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The map label for this gene is anmK

Identifier: 157370456

GI number: 157370456

Start: 2417279

End: 2418400

Strand: Direct

Name: anmK

Synonym: Spro_2216

Alternate gene names: 157370456

Gene position: 2417279-2418400 (Clockwise)

Preceding gene: 157370454

Following gene: 157370457

Centisome position: 44.36

GC content: 59.27

Gene sequence:

>1122_bases
ATGAAGTCAGGCCGCTATATAGGTGTTATGTCTGGCACCAGTCTGGATGGGGTCGATGTGGTGCTTGCTGCGATTGACGG
ACGTATGGTGGCGCAACAGGCCAGTTACAGCCATCCGATGCCGCTCCAACTGAAGCAGGATATTCTCGGGATGTGCCAGG
GCCAGCAGACCACGCTTTCTGCGGTTGGACGGCTGGATGCGCAGCTTGGCACGCTGTTTGGCGAGGCGGTACTGGGCTTG
CTGAAGCAAACCGGTGTGGCTGCGCACGACATTACCGCCATTGGTTGTCATGGCCAGACGGTTTGGCATGAACCCGAAGG
GGATGCGCGTTTTTCTATGCAGTTGGGCGACAATAATCGCATTGCCGCACTGACCAATATCACCACCGTTGGCGATTTTC
GCCGACGTGATATGGCCTACGGCGGTCAGGGAGCTCCGTTGGTACCGGCTTTCCATCAGGCATTGCTGTCGCACCCGGTA
GAGCGTCGCATGGTGCTGAATATCGGCGGCATAGCCAATCTGTCGATGCTGTTGCCGGGGGCCGCGGTGCGTGGCTTTGA
TACCGGGCCGGGCAATATGCTGATGGATGCCTGGATATGGCGTCATCAATCACAGCCTTACGATAAGGATGGTGGCTGGG
CGATGGCGGGGCGCGTTTGCTTGCCGCTGTTGCAACAGATGCTGGCCGATCCTTACTTCTCGCTACCGGCACCGAAAAGC
ACCGGGCGTGAATATTTCAACGCGGCCTGGCTGGAGCGTCAGCTCGCGGGTCTGGCGGCAGTCAGCCCGGTTGATGTGCA
AACCACGTTGACGGAACTGACGGCGGTCACCATTTGCGAACAGGTTCAGTTGGCGGGCGGCTGTGAACGTCTGCTGGTTT
GCGGCGGTGGGGCACGGAATATGTTGCTGATGGCACGAATGTCTGCGTTGTTGCCAGGAACCGAGGTGTGCCTGACGGAT
GATTTCGGCATTAGCGGCGACGATATGGAGGCGCTGGCCTTCGCCTGGTTGGCGTTTCGCACCTTGTCCGGGCAGCCCGG
CAATCTGCCTTCGGTGACCGGTGCCAGTTGTGAAACCCTGCTGGGTGGGATTTATCCGGTTTTGCCTTTGGGGGGCCGTT
AG

Upstream 100 bases:

>100_bases
GGTGAAAAAATACAACATATTTCATGGCGTTAATGTGGCAATTCTGGTTTATTTGTCAGGTCAAAATTTTGCTTCCCCGT
AAAGGGTAAAGGATGTCGCT

Downstream 100 bases:

>100_bases
CTCTGTTAGGATAGAAATCGATGGATTTCCCTAAGGAGCAACAGCATGAAAAAAATCATTATTGCCGCCGGCACATTGGT
GCTGGCCGGCTGCAGCTATG

Product: anhydro-N-acetylmuramic acid kinase

Products: NA

Alternate protein names: AnhMurNAc kinase

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKSGRYIGVMSGTSLDGVDVVLAAIDGRMVAQQASYSHPMPLQLKQDILGMCQGQQTTLSAVGRLDAQLGTLFGEAVLGL
LKQTGVAAHDITAIGCHGQTVWHEPEGDARFSMQLGDNNRIAALTNITTVGDFRRRDMAYGGQGAPLVPAFHQALLSHPV
ERRMVLNIGGIANLSMLLPGAAVRGFDTGPGNMLMDAWIWRHQSQPYDKDGGWAMAGRVCLPLLQQMLADPYFSLPAPKS
TGREYFNAAWLERQLAGLAAVSPVDVQTTLTELTAVTICEQVQLAGGCERLLVCGGGARNMLLMARMSALLPGTEVCLTD
DFGISGDDMEALAFAWLAFRTLSGQPGNLPSVTGASCETLLGGIYPVLPLGGR

Sequences:

>Translated_373_residues
MKSGRYIGVMSGTSLDGVDVVLAAIDGRMVAQQASYSHPMPLQLKQDILGMCQGQQTTLSAVGRLDAQLGTLFGEAVLGL
LKQTGVAAHDITAIGCHGQTVWHEPEGDARFSMQLGDNNRIAALTNITTVGDFRRRDMAYGGQGAPLVPAFHQALLSHPV
ERRMVLNIGGIANLSMLLPGAAVRGFDTGPGNMLMDAWIWRHQSQPYDKDGGWAMAGRVCLPLLQQMLADPYFSLPAPKS
TGREYFNAAWLERQLAGLAAVSPVDVQTTLTELTAVTICEQVQLAGGCERLLVCGGGARNMLLMARMSALLPGTEVCLTD
DFGISGDDMEALAFAWLAFRTLSGQPGNLPSVTGASCETLLGGIYPVLPLGGR
>Mature_373_residues
MKSGRYIGVMSGTSLDGVDVVLAAIDGRMVAQQASYSHPMPLQLKQDILGMCQGQQTTLSAVGRLDAQLGTLFGEAVLGL
LKQTGVAAHDITAIGCHGQTVWHEPEGDARFSMQLGDNNRIAALTNITTVGDFRRRDMAYGGQGAPLVPAFHQALLSHPV
ERRMVLNIGGIANLSMLLPGAAVRGFDTGPGNMLMDAWIWRHQSQPYDKDGGWAMAGRVCLPLLQQMLADPYFSLPAPKS
TGREYFNAAWLERQLAGLAAVSPVDVQTTLTELTAVTICEQVQLAGGCERLLVCGGGARNMLLMARMSALLPGTEVCLTD
DFGISGDDMEALAFAWLAFRTLSGQPGNLPSVTGASCETLLGGIYPVLPLGGR

Specific function: Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived

COG id: COG2377

COG function: function code O; Predicted molecular chaperone distantly related to HSP70-fold metalloproteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anhydro-N-acetylmuramic acid kinase family

Homologues:

Organism=Escherichia coli, GI1787928, Length=369, Percent_Identity=72.89972899729, Blast_Score=527, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANMK_SERP5 (A8GDX7)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478445.1
- ProteinModelPortal:   A8GDX7
- SMR:   A8GDX7
- STRING:   A8GDX7
- GeneID:   5605294
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2216
- eggNOG:   COG2377
- HOGENOM:   HBG324434
- OMA:   GSHGQTV
- ProtClustDB:   PRK09585
- BioCyc:   SPRO399741:SPRO_2216-MONOMER
- HAMAP:   MF_01270
- InterPro:   IPR005338

Pfam domain/function: PF03702 UPF0075

EC number: NA

Molecular weight: Translated: 39613; Mature: 39613

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSGRYIGVMSGTSLDGVDVVLAAIDGRMVAQQASYSHPMPLQLKQDILGMCQGQQTTLS
CCCCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHH
AVGRLDAQLGTLFGEAVLGLLKQTGVAAHDITAIGCHGQTVWHEPEGDARFSMQLGDNNR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHCEEEEECCCCEEEECCCCCCEEEEEECCCCC
IAALTNITTVGDFRRRDMAYGGQGAPLVPAFHQALLSHPVERRMVLNIGGIANLSMLLPG
EEEEEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHEEEEECCCHHHHHHHCCC
AAVRGFDTGPGNMLMDAWIWRHQSQPYDKDGGWAMAGRVCLPLLQQMLADPYFSLPAPKS
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCC
TGREYFNAAWLERQLAGLAAVSPVDVQTTLTELTAVTICEQVQLAGGCERLLVCGGGARN
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHH
MLLMARMSALLPGTEVCLTDDFGISGDDMEALAFAWLAFRTLSGQPGNLPSVTGASCETL
HHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LGGIYPVLPLGGR
HCCHHHCCCCCCC
>Mature Secondary Structure
MKSGRYIGVMSGTSLDGVDVVLAAIDGRMVAQQASYSHPMPLQLKQDILGMCQGQQTTLS
CCCCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHH
AVGRLDAQLGTLFGEAVLGLLKQTGVAAHDITAIGCHGQTVWHEPEGDARFSMQLGDNNR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHCEEEEECCCCEEEECCCCCCEEEEEECCCCC
IAALTNITTVGDFRRRDMAYGGQGAPLVPAFHQALLSHPVERRMVLNIGGIANLSMLLPG
EEEEEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHEEEEECCCHHHHHHHCCC
AAVRGFDTGPGNMLMDAWIWRHQSQPYDKDGGWAMAGRVCLPLLQQMLADPYFSLPAPKS
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCC
TGREYFNAAWLERQLAGLAAVSPVDVQTTLTELTAVTICEQVQLAGGCERLLVCGGGARN
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHH
MLLMARMSALLPGTEVCLTDDFGISGDDMEALAFAWLAFRTLSGQPGNLPSVTGASCETL
HHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LGGIYPVLPLGGR
HCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA