Click here to switch to the map view.

The map label for this gene is sirB1 [H]

Identifier: 157370235

GI number: 157370235

Start: 2180714

End: 2181523

Strand: Direct

Name: sirB1 [H]

Synonym: Spro_1993

Alternate gene names: 157370235

Gene position: 2180714-2181523 (Clockwise)

Preceding gene: 157370234

Following gene: 157370236

Centisome position: 40.02

GC content: 54.2

Gene sequence:

>810_bases
ATGAGTAGCATTGCTGATTTTGAATTTAACACCGCGCTGCTGAGCGCGGGCGTGATCCTGGTTTCGCAGTCCGTGCGGCG
TGATTTCCCTACCGCCGAAGTCGAACGCAAGCTGCAACAGCTGGTCGATGAAGCACGTGCGGCGATGCCAAAGGATCTCA
GCCAGGAACAGCAACTGGACGCACTCATTGAACTGTTCTTCAAAACCTGGGGTTTTGGCGGCGCCGGCGGCGTGTATCGT
CTGTCCGACGCGATTTGGCTCGACAAGGTGCTGGAAGGGCGGCAGGGCACGCCGGTTTCCCTTGGCACCATTTTCCTGCA
CATCGCTGCGCATCTGGATTTACCGCTGTTGCCGGTGATTTTCCCCACTCAACTGATCCTGCGGGCAGACTGGCTGGATG
AAGAGATGTGGCTGATCAATCCGTTAAACGGTGAGACGCTAAACGAGCATCAACTGGAAGTGTGGATCAAGGGCAACCTG
GGTCTGGGCGCCGAGTTGGAAGACGATGATCTCGATGAGTCAGAAAACGTCATGGTGGTGCGTAAGATGCTCGATACGCT
GAAAGCCGCCCTGATGGAAGAACAACAGATGGAAATGGCGTTGCGCGCCAGCGAAACGGTGCTGTGTTTCGATCCGGATG
ACCCGTACGAAATCCGTGACCGTGGGCTGATTTACGCCCAGTTGGAATGCAACCATATCGCTATTTCCGATCTCAATTAT
TTTGTCGAACAGTGTCCTGAAGATCCGGTCAGCGAAGTGATCAAAGTACAGATCCACTCGATTGAACCGAAACAGGTCAC
GCTGCATTAA

Upstream 100 bases:

>100_bases
GTAAGAACCTGCGCACCCTGGCGTTTTTGCTGGCGTTGGGCTGTCTGTACCTGATAATTAAACTTGCCACGACGAAAATA
CCCTTTCTGATGGGATACTT

Downstream 100 bases:

>100_bases
TTCATTTGATTTAACATCAACAAAGGCGAAAGCATGAAACAGAAAGTGGTTAGCATTGGTGACATCAACGTAGCGAACGA
TCTGCCGTTTGTGCTGTTTG

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSSIADFEFNTALLSAGVILVSQSVRRDFPTAEVERKLQQLVDEARAAMPKDLSQEQQLDALIELFFKTWGFGGAGGVYR
LSDAIWLDKVLEGRQGTPVSLGTIFLHIAAHLDLPLLPVIFPTQLILRADWLDEEMWLINPLNGETLNEHQLEVWIKGNL
GLGAELEDDDLDESENVMVVRKMLDTLKAALMEEQQMEMALRASETVLCFDPDDPYEIRDRGLIYAQLECNHIAISDLNY
FVEQCPEDPVSEVIKVQIHSIEPKQVTLH

Sequences:

>Translated_269_residues
MSSIADFEFNTALLSAGVILVSQSVRRDFPTAEVERKLQQLVDEARAAMPKDLSQEQQLDALIELFFKTWGFGGAGGVYR
LSDAIWLDKVLEGRQGTPVSLGTIFLHIAAHLDLPLLPVIFPTQLILRADWLDEEMWLINPLNGETLNEHQLEVWIKGNL
GLGAELEDDDLDESENVMVVRKMLDTLKAALMEEQQMEMALRASETVLCFDPDDPYEIRDRGLIYAQLECNHIAISDLNY
FVEQCPEDPVSEVIKVQIHSIEPKQVTLH
>Mature_268_residues
SSIADFEFNTALLSAGVILVSQSVRRDFPTAEVERKLQQLVDEARAAMPKDLSQEQQLDALIELFFKTWGFGGAGGVYRL
SDAIWLDKVLEGRQGTPVSLGTIFLHIAAHLDLPLLPVIFPTQLILRADWLDEEMWLINPLNGETLNEHQLEVWIKGNLG
LGAELEDDDLDESENVMVVRKMLDTLKAALMEEQQMEMALRASETVLCFDPDDPYEIRDRGLIYAQLECNHIAISDLNYF
VEQCPEDPVSEVIKVQIHSIEPKQVTLH

Specific function: Not essential for the expression of the invasive phenotype. Required for maximal expression of sirC [H]

COG id: COG2912

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0162 family [H]

Homologues:

Organism=Escherichia coli, GI1787465, Length=269, Percent_Identity=60.5947955390335, Blast_Score=345, Evalue=1e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011990 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30372; Mature: 30241

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIADFEFNTALLSAGVILVSQSVRRDFPTAEVERKLQQLVDEARAAMPKDLSQEQQLD
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ALIELFFKTWGFGGAGGVYRLSDAIWLDKVLEGRQGTPVSLGTIFLHIAAHLDLPLLPVI
HHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
FPTQLILRADWLDEEMWLINPLNGETLNEHQLEVWIKGNLGLGAELEDDDLDESENVMVV
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHH
RKMLDTLKAALMEEQQMEMALRASETVLCFDPDDPYEIRDRGLIYAQLECNHIAISDLNY
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHCCCCCEEEEEEECCEEEEHHHHH
FVEQCPEDPVSEVIKVQIHSIEPKQVTLH
HHHHCCCCHHHHHHHHHEEECCCCEEEEC
>Mature Secondary Structure 
SSIADFEFNTALLSAGVILVSQSVRRDFPTAEVERKLQQLVDEARAAMPKDLSQEQQLD
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ALIELFFKTWGFGGAGGVYRLSDAIWLDKVLEGRQGTPVSLGTIFLHIAAHLDLPLLPVI
HHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
FPTQLILRADWLDEEMWLINPLNGETLNEHQLEVWIKGNLGLGAELEDDDLDESENVMVV
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHH
RKMLDTLKAALMEEQQMEMALRASETVLCFDPDDPYEIRDRGLIYAQLECNHIAISDLNY
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHCCCCCEEEEEEECCEEEEHHHHH
FVEQCPEDPVSEVIKVQIHSIEPKQVTLH
HHHHCCCCHHHHHHHHHEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]