLLIIVVDLSGSVRFHRLIMVQKPQPA
CCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCEEEEEEEECCCCEEEEEEEEEECCCCH
ATLKLICDVLQEMRQQPDLSWRKMLGIGVVMPGPFGVEGISSVGPTTLNGWENIDVVAEL
HHHHHHHHHHHHHHHCCCCCHHHHHCCCEECCCCCCCCCHHHCCCCCCCCCCCEEEEEEE
NAQSGLPVTLENDATVAAIGERLHGVARQLNSFIYLYLGTGLGAGIFTDGRIYTGHAHNA
CCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEECCEEEECCCCCC
GEVGHMIVQPGGRACYCGNQGCLERYVSLQAAYESCGLDPMRAMPQDLLTLPQPQIDAWL
CCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHCCCCCHHHHHH
DTAVPALRQAINIIECMFDAEAVIIGGLMPESIVEQLIKRLAPLHRSVRSKYLDGLRVRL
HHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
GTTGADTAALGAAALPLFDEFNPRYEVLLKS
CCCCCCHHHHHHHHCCHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]