| Definition | Serratia proteamaculans 568 chromosome, complete genome. |
|---|---|
| Accession | NC_009832 |
| Length | 5,448,853 |
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The map label for this gene is gno [H]
Identifier: 157370294
GI number: 157370294
Start: 2245444
End: 2246190
Strand: Reverse
Name: gno [H]
Synonym: Spro_2052
Alternate gene names: 157370294
Gene position: 2246190-2245444 (Counterclockwise)
Preceding gene: 157370298
Following gene: 157370293
Centisome position: 41.22
GC content: 58.37
Gene sequence:
>747_bases ATGGACAGAGTAAAAACAGTAATTGTTACCGGCGCATCCAGCGGATTGGGCTTCGCTATTGCGCGGGCTTACCTGACGCG TGGCTACAATGTCGTGGGCAACGCACGCTCACTGGAACGTTTGCAGGCAGCGGCCAACCAACTCGGTAATCCTGCGAACC TGCTGCTGGTTCCCGGTGATATCGCCCTGCCGGAAACCGCGACCCGCCTGTTCGAACAGGCAGAAGAAAACTTTGGTCAG GTCGATATTCTGATCAATAACGCGGGGATCTTCATGTCCAAACCGGTGGCAGAGTATTCGGAGGAAGATGTCGACGCGAT GCTGGCGACCAATCTGAAAGGTTTCTTCTATCCCTCACAGGCCGCTGCCCGTCACATGGTGCCCAATGGCGCTGGCCACA TCGTCACCATCACTGCCGCCATCGCCATGCAGCCCATCAGCAAAGTCCCGGCCCTGCTGCCGATTATGGTCAAAGGCGGG TTGAACCAGGCCACCCGCGGGCTGGCGCTGGAACTGGCACCGCATAATGTGATGGTCAACGCCGTTGCTCCCGGCATCAT TGCCACTCCACTGACCATGAGCAACCCGGATGAACAAAGCCTGGCGTTTATGAAACAGATGGCCCCGACCCAACGCATCG GTCAGCCGCAGGATATTGTCGACGCGGTGCTGTACCTGACTGACTCAAGCTTTGTCACCGGCACCGTCGTTGCCGTAGAC GGCGGCACTACCGCCGGCGTCTGGTAA
Upstream 100 bases:
>100_bases CACCATGTATAAAATCAAATGACTCTGACCCCATTTTTCTCTTCATCTATAAGAATTATCGTTTCAGCCACGCAAATAAT GACTATGCAGAGAGCGGATA
Downstream 100 bases:
>100_bases TTAAGGAGAACCTGCACATGCCCTATGTCAATATTAAAGTCACCGATGAAGGCGTCACCGCCGAGCAGAAGCGCCAATTG ATTGAAGGCGTCACCGAGTT
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 248; Mature: 248
Protein sequence:
>248_residues MDRVKTVIVTGASSGLGFAIARAYLTRGYNVVGNARSLERLQAAANQLGNPANLLLVPGDIALPETATRLFEQAEENFGQ VDILINNAGIFMSKPVAEYSEEDVDAMLATNLKGFFYPSQAAARHMVPNGAGHIVTITAAIAMQPISKVPALLPIMVKGG LNQATRGLALELAPHNVMVNAVAPGIIATPLTMSNPDEQSLAFMKQMAPTQRIGQPQDIVDAVLYLTDSSFVTGTVVAVD GGTTAGVW
Sequences:
>Translated_248_residues MDRVKTVIVTGASSGLGFAIARAYLTRGYNVVGNARSLERLQAAANQLGNPANLLLVPGDIALPETATRLFEQAEENFGQ VDILINNAGIFMSKPVAEYSEEDVDAMLATNLKGFFYPSQAAARHMVPNGAGHIVTITAAIAMQPISKVPALLPIMVKGG LNQATRGLALELAPHNVMVNAVAPGIIATPLTMSNPDEQSLAFMKQMAPTQRIGQPQDIVDAVLYLTDSSFVTGTVVAVD GGTTAGVW >Mature_248_residues MDRVKTVIVTGASSGLGFAIARAYLTRGYNVVGNARSLERLQAAANQLGNPANLLLVPGDIALPETATRLFEQAEENFGQ VDILINNAGIFMSKPVAEYSEEDVDAMLATNLKGFFYPSQAAARHMVPNGAGHIVTITAAIAMQPISKVPALLPIMVKGG LNQATRGLALELAPHNVMVNAVAPGIIATPLTMSNPDEQSLAFMKQMAPTQRIGQPQDIVDAVLYLTDSSFVTGTVVAVD GGTTAGVW
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=33.8842975206612, Blast_Score=122, Evalue=2e-28, Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=32.8063241106719, Blast_Score=120, Evalue=2e-27, Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=32.9268292682927, Blast_Score=109, Evalue=3e-24, Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=32.6771653543307, Blast_Score=108, Evalue=6e-24, Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=31.3008130081301, Blast_Score=102, Evalue=2e-22, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=29.0983606557377, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=31.1740890688259, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=30.5555555555556, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI4758504, Length=245, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI109715829, Length=234, Percent_Identity=27.3504273504274, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI31542939, Length=249, Percent_Identity=25.3012048192771, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=30.7291666666667, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI4504505, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=26.6094420600858, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI83715985, Length=245, Percent_Identity=27.3469387755102, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=31.8548387096774, Blast_Score=132, Evalue=2e-32, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=33.6, Blast_Score=128, Evalue=4e-31, Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=34.0248962655602, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=30.1587301587302, Blast_Score=107, Evalue=7e-25, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=32.1285140562249, Blast_Score=103, Evalue=8e-24, Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=33.7448559670782, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=31.0204081632653, Blast_Score=97, Evalue=7e-22, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=31.7460317460317, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=28.6885245901639, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=29.5833333333333, Blast_Score=83, Evalue=1e-17, Organism=Escherichia coli, GI1787820, Length=228, Percent_Identity=26.3157894736842, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=28.0632411067194, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1789057, Length=183, Percent_Identity=26.775956284153, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=31.2741312741313, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=31.1740890688259, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=31.1538461538462, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=30.3846153846154, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=28.8461538461538, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=30.0380228136882, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI193204405, Length=259, Percent_Identity=29.7297297297297, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=30.1158301158301, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=30.6772908366534, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=28.6821705426357, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=30.3846153846154, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI72000259, Length=257, Percent_Identity=26.8482490272374, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17544670, Length=259, Percent_Identity=27.7992277992278, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17555706, Length=242, Percent_Identity=32.6446280991736, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=29.7297297297297, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=27.8625954198473, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=30.188679245283, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=29.3877551020408, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=30.8943089430894, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=28.5140562248996, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=28.9156626506024, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=27.6264591439689, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=27.2030651340996, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17508895, Length=137, Percent_Identity=31.3868613138686, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17561272, Length=235, Percent_Identity=27.2340425531915, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=26.6932270916335, Blast_Score=65, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=253, Percent_Identity=28.4584980237154, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=27.1317829457364, Blast_Score=69, Evalue=7e-13, Organism=Saccharomyces cerevisiae, GI6322067, Length=200, Percent_Identity=29, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=244, Percent_Identity=27.0491803278689, Blast_Score=62, Evalue=7e-11, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=32.6771653543307, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=32.1138211382114, Blast_Score=111, Evalue=5e-25, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=31.0756972111554, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=31.7647058823529, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=29.6296296296296, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=29.6747967479675, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24644337, Length=195, Percent_Identity=31.2820512820513, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24663911, Length=239, Percent_Identity=30.9623430962343, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI116007236, Length=235, Percent_Identity=28.0851063829787, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=26.8482490272374, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI116007238, Length=137, Percent_Identity=34.3065693430657, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI28571387, Length=238, Percent_Identity=28.9915966386555, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI21358495, Length=202, Percent_Identity=32.1782178217822, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24641232, Length=236, Percent_Identity=25, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI116007234, Length=231, Percent_Identity=29.4372294372294, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI281364494, Length=231, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI116007232, Length=191, Percent_Identity=30.8900523560209, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24584748, Length=187, Percent_Identity=28.8770053475936, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI161076933, Length=187, Percent_Identity=28.8770053475936, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI21357673, Length=190, Percent_Identity=27.3684210526316, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24648944, Length=230, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 26072; Mature: 26072
Theoretical pI: Translated: 4.95; Mature: 4.95
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 4.0 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 4.0 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDRVKTVIVTGASSGLGFAIARAYLTRGYNVVGNARSLERLQAAANQLGNPANLLLVPGD CCCEEEEEEECCCCCHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHCCCCCEEEEECCC IALPETATRLFEQAEENFGQVDILINNAGIFMSKPVAEYSEEDVDAMLATNLKGFFYPSQ CCCCHHHHHHHHHHHHCCCEEEEEEECCCEEEECCHHHHCHHHHHHHHHHCCCCEECCCH AAARHMVPNGAGHIVTITAAIAMQPISKVPALLPIMVKGGLNQATRGLALELAPHNVMVN HHHHHCCCCCCCCEEEEEHHHHHHHHHHCHHHHHHHHCCCCCHHCCCEEEEECCCEEEEE AVAPGIIATPLTMSNPDEQSLAFMKQMAPTQRIGQPQDIVDAVLYLTDSSFVTGTVVAVD EECCCEEECCCCCCCCCHHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEC GGTTAGVW CCCCCCCC >Mature Secondary Structure MDRVKTVIVTGASSGLGFAIARAYLTRGYNVVGNARSLERLQAAANQLGNPANLLLVPGD CCCEEEEEEECCCCCHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHCCCCCEEEEECCC IALPETATRLFEQAEENFGQVDILINNAGIFMSKPVAEYSEEDVDAMLATNLKGFFYPSQ CCCCHHHHHHHHHHHHCCCEEEEEEECCCEEEECCHHHHCHHHHHHHHHHCCCCEECCCH AAARHMVPNGAGHIVTITAAIAMQPISKVPALLPIMVKGGLNQATRGLALELAPHNVMVN HHHHHCCCCCCCCEEEEEHHHHHHHHHHCHHHHHHHHCCCCCHHCCCEEEEECCCEEEEE AVAPGIIATPLTMSNPDEQSLAFMKQMAPTQRIGQPQDIVDAVLYLTDSSFVTGTVVAVD EECCCEEECCCCCCCCCHHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEC GGTTAGVW CCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]