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The map label for this gene is rutG [H]

Identifier: 157370060

GI number: 157370060

Start: 2001806

End: 2003125

Strand: Reverse

Name: rutG [H]

Synonym: Spro_1818

Alternate gene names: 157370060

Gene position: 2003125-2001806 (Counterclockwise)

Preceding gene: 157370061

Following gene: 157370058

Centisome position: 36.76

GC content: 59.17

Gene sequence:

>1320_bases
ATGGCGAATACCTGGTTTCCCCAATGGCGCATGAAACAAGGCAGTCTGGACGGTTCGATTGTCGCGCCCGATGAACGGCT
TTCGCTGGCGCAAACGCTGGTGATGGGGTTGCAACATGCAGTGGCAATGTTTGGTGCCACGGTGCTGATGCCACTGCTGA
TGGGCTTTGACGCCAATCTGGCCATTCTGATGTCCGGCATCGGCACGCTGCTGTTTTTCCTGGTGGTGGGCGGCCGGGTG
CCAAGCTATCTCGGTTCCAGCGCGGCGTTTGTCGGGCTGGTGATCACTCTGACCGGCTACGGTGGCCAGGGCGCTAACCC
GAACATTGCACTGGCGCTCGGCGGCATTATCGCCTGTGGCCTGGTGTACCTGCTGATCGGCCTGGTGGTGATGAGCGTGG
GTACCCGTTGGATCGAACGCCTGATGCCGCCGGTGGTGACCGGTGCCGTGGTGATGGCGATTGGCCTTAACCTGGCGCCT
ATCGCGGTGCGCAGCGTTTCAGCCTCCAACTTTGACAGTTGGATGGCGGTGACCACTATTTTGTGTATTGGCTCGGTCGC
GGTATTCACCCGCGGGCTGATGCAGCGGCTGTTGATCCTGGTGGGATTGATCGCCGCCTATTTAATCTACGTGATAGCCA
CCAACGGCTTTGGGCTTGGCAAACCGGTGGATTACAGCGCACTAAGCCAGGCAGCCTGGTTCGGCCTGCCACAGTTCACC
ACGCCGGTGTTTAACCTGCACGCCATGTTGCTGATTGCTCCGGTGGCGATCATTCTGGTGGCGGAAAACCTCGGGCATGT
CAAAGCGGTGGCGGGCATGACCGGCCGCGATCTTGACCCTTATATCGGCCGCGCCTTCGTCGGCGATGGGCTGGCGACCA
TGCTATCCGGTTCGGTGGGCGGTACCGGGGTGACGACCTATGCCGAGAATATCGGCGTAATGTCAGTAACCAAAATTTAC
TCTACGTTGGTGTTTGTCGCGGCGGCGTTAGTAGCTATTGTGCTGGGGTTTTCACCAAAATTCGGCGCGCTGATCCACAC
CATTCCCGGCCCGGTTTTGGGCGGTGCTTCGGTAGTAGTGTTCGGTCTGATCGCCGTCGCCGGTGCGCGCATCTGGGTGC
AAAACAAAGTAGACCTGGGCGATAACGGCAACCTGATTATGGTTGCGGTCACGCTGGTACTGGGTGCAGGCGATTTTGCA
CTGACTATCGGTAACTTCACCATGGGCGGGATAGGCACGGCCACTTTCGGGGCCATTATCCTTAATGCCCTGCTGCGCAG
GCGTAAAGCGCTGCCGCTGGCAGACAGTGCCGTACGTTAA

Upstream 100 bases:

>100_bases
TGGCCTATTTCGACCGGCGCTACCACTCGCTGTTGAAACAATGATCGGCGCATAACCGCTCAAACACATTCACCCGCACC
CTGAAATTTTGGAGATAACG

Downstream 100 bases:

>100_bases
TAAATGACTATGGCCCGCTAAACGGGCCTTATTCGGCCAGCGCCGCCGCTTTCCCTTTGCGGCGAATACGCAGTTCGCTA
ACCAGCACCCCCAACACGAT

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MANTWFPQWRMKQGSLDGSIVAPDERLSLAQTLVMGLQHAVAMFGATVLMPLLMGFDANLAILMSGIGTLLFFLVVGGRV
PSYLGSSAAFVGLVITLTGYGGQGANPNIALALGGIIACGLVYLLIGLVVMSVGTRWIERLMPPVVTGAVVMAIGLNLAP
IAVRSVSASNFDSWMAVTTILCIGSVAVFTRGLMQRLLILVGLIAAYLIYVIATNGFGLGKPVDYSALSQAAWFGLPQFT
TPVFNLHAMLLIAPVAIILVAENLGHVKAVAGMTGRDLDPYIGRAFVGDGLATMLSGSVGGTGVTTYAENIGVMSVTKIY
STLVFVAAALVAIVLGFSPKFGALIHTIPGPVLGGASVVVFGLIAVAGARIWVQNKVDLGDNGNLIMVAVTLVLGAGDFA
LTIGNFTMGGIGTATFGAIILNALLRRRKALPLADSAVR

Sequences:

>Translated_439_residues
MANTWFPQWRMKQGSLDGSIVAPDERLSLAQTLVMGLQHAVAMFGATVLMPLLMGFDANLAILMSGIGTLLFFLVVGGRV
PSYLGSSAAFVGLVITLTGYGGQGANPNIALALGGIIACGLVYLLIGLVVMSVGTRWIERLMPPVVTGAVVMAIGLNLAP
IAVRSVSASNFDSWMAVTTILCIGSVAVFTRGLMQRLLILVGLIAAYLIYVIATNGFGLGKPVDYSALSQAAWFGLPQFT
TPVFNLHAMLLIAPVAIILVAENLGHVKAVAGMTGRDLDPYIGRAFVGDGLATMLSGSVGGTGVTTYAENIGVMSVTKIY
STLVFVAAALVAIVLGFSPKFGALIHTIPGPVLGGASVVVFGLIAVAGARIWVQNKVDLGDNGNLIMVAVTLVLGAGDFA
LTIGNFTMGGIGTATFGAIILNALLRRRKALPLADSAVR
>Mature_438_residues
ANTWFPQWRMKQGSLDGSIVAPDERLSLAQTLVMGLQHAVAMFGATVLMPLLMGFDANLAILMSGIGTLLFFLVVGGRVP
SYLGSSAAFVGLVITLTGYGGQGANPNIALALGGIIACGLVYLLIGLVVMSVGTRWIERLMPPVVTGAVVMAIGLNLAPI
AVRSVSASNFDSWMAVTTILCIGSVAVFTRGLMQRLLILVGLIAAYLIYVIATNGFGLGKPVDYSALSQAAWFGLPQFTT
PVFNLHAMLLIAPVAIILVAENLGHVKAVAGMTGRDLDPYIGRAFVGDGLATMLSGSVGGTGVTTYAENIGVMSVTKIYS
TLVFVAAALVAIVLGFSPKFGALIHTIPGPVLGGASVVVFGLIAVAGARIWVQNKVDLGDNGNLIMVAVTLVLGAGDFAL
TIGNFTMGGIGTATFGAIILNALLRRRKALPLADSAVR

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680143, Length=201, Percent_Identity=28.3582089552239, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI44680145, Length=201, Percent_Identity=28.3582089552239, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87081818, Length=428, Percent_Identity=79.4392523364486, Blast_Score=676, Evalue=0.0,
Organism=Escherichia coli, GI1788843, Length=413, Percent_Identity=37.2881355932203, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI87082181, Length=444, Percent_Identity=27.7027027027027, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI87082178, Length=409, Percent_Identity=26.6503667481663, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790087, Length=458, Percent_Identity=25.3275109170306, Blast_Score=72, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17541904, Length=219, Percent_Identity=29.6803652968037, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17542262, Length=176, Percent_Identity=31.25, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71993493, Length=168, Percent_Identity=33.9285714285714, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17542260, Length=168, Percent_Identity=33.9285714285714, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17558856, Length=181, Percent_Identity=31.4917127071823, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356175, Length=190, Percent_Identity=33.1578947368421, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45364; Mature: 45233

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTWFPQWRMKQGSLDGSIVAPDERLSLAQTLVMGLQHAVAMFGATVLMPLLMGFDANL
CCCCCCCCHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AILMSGIGTLLFFLVVGGRVPSYLGSSAAFVGLVITLTGYGGQGANPNIALALGGIIACG
HHHHHHHHHHHHHHHHCCCCHHHHCCHHHHEEEEEEEECCCCCCCCCCEEHHHHHHHHHH
LVYLLIGLVVMSVGTRWIERLMPPVVTGAVVMAIGLNLAPIAVRSVSASNFDSWMAVTTI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHH
LCIGSVAVFTRGLMQRLLILVGLIAAYLIYVIATNGFGLGKPVDYSALSQAAWFGLPQFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCC
TPVFNLHAMLLIAPVAIILVAENLGHVKAVAGMTGRDLDPYIGRAFVGDGLATMLSGSVG
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHCCCHHHHHCCCCC
GTGVTTYAENIGVMSVTKIYSTLVFVAAALVAIVLGFSPKFGALIHTIPGPVLGGASVVV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHH
FGLIAVAGARIWVQNKVDLGDNGNLIMVAVTLVLGAGDFALTIGNFTMGGIGTATFGAII
HHHHHHHCCCEEEECCCCCCCCCCEEHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
LNALLRRRKALPLADSAVR
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ANTWFPQWRMKQGSLDGSIVAPDERLSLAQTLVMGLQHAVAMFGATVLMPLLMGFDANL
CCCCCCCHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AILMSGIGTLLFFLVVGGRVPSYLGSSAAFVGLVITLTGYGGQGANPNIALALGGIIACG
HHHHHHHHHHHHHHHHCCCCHHHHCCHHHHEEEEEEEECCCCCCCCCCEEHHHHHHHHHH
LVYLLIGLVVMSVGTRWIERLMPPVVTGAVVMAIGLNLAPIAVRSVSASNFDSWMAVTTI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHH
LCIGSVAVFTRGLMQRLLILVGLIAAYLIYVIATNGFGLGKPVDYSALSQAAWFGLPQFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCC
TPVFNLHAMLLIAPVAIILVAENLGHVKAVAGMTGRDLDPYIGRAFVGDGLATMLSGSVG
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHCCCHHHHHCCCCC
GTGVTTYAENIGVMSVTKIYSTLVFVAAALVAIVLGFSPKFGALIHTIPGPVLGGASVVV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHH
FGLIAVAGARIWVQNKVDLGDNGNLIMVAVTLVLGAGDFALTIGNFTMGGIGTATFGAII
HHHHHHHCCCEEEECCCCCCCCCCEEHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
LNALLRRRKALPLADSAVR
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]