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The map label for this gene is proQ

Identifier: 157370358

GI number: 157370358

Start: 2312308

End: 2313018

Strand: Direct

Name: proQ

Synonym: Spro_2118

Alternate gene names: 157370358

Gene position: 2312308-2313018 (Clockwise)

Preceding gene: 157370357

Following gene: 157370359

Centisome position: 42.44

GC content: 55.27

Gene sequence:

>711_bases
ATGGAAAATCAACCTAAGTTGAACTCTAGTAAAGAAGTCATTGCTTTTCTTGCCGAGCGTTTTCCGCTCTGCTTTAGCGC
CGAGGGCGAAGCTCGCCCGTTGAAAATCGGTATTTTTCAGGATCTGGTCGAGCGTGTTCAGGGGGAAGAAAACCTAAGCA
AAACGCAATTGCGTTCTGCACTGCGCCTGTACACCTCAAGCTGGCGTTACCTGTACGGCGTCAAAGTTGGCGCACAGCGC
GTTGATTTGGACGGCAACCCGTGCGGTGAGCTGGAACAGCAGCATGTCGATCATGCCCGTCAACAGCTTGAAGAAGCCAA
AGCGCGAGTTCAGGCACAGCGTGCCGAGCAAAACGCCAAAAAACGTGAAGCTGCCGGTGAATCAGCCGCTGCGGAACCTC
GTCGTCCACGTCCAGCCGGTAAAAAACCTGCTGCACGTCGCGAAGGCGGAGCCGCTCCGGAGAACCGCAAGCCGCGCCCA
CAAACTCGCCCACAGCCCGCTCGCCAACCTCGTGAAGTCAAAGAGGAAAGCCAGCAGCGTCGTGTGCCAGTCACGGATAT
CTCTAAACTGCAAATTGGCCAGGAAATCAAAGTCAGAGCAGGCCAGAGTGCGATGGATGCAACCGTACTTGAAATCGCCA
AAGATGGCGTACGTGTGCAGCTCTCTTCCGGTCTGGCGATGATTGTGCGCGCAGAACACTTGCAGTTCTGA

Upstream 100 bases:

>100_bases
GTTGATCTACGGTTAACGTGGCATTTACCGATGGCGTCATTATAATGACGCCTGTTCATGCCTGCGCTGGTTGGCAAACC
CGTTGTAATCAGGAAATTTC

Downstream 100 bases:

>100_bases
TACGGAGGCCAACCAAGGCATGAACAAATTTGTCAGATTAACAGCAGTCGCGGGTCTGTTGTGGGCGGGTGTCAGTTACG
GAGCGGAACCAGCCAACATC

Product: putative solute/DNA competence effector

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MENQPKLNSSKEVIAFLAERFPLCFSAEGEARPLKIGIFQDLVERVQGEENLSKTQLRSALRLYTSSWRYLYGVKVGAQR
VDLDGNPCGELEQQHVDHARQQLEEAKARVQAQRAEQNAKKREAAGESAAAEPRRPRPAGKKPAARREGGAAPENRKPRP
QTRPQPARQPREVKEESQQRRVPVTDISKLQIGQEIKVRAGQSAMDATVLEIAKDGVRVQLSSGLAMIVRAEHLQF

Sequences:

>Translated_236_residues
MENQPKLNSSKEVIAFLAERFPLCFSAEGEARPLKIGIFQDLVERVQGEENLSKTQLRSALRLYTSSWRYLYGVKVGAQR
VDLDGNPCGELEQQHVDHARQQLEEAKARVQAQRAEQNAKKREAAGESAAAEPRRPRPAGKKPAARREGGAAPENRKPRP
QTRPQPARQPREVKEESQQRRVPVTDISKLQIGQEIKVRAGQSAMDATVLEIAKDGVRVQLSSGLAMIVRAEHLQF
>Mature_236_residues
MENQPKLNSSKEVIAFLAERFPLCFSAEGEARPLKIGIFQDLVERVQGEENLSKTQLRSALRLYTSSWRYLYGVKVGAQR
VDLDGNPCGELEQQHVDHARQQLEEAKARVQAQRAEQNAKKREAAGESAAAEPRRPRPAGKKPAARREGGAAPENRKPRP
QTRPQPARQPREVKEESQQRRVPVTDISKLQIGQEIKVRAGQSAMDATVLEIAKDGVRVQLSSGLAMIVRAEHLQF

Specific function: Not exactly known; may be a structural element that influences the osmotic activation of proP at a post-translational level

COG id: COG3109

COG function: function code T; Activator of osmoprotectant transporter ProP

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proQ family

Homologues:

Organism=Escherichia coli, GI48994892, Length=241, Percent_Identity=72.1991701244813, Blast_Score=328, Evalue=3e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PROQ_SERP5 (A8GDM9)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478347.1
- ProteinModelPortal:   A8GDM9
- SMR:   A8GDM9
- STRING:   A8GDM9
- GeneID:   5606136
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2118
- eggNOG:   COG3109
- HOGENOM:   HBG495470
- OMA:   RFPQCFS
- ProtClustDB:   PRK04950
- BioCyc:   SPRO399741:SPRO_2118-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00749
- InterPro:   IPR016103
- Gene3D:   G3DSA:1.10.1710.10
- SMART:   SM00945

Pfam domain/function: PF04352 ProQ; SSF48657 FINO

EC number: NA

Molecular weight: Translated: 26372; Mature: 26372

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQPKLNSSKEVIAFLAERFPLCFSAEGEARPLKIGIFQDLVERVQGEENLSKTQLRSA
CCCCCCCCCHHHHHHHHHHHCCEEECCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHH
LRLYTSSWRYLYGVKVGAQRVDLDGNPCGELEQQHVDHARQQLEEAKARVQAQRAEQNAK
HHHHHHCCCEEEEEEECCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KREAAGESAAAEPRRPRPAGKKPAARREGGAAPENRKPRPQTRPQPARQPREVKEESQQR
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
RVPVTDISKLQIGQEIKVRAGQSAMDATVLEIAKDGVRVQLSSGLAMIVRAEHLQF
CCCCCHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEHHHHHCC
>Mature Secondary Structure
MENQPKLNSSKEVIAFLAERFPLCFSAEGEARPLKIGIFQDLVERVQGEENLSKTQLRSA
CCCCCCCCCHHHHHHHHHHHCCEEECCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHH
LRLYTSSWRYLYGVKVGAQRVDLDGNPCGELEQQHVDHARQQLEEAKARVQAQRAEQNAK
HHHHHHCCCEEEEEEECCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KREAAGESAAAEPRRPRPAGKKPAARREGGAAPENRKPRPQTRPQPARQPREVKEESQQR
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
RVPVTDISKLQIGQEIKVRAGQSAMDATVLEIAKDGVRVQLSSGLAMIVRAEHLQF
CCCCCHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA