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The map label for this gene is glvC [H]

Identifier: 157370250

GI number: 157370250

Start: 2199025

End: 2200584

Strand: Reverse

Name: glvC [H]

Synonym: Spro_2008

Alternate gene names: 157370250

Gene position: 2200584-2199025 (Counterclockwise)

Preceding gene: 157370253

Following gene: 157370249

Centisome position: 40.39

GC content: 50.32

Gene sequence:

>1560_bases
ATGAAAGGTATTATCGATAATATCTTGAGCAAGCTGCAACTTTTTTCCAAAGCCATGATGGGGCCGATATTCTTCTTGCC
GGTTATTGGTTTAATCCTGGCATTAAGTTCTATTCTTACCAACGCCACACTGGTAAATGAAAACTCCGGAATTTTCCATG
TGGGGAAAATGCTCGGCGATACCTTCTGGCCATTATTTGGTAATCTCGGGTTAATATTCTGTATCGGTATTACCTATGGA
CTAGCCAGGGATAAAAAGAGCGAGGCCGCATTGGTGGCGGTAATGTGCTTTATCATGTTCCTCGGCGCCAACTCGTCTTA
TCTGCAGCTTAGTGGCCACGTAGCGCAAAAAATCAACGGCGAATTTTACGGCACCGGGCAAACCGAACTGCTGGGTTTCA
CCGTGGTGGATATGGGCATATTTCTCGGTCTGATCCTCGGCATCACTATCGCCTGGGTACATAACCGTCTGTGTAACGTC
GAACTGAACGGCGTGTTATCGGTTTATGGCGGCTCCAAACTGGTACTGATCGCCATGACGCCGGTGATTGTAATGTATGC
CATCGCCTTCAGCTATCTGTGGCCGGCTATCTCGCACGGTCTGATCTCGCTGACCGGCTTTATGAAAAGCTCCGGTTCGC
TTGGCGTATTCGTTTACGGTTTCTTCGAGAAATTCCTTATTCCCACCGGGCTGCATCACTTTATCTGGTCTCCGTTCCAG
CTCACCAGCATCGGCGGTTCGATCGTGCAGGATGGCCACACCGTTTCTGGCTCACAGGCGATTTTCCTGGCCTATATGCG
CGACCCGAGTATTTCGCCGCTGATGAATGAAGCACTGCGCTTCTCTCAGCAGGGTATGGTGACCATCTTTGGCCTGTCAG
GCGCAGCGCTGGCCTTTTACCACACCGCCAAACCGGAAAAGAAAATGCTGGCCAAGGCGATCCTGATCCCGGCCATCACC
ACCTCGATTCTGGTGGGTATCACCGAACCGATCGAGTTCACCTTCCTGTTTATTTCGCCGCTGCTGTGGGTGATCCATGC
GGTGCTGACTGCGCTGTCGCAGGTTGCCTGCAATCTGTTCGAAGTGCGGCCCTGGGGAGCCAGCGGTCTGATTGAGTTCC
TGGTGTATAACCTGCCGTTGCCGGTGGCCCTCACTCGCTGGCCGCTATATGTCGTGATTGGCCTGATTCAGTTCGCCGTC
TATTACCTGGTATTCAAAACGCTGGTGCTGAAGCTTAATTTAAAAACGCCGGGCCGCGAGGATGACGACGAGGTCAAACT
TTATTCGAAACAGGAGTATCAAAATAGTAAAAGTACGCCTAATGAATTGAGTGGAATAATTATTCGTGCGCTTGGCGGGA
AAGACAACATTATTTCCGTCGACAACTGTTTCACCCGGCTCAGGGTTGAATTAAAAGACATGCAACTGGTAGATGAAGCG
GCATTAAAAAGTACCGGTGCCAAAGGCGTGGTGAAAAATAGGCGTGAGGTTCAGGTTATTTATGGTGTCACCGTTGGCAA
GGTCAAAAACCAGGTCGAGAAGTATTTAGCAGCACTCTGA

Upstream 100 bases:

>100_bases
ATAACTTAGCCAAGGCAGAGTTTGCCCCTTTCTCTTTCGCCATCCCAGGGAGCTTTATCGTCAACGTCGTTATCCATTAA
AATATAAAAAAGGAACTGAC

Downstream 100 bases:

>100_bases
CATTTATTAATTTGGGAGATATTAAATGAAATTAACCGTTCTGGGCGGCGGCGGCGTGCGTTCGCCGTTCCTGGCCAAAT
CTATCGCCTACAACGCCCAC

Product: PTS system glucose-like transporter subunit IIB

Products: NA

Alternate protein names: Maltose permease IIC component; PTS system maltose-specific EIIC component; Maltose-specific phosphotransferase enzyme IIB component; PTS system maltose-specific EIIB component [H]

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MKGIIDNILSKLQLFSKAMMGPIFFLPVIGLILALSSILTNATLVNENSGIFHVGKMLGDTFWPLFGNLGLIFCIGITYG
LARDKKSEAALVAVMCFIMFLGANSSYLQLSGHVAQKINGEFYGTGQTELLGFTVVDMGIFLGLILGITIAWVHNRLCNV
ELNGVLSVYGGSKLVLIAMTPVIVMYAIAFSYLWPAISHGLISLTGFMKSSGSLGVFVYGFFEKFLIPTGLHHFIWSPFQ
LTSIGGSIVQDGHTVSGSQAIFLAYMRDPSISPLMNEALRFSQQGMVTIFGLSGAALAFYHTAKPEKKMLAKAILIPAIT
TSILVGITEPIEFTFLFISPLLWVIHAVLTALSQVACNLFEVRPWGASGLIEFLVYNLPLPVALTRWPLYVVIGLIQFAV
YYLVFKTLVLKLNLKTPGREDDDEVKLYSKQEYQNSKSTPNELSGIIIRALGGKDNIISVDNCFTRLRVELKDMQLVDEA
ALKSTGAKGVVKNRREVQVIYGVTVGKVKNQVEKYLAAL

Sequences:

>Translated_519_residues
MKGIIDNILSKLQLFSKAMMGPIFFLPVIGLILALSSILTNATLVNENSGIFHVGKMLGDTFWPLFGNLGLIFCIGITYG
LARDKKSEAALVAVMCFIMFLGANSSYLQLSGHVAQKINGEFYGTGQTELLGFTVVDMGIFLGLILGITIAWVHNRLCNV
ELNGVLSVYGGSKLVLIAMTPVIVMYAIAFSYLWPAISHGLISLTGFMKSSGSLGVFVYGFFEKFLIPTGLHHFIWSPFQ
LTSIGGSIVQDGHTVSGSQAIFLAYMRDPSISPLMNEALRFSQQGMVTIFGLSGAALAFYHTAKPEKKMLAKAILIPAIT
TSILVGITEPIEFTFLFISPLLWVIHAVLTALSQVACNLFEVRPWGASGLIEFLVYNLPLPVALTRWPLYVVIGLIQFAV
YYLVFKTLVLKLNLKTPGREDDDEVKLYSKQEYQNSKSTPNELSGIIIRALGGKDNIISVDNCFTRLRVELKDMQLVDEA
ALKSTGAKGVVKNRREVQVIYGVTVGKVKNQVEKYLAAL
>Mature_519_residues
MKGIIDNILSKLQLFSKAMMGPIFFLPVIGLILALSSILTNATLVNENSGIFHVGKMLGDTFWPLFGNLGLIFCIGITYG
LARDKKSEAALVAVMCFIMFLGANSSYLQLSGHVAQKINGEFYGTGQTELLGFTVVDMGIFLGLILGITIAWVHNRLCNV
ELNGVLSVYGGSKLVLIAMTPVIVMYAIAFSYLWPAISHGLISLTGFMKSSGSLGVFVYGFFEKFLIPTGLHHFIWSPFQ
LTSIGGSIVQDGHTVSGSQAIFLAYMRDPSISPLMNEALRFSQQGMVTIFGLSGAALAFYHTAKPEKKMLAKAILIPAIT
TSILVGITEPIEFTFLFISPLLWVIHAVLTALSQVACNLFEVRPWGASGLIEFLVYNLPLPVALTRWPLYVVIGLIQFAV
YYLVFKTLVLKLNLKTPGREDDDEVKLYSKQEYQNSKSTPNELSGIIIRALGGKDNIISVDNCFTRLRVELKDMQLVDEA
ALKSTGAKGVVKNRREVQVIYGVTVGKVKNQVEKYLAAL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=509, Percent_Identity=33.3988212180747, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI1787343, Length=519, Percent_Identity=31.9845857418112, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1786894, Length=527, Percent_Identity=30.3605313092979, Blast_Score=204, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010975 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 56836; Mature: 56836

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIIDNILSKLQLFSKAMMGPIFFLPVIGLILALSSILTNATLVNENSGIFHVGKMLGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEHHHHHHH
TFWPLFGNLGLIFCIGITYGLARDKKSEAALVAVMCFIMFLGANSSYLQLSGHVAQKING
HHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHCCC
EFYGTGQTELLGFTVVDMGIFLGLILGITIAWVHNRLCNVELNGVLSVYGGSKLVLIAMT
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEEECCCEEEEEHHH
PVIVMYAIAFSYLWPAISHGLISLTGFMKSSGSLGVFVYGFFEKFLIPTGLHHFIWSPFQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCHHHHCCCEE
LTSIGGSIVQDGHTVSGSQAIFLAYMRDPSISPLMNEALRFSQQGMVTIFGLSGAALAFY
EECCCCHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEE
HTAKPEKKMLAKAILIPAITTSILVGITEPIEFTFLFISPLLWVIHAVLTALSQVACNLF
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVRPWGASGLIEFLVYNLPLPVALTRWPLYVVIGLIQFAVYYLVFKTLVLKLNLKTPGRE
EECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
DDDEVKLYSKQEYQNSKSTPNELSGIIIRALGGKDNIISVDNCFTRLRVELKDMQLVDEA
CCCHHHEEEHHHHCCCCCCCHHHCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHH
ALKSTGAKGVVKNRREVQVIYGVTVGKVKNQVEKYLAAL
HHHCCCCCCHHCCCCEEEEEEECHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKGIIDNILSKLQLFSKAMMGPIFFLPVIGLILALSSILTNATLVNENSGIFHVGKMLGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEHHHHHHH
TFWPLFGNLGLIFCIGITYGLARDKKSEAALVAVMCFIMFLGANSSYLQLSGHVAQKING
HHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHCCC
EFYGTGQTELLGFTVVDMGIFLGLILGITIAWVHNRLCNVELNGVLSVYGGSKLVLIAMT
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEEECCCEEEEEHHH
PVIVMYAIAFSYLWPAISHGLISLTGFMKSSGSLGVFVYGFFEKFLIPTGLHHFIWSPFQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCHHHHCCCEE
LTSIGGSIVQDGHTVSGSQAIFLAYMRDPSISPLMNEALRFSQQGMVTIFGLSGAALAFY
EECCCCHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEE
HTAKPEKKMLAKAILIPAITTSILVGITEPIEFTFLFISPLLWVIHAVLTALSQVACNLF
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVRPWGASGLIEFLVYNLPLPVALTRWPLYVVIGLIQFAVYYLVFKTLVLKLNLKTPGRE
EECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
DDDEVKLYSKQEYQNSKSTPNELSGIIIRALGGKDNIISVDNCFTRLRVELKDMQLVDEA
CCCHHHEEEHHHHCCCCCCCHHHCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHH
ALKSTGAKGVVKNRREVQVIYGVTVGKVKNQVEKYLAAL
HHHCCCCCCHHCCCCEEEEEEECHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377; 11489864 [H]