Click here to switch to the map view.

The map label for this gene is slyA

Identifier: 157370454

GI number: 157370454

Start: 2415925

End: 2416359

Strand: Direct

Name: slyA

Synonym: Spro_2214

Alternate gene names: 157370454

Gene position: 2415925-2416359 (Clockwise)

Preceding gene: 157370450

Following gene: 157370456

Centisome position: 44.34

GC content: 51.03

Gene sequence:

>435_bases
GTGGAGTCAACATTAGGTTCCGATTTAGCACGATTAGTTCGTGTTTGGCGCGCGCTGATCGATCATCGGCTCAAGCCGCT
GGCGCTGACGCAAACACATTGGGTAACCCTGCACAGTATCAATCGCTTACCGCCGGAGCAGTCGCAAATCCAGCTGGCCA
AGGCGATCGGCATTGAGCAACCGTCATTGGTTCGTACTCTGGACCAGTTAGAAGAAAAGGGGCTGATTACTCGCCACACC
TGCGCCAACGACCGGCGTGCGAAGCGTATCAAGCTGACTGAAGCTGCCGATCCCATTATCAGGGAGGTGGACAGCGTGAT
CAGTTCGACGCGTGGTGAAATTTTGAGTGGGATTACCACTGACGAAGTGCAATTGTTGGTAGGTTTGATTGGCAAGTTGG
AACAAAACATTACTGAACTGCAAAATAAACAATAA

Upstream 100 bases:

>100_bases
ACAATATACATTATATACATTTGTGTTTTTAATGTTAGTTACTCAAAATAGTCTAAACTCTGGGAGGGTATGTTAGCATG
CTAATTATAAGGAGGGGTAA

Downstream 100 bases:

>100_bases
GAACTTCTTCTTTATACGATTAGATTTCACAGCATCGGAAATGAAACCGGAGGCCTAAAGCCTCCGGTTTTACCCGCTAA
GTTCAGCTTACAGTGGGGAC

Product: transcriptional regulator SlyA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MESTLGSDLARLVRVWRALIDHRLKPLALTQTHWVTLHSINRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEEKGLITRHT
CANDRRAKRIKLTEAADPIIREVDSVISSTRGEILSGITTDEVQLLVGLIGKLEQNITELQNKQ

Sequences:

>Translated_144_residues
MESTLGSDLARLVRVWRALIDHRLKPLALTQTHWVTLHSINRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEEKGLITRHT
CANDRRAKRIKLTEAADPIIREVDSVISSTRGEILSGITTDEVQLLVGLIGKLEQNITELQNKQ
>Mature_144_residues
MESTLGSDLARLVRVWRALIDHRLKPLALTQTHWVTLHSINRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEEKGLITRHT
CANDRRAKRIKLTEAADPIIREVDSVISSTRGEILSGITTDEVQLLVGLIGKLEQNITELQNKQ

Specific function: Transcription regulator that can both activate or repress expression

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI87081950, Length=143, Percent_Identity=76.9230769230769, Blast_Score=224, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SLYA_SERP5 (A8GDX5)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478443.1
- ProteinModelPortal:   A8GDX5
- SMR:   A8GDX5
- STRING:   A8GDX5
- GeneID:   5605292
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2214
- eggNOG:   COG1846
- HOGENOM:   HBG728159
- OMA:   DEHRFGM
- ProtClustDB:   PRK03573
- BioCyc:   SPRO399741:SPRO_2214-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_01819
- InterPro:   IPR000835
- InterPro:   IPR023071
- InterPro:   IPR023187
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00598
- SMART:   SM00347

Pfam domain/function: PF01047 MarR

EC number: NA

Molecular weight: Translated: 16184; Mature: 16184

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS01117 HTH_MARR_1; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESTLGSDLARLVRVWRALIDHRLKPLALTQTHWVTLHSINRLPPEQSQIQLAKAIGIEQ
CCCCHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
PSLVRTLDQLEEKGLITRHTCANDRRAKRIKLTEAADPIIREVDSVISSTRGEILSGITT
HHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCH
DEVQLLVGLIGKLEQNITELQNKQ
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MESTLGSDLARLVRVWRALIDHRLKPLALTQTHWVTLHSINRLPPEQSQIQLAKAIGIEQ
CCCCHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
PSLVRTLDQLEEKGLITRHTCANDRRAKRIKLTEAADPIIREVDSVISSTRGEILSGITT
HHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCH
DEVQLLVGLIGKLEQNITELQNKQ
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA