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The map label for this gene is aroH [H]

Identifier: 157370412

GI number: 157370412

Start: 2369126

End: 2370172

Strand: Reverse

Name: aroH [H]

Synonym: Spro_2172

Alternate gene names: 157370412

Gene position: 2370172-2369126 (Counterclockwise)

Preceding gene: 157370413

Following gene: 157370411

Centisome position: 43.5

GC content: 59.5

Gene sequence:

>1047_bases
ATGCACAAAACAGATGAACTGCGGACCGCGCGCATCGACAGCCTCGTCACGCCGCAAGAGCTGGCGGAGAAGTTGCCAAT
CTCGGCGGAAATCGCGGACAACGTGACGGCCTCACGGCAGCGAATTGAAAAAATTCTGACCGGCGAAGATCGTCGCCTGC
TGGTGGTGATCGGCCCCTGCTCTATTCACGATCTTGACGCCGCCATCGATTATGCCGGCCGGTTGAATGCGCTGCGCATC
CGTTATCAGGATCGCCTCGAAATCGTGATGCGCACCTATTTTGAAAAACCGCGCACCGTGGTGGGCTGGAAAGGCCTGAT
CTCCGATCCGGCGCTGGATGGCACCTTCCAGGTCAATCGCGGGATCGAAATGGCGCGTAGGCTGCTGCTGGAAGTGAACC
AGCTCGGCCTGCCAACCGCCACCGAGTTCCTGGACATGGTGGTCGGCCAATACATTGCTGATTTGATCAGTTGGGGCGCG
ATTGGCGCACGGACCACCGAAAGCCAGATCCACCGTGAAATGGCTTCGGCATTGTCCTGCCCGGTGGGCTTTAAAAACGG
CACCGACGGCAACACCCGTATCGCGATTGACGCCATTCGTGCGGCCCGCGCCGGCCATATGTTCCTGTCACCGGACAAGC
ACGGCCAGATGACTATCTATCAGACCAGCGGCAATCCTTATGGCCATATCATCATGCGTGGCGGCAAGACGCCGAACTAC
CACGCTACCGATGTGGTCGCCGCCTGCGACAGCCTGCGCGAATTCGATTTGCCGGAGCAACTGGTGATCGACTTCAGCCA
CGGCAACTGCCAGAAATTGCATCGTCGCCAACTGGAAGTGGCCGAAAACGTCTGCCAGCAGATCCGCGCCGGTTCCGTCG
CCGTTGCCGGCGTAATGGCAGAAAGCTTCCTGGTGGAAGGCACCCAGAAAATCGTTGCCGGTCAGCCACTGACCTATGGG
CAATCGATCACCGACCCTTGCCTGAGCTGGTCCGACAGCGAACAGCTGCTGGCCATGCTGGCCGATGCGGTAGACACCCG
CTTCTGA

Upstream 100 bases:

>100_bases
CACAGTTTCTCCGGTTGAATTCATCGGTTTTTACGTTATTGTGATCGCCATCACTTCCCGGCACTCCTGCCGCAGCGAAG
AACAGTTTTTAGAGAAAATC

Downstream 100 bases:

>100_bases
TCCCAGCGCCGGGGCGCCCGCCCCGGTTTTTCCGTCTGTGCCCTGCTCATCTATACTGGTAACAATTCTTGTATCCCCCT
GAAAAGGATTTGGAGTCCGG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MHKTDELRTARIDSLVTPQELAEKLPISAEIADNVTASRQRIEKILTGEDRRLLVVIGPCSIHDLDAAIDYAGRLNALRI
RYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGTFQVNRGIEMARRLLLEVNQLGLPTATEFLDMVVGQYIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAIDAIRAARAGHMFLSPDKHGQMTIYQTSGNPYGHIIMRGGKTPNY
HATDVVAACDSLREFDLPEQLVIDFSHGNCQKLHRRQLEVAENVCQQIRAGSVAVAGVMAESFLVEGTQKIVAGQPLTYG
QSITDPCLSWSDSEQLLAMLADAVDTRF

Sequences:

>Translated_348_residues
MHKTDELRTARIDSLVTPQELAEKLPISAEIADNVTASRQRIEKILTGEDRRLLVVIGPCSIHDLDAAIDYAGRLNALRI
RYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGTFQVNRGIEMARRLLLEVNQLGLPTATEFLDMVVGQYIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAIDAIRAARAGHMFLSPDKHGQMTIYQTSGNPYGHIIMRGGKTPNY
HATDVVAACDSLREFDLPEQLVIDFSHGNCQKLHRRQLEVAENVCQQIRAGSVAVAGVMAESFLVEGTQKIVAGQPLTYG
QSITDPCLSWSDSEQLLAMLADAVDTRF
>Mature_348_residues
MHKTDELRTARIDSLVTPQELAEKLPISAEIADNVTASRQRIEKILTGEDRRLLVVIGPCSIHDLDAAIDYAGRLNALRI
RYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGTFQVNRGIEMARRLLLEVNQLGLPTATEFLDMVVGQYIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAIDAIRAARAGHMFLSPDKHGQMTIYQTSGNPYGHIIMRGGKTPNY
HATDVVAACDSLREFDLPEQLVIDFSHGNCQKLHRRQLEVAENVCQQIRAGSVAVAGVMAESFLVEGTQKIVAGQPLTYG
QSITDPCLSWSDSEQLLAMLADAVDTRF

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787996, Length=348, Percent_Identity=79.3103448275862, Blast_Score=595, Evalue=1e-171,
Organism=Escherichia coli, GI1786969, Length=346, Percent_Identity=57.8034682080925, Blast_Score=413, Evalue=1e-117,
Organism=Escherichia coli, GI1788953, Length=340, Percent_Identity=50.5882352941176, Blast_Score=337, Evalue=5e-94,
Organism=Saccharomyces cerevisiae, GI6319726, Length=349, Percent_Identity=47.2779369627507, Blast_Score=311, Evalue=1e-85,
Organism=Saccharomyces cerevisiae, GI6320240, Length=353, Percent_Identity=43.6260623229462, Blast_Score=290, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38389; Mature: 38389

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKTDELRTARIDSLVTPQELAEKLPISAEIADNVTASRQRIEKILTGEDRRLLVVIGPC
CCCCHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SIHDLDAAIDYAGRLNALRIRYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGTFQVNR
CCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEECC
GIEMARRLLLEVNQLGLPTATEFLDMVVGQYIADLISWGAIGARTTESQIHREMASALSC
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNTRIAIDAIRAARAGHMFLSPDKHGQMTIYQTSGNPYGHIIMRGGKTPNY
CCCCCCCCCCCCEEEEEHHHHHHCCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC
HATDVVAACDSLREFDLPEQLVIDFSHGNCQKLHRRQLEVAENVCQQIRAGSVAVAGVMA
CHHHHHHHHHHHHHCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ESFLVEGTQKIVAGQPLTYGQSITDPCLSWSDSEQLLAMLADAVDTRF
HHHHHHCHHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHKTDELRTARIDSLVTPQELAEKLPISAEIADNVTASRQRIEKILTGEDRRLLVVIGPC
CCCCHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SIHDLDAAIDYAGRLNALRIRYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGTFQVNR
CCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEECC
GIEMARRLLLEVNQLGLPTATEFLDMVVGQYIADLISWGAIGARTTESQIHREMASALSC
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNTRIAIDAIRAARAGHMFLSPDKHGQMTIYQTSGNPYGHIIMRGGKTPNY
CCCCCCCCCCCCEEEEEHHHHHHCCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC
HATDVVAACDSLREFDLPEQLVIDFSHGNCQKLHRRQLEVAENVCQQIRAGSVAVAGVMA
CHHHHHHHHHHHHHCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ESFLVEGTQKIVAGQPLTYGQSITDPCLSWSDSEQLLAMLADAVDTRF
HHHHHHCHHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]