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The map label for this gene is btuE [C]

Identifier: 157370411

GI number: 157370411

Start: 2368539

End: 2369024

Strand: Reverse

Name: btuE [C]

Synonym: Spro_2171

Alternate gene names: 157370411

Gene position: 2369024-2368539 (Counterclockwise)

Preceding gene: 157370412

Following gene: 157370410

Centisome position: 43.48

GC content: 55.97

Gene sequence:

>486_bases
ATGATCCACTCACTGTTATCCATCCCCTGCGTCACACTGCAAGGGGAACACAAAACCCTGGGCGATTTCCCCGCCCGGGC
TTATCTGGTGGTCAACACCGCCAGCAAATGCGGATTTACTCCTCAATATCACGGGCTGGAAAACCTGTGGCAGTACTATC
GCGAACGCGGCCTGATGGTGCTGGGCTTTCCCTGCAATCAGTTCGGCGCGCAGGAACCCGGCGATCCGCTGGAGATTGCC
AACTTTTGCACGCTGAACTATGGCGTCAGCTTCCCGCTATTCAGCAAGGTTGAAGTTAATGGCCCAGGCGCGCATCCGTT
GTTCAACGAATTAAAACGCCTGGCACCGGGCGTGCTGGGCACTCAACGCATTAAATGGAACTTCACCAAGTTCCTGCTGA
CCGCTGACGGCCAGCGGGTGAAACGCTACGCGCCGATCACCAAACCCGAACGCCTGTTTGACCGCATTGAAACCCTGCTG
AAATAA

Upstream 100 bases:

>100_bases
CCCAGCGCCGGGGCGCCCGCCCCGGTTTTTCCGTCTGTGCCCTGCTCATCTATACTGGTAACAATTCTTGTATCCCCCTG
AAAAGGATTTGGAGTCCGGC

Downstream 100 bases:

>100_bases
CCCTGAATTTTACGGGCTGAGCCATCTCGGCCCGTGCCACATCCCCTTCCTGCAAAAAGCTTCCATTGGTAAGAAAATTT
TCCTTGATGTAACCTTTCGT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MIHSLLSIPCVTLQGEHKTLGDFPARAYLVVNTASKCGFTPQYHGLENLWQYYRERGLMVLGFPCNQFGAQEPGDPLEIA
NFCTLNYGVSFPLFSKVEVNGPGAHPLFNELKRLAPGVLGTQRIKWNFTKFLLTADGQRVKRYAPITKPERLFDRIETLL
K

Sequences:

>Translated_161_residues
MIHSLLSIPCVTLQGEHKTLGDFPARAYLVVNTASKCGFTPQYHGLENLWQYYRERGLMVLGFPCNQFGAQEPGDPLEIA
NFCTLNYGVSFPLFSKVEVNGPGAHPLFNELKRLAPGVLGTQRIKWNFTKFLLTADGQRVKRYAPITKPERLFDRIETLL
K
>Mature_161_residues
MIHSLLSIPCVTLQGEHKTLGDFPARAYLVVNTASKCGFTPQYHGLENLWQYYRERGLMVLGFPCNQFGAQEPGDPLEIA
NFCTLNYGVSFPLFSKVEVNGPGAHPLFNELKRLAPGVLGTQRIKWNFTKFLLTADGQRVKRYAPITKPERLFDRIETLL
K

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=153, Percent_Identity=39.2156862745098, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI75709200, Length=150, Percent_Identity=43.3333333333333, Blast_Score=106, Evalue=8e-24,
Organism=Homo sapiens, GI90903240, Length=150, Percent_Identity=43.3333333333333, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI192455698, Length=161, Percent_Identity=33.5403726708075, Blast_Score=91, Evalue=4e-19,
Organism=Homo sapiens, GI90903238, Length=132, Percent_Identity=43.1818181818182, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI4557629, Length=150, Percent_Identity=38.6666666666667, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI41406084, Length=171, Percent_Identity=36.2573099415205, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI32967607, Length=167, Percent_Identity=32.9341317365269, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI6006001, Length=156, Percent_Identity=36.5384615384615, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI33186887, Length=163, Percent_Identity=35.5828220858896, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1788003, Length=169, Percent_Identity=43.7869822485207, Blast_Score=149, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17535473, Length=161, Percent_Identity=39.7515527950311, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=37.5, Blast_Score=115, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI71993584, Length=150, Percent_Identity=36.6666666666667, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI193210707, Length=152, Percent_Identity=38.8157894736842, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17550320, Length=164, Percent_Identity=30.4878048780488, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193209493, Length=164, Percent_Identity=29.2682926829268, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319721, Length=160, Percent_Identity=46.875, Blast_Score=171, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6322228, Length=151, Percent_Identity=49.0066225165563, Blast_Score=159, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6322826, Length=135, Percent_Identity=44.4444444444444, Blast_Score=125, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24656772, Length=150, Percent_Identity=45.3333333333333, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=43.125, Blast_Score=116, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=43.125, Blast_Score=116, Evalue=6e-27,
Organism=Drosophila melanogaster, GI85726443, Length=160, Percent_Identity=39.375, Blast_Score=98, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18201; Mature: 18201

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHSLLSIPCVTLQGEHKTLGDFPARAYLVVNTASKCGFTPQYHGLENLWQYYRERGLMV
CCCCHHHCCEEEECCCCCCCCCCCCEEEEEEECHHHCCCCCCCCCHHHHHHHHHHCCCEE
LGFPCNQFGAQEPGDPLEIANFCTLNYGVSFPLFSKVEVNGPGAHPLFNELKRLAPGVLG
EECCCHHCCCCCCCCHHHHHHEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCC
TQRIKWNFTKFLLTADGQRVKRYAPITKPERLFDRIETLLK
CCEEEEEEEEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MIHSLLSIPCVTLQGEHKTLGDFPARAYLVVNTASKCGFTPQYHGLENLWQYYRERGLMV
CCCCHHHCCEEEECCCCCCCCCCCCEEEEEEECHHHCCCCCCCCCHHHHHHHHHHCCCEE
LGFPCNQFGAQEPGDPLEIANFCTLNYGVSFPLFSKVEVNGPGAHPLFNELKRLAPGVLG
EECCCHHCCCCCCCCHHHHHHEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCC
TQRIKWNFTKFLLTADGQRVKRYAPITKPERLFDRIETLLK
CCEEEEEEEEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]