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The map label for this gene is tqsA [H]

Identifier: 157370131

GI number: 157370131

Start: 2074443

End: 2075495

Strand: Direct

Name: tqsA [H]

Synonym: Spro_1889

Alternate gene names: 157370131

Gene position: 2074443-2075495 (Clockwise)

Preceding gene: 157370128

Following gene: 157370139

Centisome position: 38.07

GC content: 55.56

Gene sequence:

>1053_bases
ATGGGCCGAACCCTGTTGACCGATCGCAGCCTGCGGCTGGCCATTATGCTGGCGATGTTAGTGATTATTCTTGCCGGCGT
GAAAGCGGCCGTGGATGTTGTGGTGCCTTTCCTGCTGGCACTGTTCCTCGCGATGGTGCTGAATCCGCTGGTGGCACAGC
TCGAGCGCTGGCGGGTACCCCGGGTGCTGGGTGTGAGCTTGCTGGTGGTGGTTGTGGTGGTGTTGCTGATGCTGTTTGTC
GGTGTGCTGGGGGCATCTCTGAACGAATTTGCTCGCTCATTGCCGCAGTATCGCGGCTTGATGTTGGAAAAGTTGAGCGA
ACTGCAGCACTACGCCGACCGTTTCAACATTACCATTTCCACCGAGGCGATGCTGCAGTACGTCGATCCCAGTGCGGCGA
TGAATCTGATCACTCGCCTGTTGAGCCGGTTTTCCGGCGCGATGACCAATATCTTCCTGTTGCTGATGACCGTGGTATTT
ATGCTGTTCGAAGTGCAGCTATTACCTTACAAATTGCAGCAGGCGTTGGATAAGCCAAGTGAAGGTATGGCCAATATACA
GCGTGCGCTGGACGGCGTTACCCGTTATCTGCTGATCAAAACGGCGATCAGTCTGGCGACCGGGATTATCGTATGGGCCT
TCCTTGCGGTTATTGATGTGCGTTTTGCCTTCATCTGGGGGCTGCTGGCGTTCCTGCTGAATTATATTCCCAATATTGGC
TCGGTGATCGCCGCCGTTCCGCCGCTGATTCAGGCTCTGTTATTTAACGGATTTGGTGATGCTCTGGTAGTGGCTGCGGG
CTTTATCACCATCAATTTGGTGATTGGCAATATGCTGGAGCCGCGTGTGATGGGGCGCGGGCTGGGGCTGTCAACGCTGG
TGGTGTTCCTGTCATTGATCTTCTGGGGATGGCTGATGGGGCCGGTGGGGATGTTGCTGTCGGTGCCCCTGACCATTATT
ACCCGTATCGCGCTGGAGACCACCGAAGGTGGGCATAAATTGGCGGTGATTCTCGGTGATGGCCAGCCGGTTAAACCGCT
TACTCCGGAGTAA

Upstream 100 bases:

>100_bases
ATTCGCGGAGTAATACCTCTGCGGCCTGAAGGGAGAGTTTGCTAACATAACACTCATCTGATGGCCCTTTGGGCCTGCGC
TATTAACGCAAAGGAAATGT

Downstream 100 bases:

>100_bases
AGAAACTTTTCCCTGACTCATCACGACACCAAGGCCTTCATAGCCAGGGACCTGCTCCGGGGGGGCCAAAACGGTTAAAG
CACAAGCGGGGAAAAGTGGG

Product: putative transport protein

Products: NA

Alternate protein names: Transport of quorum-sensing signal protein [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MGRTLLTDRSLRLAIMLAMLVIILAGVKAAVDVVVPFLLALFLAMVLNPLVAQLERWRVPRVLGVSLLVVVVVVLLMLFV
GVLGASLNEFARSLPQYRGLMLEKLSELQHYADRFNITISTEAMLQYVDPSAAMNLITRLLSRFSGAMTNIFLLLMTVVF
MLFEVQLLPYKLQQALDKPSEGMANIQRALDGVTRYLLIKTAISLATGIIVWAFLAVIDVRFAFIWGLLAFLLNYIPNIG
SVIAAVPPLIQALLFNGFGDALVVAAGFITINLVIGNMLEPRVMGRGLGLSTLVVFLSLIFWGWLMGPVGMLLSVPLTII
TRIALETTEGGHKLAVILGDGQPVKPLTPE

Sequences:

>Translated_350_residues
MGRTLLTDRSLRLAIMLAMLVIILAGVKAAVDVVVPFLLALFLAMVLNPLVAQLERWRVPRVLGVSLLVVVVVVLLMLFV
GVLGASLNEFARSLPQYRGLMLEKLSELQHYADRFNITISTEAMLQYVDPSAAMNLITRLLSRFSGAMTNIFLLLMTVVF
MLFEVQLLPYKLQQALDKPSEGMANIQRALDGVTRYLLIKTAISLATGIIVWAFLAVIDVRFAFIWGLLAFLLNYIPNIG
SVIAAVPPLIQALLFNGFGDALVVAAGFITINLVIGNMLEPRVMGRGLGLSTLVVFLSLIFWGWLMGPVGMLLSVPLTII
TRIALETTEGGHKLAVILGDGQPVKPLTPE
>Mature_349_residues
GRTLLTDRSLRLAIMLAMLVIILAGVKAAVDVVVPFLLALFLAMVLNPLVAQLERWRVPRVLGVSLLVVVVVVLLMLFVG
VLGASLNEFARSLPQYRGLMLEKLSELQHYADRFNITISTEAMLQYVDPSAAMNLITRLLSRFSGAMTNIFLLLMTVVFM
LFEVQLLPYKLQQALDKPSEGMANIQRALDGVTRYLLIKTAISLATGIIVWAFLAVIDVRFAFIWGLLAFLLNYIPNIGS
VIAAVPPLIQALLFNGFGDALVVAAGFITINLVIGNMLEPRVMGRGLGLSTLVVFLSLIFWGWLMGPVGMLLSVPLTIIT
RIALETTEGGHKLAVILGDGQPVKPLTPE

Specific function: Controls the transport of the quorum-sensing signal AI-2 either by enhancing its secretion or inhibiting its uptake and consequently represses biofilm formation and motility and affects the global gene expression in biofilms [H]

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family [H]

Homologues:

Organism=Escherichia coli, GI1787885, Length=340, Percent_Identity=60, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI87082271, Length=337, Percent_Identity=52.2255192878338, Blast_Score=340, Evalue=9e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002549 [H]

Pfam domain/function: PF01594 UPF0118 [H]

EC number: NA

Molecular weight: Translated: 38223; Mature: 38092

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRTLLTDRSLRLAIMLAMLVIILAGVKAAVDVVVPFLLALFLAMVLNPLVAQLERWRVP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RVLGVSLLVVVVVVLLMLFVGVLGASLNEFARSLPQYRGLMLEKLSELQHYADRFNITIS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
TEAMLQYVDPSAAMNLITRLLSRFSGAMTNIFLLLMTVVFMLFEVQLLPYKLQQALDKPS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EGMANIQRALDGVTRYLLIKTAISLATGIIVWAFLAVIDVRFAFIWGLLAFLLNYIPNIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
SVIAAVPPLIQALLFNGFGDALVVAAGFITINLVIGNMLEPRVMGRGLGLSTLVVFLSLI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHH
FWGWLMGPVGMLLSVPLTIITRIALETTEGGHKLAVILGDGQPVKPLTPE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
GRTLLTDRSLRLAIMLAMLVIILAGVKAAVDVVVPFLLALFLAMVLNPLVAQLERWRVP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]