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The map label for this gene is betT [H]

Identifier: 157370047

GI number: 157370047

Start: 1988172

End: 1990166

Strand: Reverse

Name: betT [H]

Synonym: Spro_1805

Alternate gene names: 157370047

Gene position: 1990166-1988172 (Counterclockwise)

Preceding gene: 157370049

Following gene: 157370022

Centisome position: 36.52

GC content: 54.99

Gene sequence:

>1995_bases
ATGAGCCAAAACGACACTGAAATTGTGGCACGTCGTAGCCATATCAATCCTCCGGTATTTTTTATTTCTGCCGCTTTAAT
CATCGTCCTGGTGGCCTTTGCCGCCCTTTACCCCGAGTTGGCCGATCGCAAATTCAAAGCGTTGCAACTGGGTATTTTCA
CTAACGCCAGCTGGTTTTATATTCTGGCGGTGGCATTGATCCTGATGAGCGTGACCTATCTGGGTTTGTCGCGTTACGGC
AATATCAAGCTCGGGCCGGATCACGCCCAGCCAGACTTTAGCTATGTTTCCTGGTTCGCCATGCTGTTTTCCGCCGGGAT
GGGCATTGGCCTGATGTTCTTTGGCGTAGCCGAACCCGTAATGCATTACCTTTCTCCCCCAGTCGGAACGCCGGAAACAG
TGGAAGCGGCTAAACAGGCCATGCGCCTAACCTTCTTCCACTGGGGCCTGCACGCCTGGGCAATCTACGCCATCGTGGCG
TTGATTCTGGCCTTCTTCAGCTATCGCCACGACCTGCCGCTGACGCTGCGTTCCGCGCTGTATCCGATTATCGGCGATCG
CATCTATGGGCCAATTGGCCACGCGGTAGATATTTTTGCGGTGATAGGTACCGTGTTCGGTGTCGCAACCTCGCTGGGCT
ACGGTGTGTTGCAGGTTAACGCCGGTCTTAACCACCTGTTTGGCTTGCCGATCAACGCAACGGTGCAGGTGATTCTGATC
GTGGTGATCACCGGGTTGGCTACGCTGTCAGTGGTTTCCGGGCTGGATAAAGGCATCCGCATTCTGTCCGAATTGAACCT
CGGCCTGGCGGTGTTGCTGCTGGTGCTGGTGGCTGCGCTCGGCCCGACCGTGCTGCTGTTAAAATCCTTTGTCGAAAATA
CCGGCGGTTACCTTTCTGACATCGTCAGCAAGACCTTTAACCTGTATGCCTATGAGCCGAAGTCCAGTAACTGGCTGGGC
GGTTGGACACTGCTGTATTGGGGCTGGTGGTTGTCATGGTCGCCTTTCGTCGGCATGTTTATTGCCCGCGTTTCACGCGG
ACGTACCATCCGTGAATTCGTTACCGGCGTGCTGTTCGTCCCTGCCGGCTTTACGCTACTGTGGATGACCGTGTTCGGTA
ATAGTGCCATTAATCTGATCATGGCCGAAGGTGCGCGCGATTTGGCTAACACGGTGCAAAATGACGTAGCACTGGCACTG
TTCAACTTCCTGGAACACTTCCCGTTTTCTAATATCTTGTCGTTTATCGCGATGGCCATGGTGGTAGTGTTCTTCGTCAC
TTCCGCGGATTCGGGGGCGATGGTGGTAGATACCCTGGCTTCCGGGGGTACCGACCAAACTCCGGTCTGGCAGCGGATTT
TCTGGGCCGGCATGATGGGCCTGGTCGCCATTGCCTTGCTGCTCGCCGGTGGGCTGAGCGCGCTGCAAACCGTGACCATC
GCCAGTGCCCTGCCGTTCTCGATGATCTTGCTGGTGTCGATCTACGGGCTGTTAAAAGCCTTGCGTATCGATGCCCACAA
ACGCGACAGCCAGACGACGACCACGATTGCACCGACTGCCGCACGCAATCCGATCTCGTGGCAACGGCGTTTACGCAATA
TTGCCTATTTCCCTAAACGCTCACAGGTCAAACGCTTTGTCGGTGAAGTGGTTCAGCCGGCGATGGCGCTGGTGGAAGCC
GAATTGGCCAAACAGAACACCACCTCCTCGATTGACGATTCACAGGACGATCGCATCCGTTTCGAAGTTGATTTGGGTGA
AGACCTGAACTTTGTCTATGAGGTTCGCCTGCGGGCCTACATTCAACCGGCCTTTGCGTTGGCGGGCTTGAAAGACGAAG
AACGTGATGAGGAACATAAGTACTATCGGGGTGAAGTCCACCTGAAGGAAGGGGGCCAGGATTACGATGTGATGGGCTGG
ACGCAAGAACAGATCATTCACGATATTCTCGACCAGTACGAGAAACACCTGCACTTCCTGCACCTGGTACGCTAG

Upstream 100 bases:

>100_bases
CGCCGAGTTAAATTTCTCGGGCAGCCGTTCGCCCACTTTTTATGGAGCTGTTTTAAAGGATTAACCCCCATTCCCTAACG
GACTAGCTAGAAGGTATTCT

Downstream 100 bases:

>100_bases
TAGCCTGCGCTACTATTCTATTTAGCCGCCCCATCCGGGGCGGTTTTTGCTTCCAGTAAATCCCTGACATGTTGTTCACT
GTTATCGGGTTTGATGGTTC

Product: choline/carnitine/betaine transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MSQNDTEIVARRSHINPPVFFISAALIIVLVAFAALYPELADRKFKALQLGIFTNASWFYILAVALILMSVTYLGLSRYG
NIKLGPDHAQPDFSYVSWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVEAAKQAMRLTFFHWGLHAWAIYAIVA
LILAFFSYRHDLPLTLRSALYPIIGDRIYGPIGHAVDIFAVIGTVFGVATSLGYGVLQVNAGLNHLFGLPINATVQVILI
VVITGLATLSVVSGLDKGIRILSELNLGLAVLLLVLVAALGPTVLLLKSFVENTGGYLSDIVSKTFNLYAYEPKSSNWLG
GWTLLYWGWWLSWSPFVGMFIARVSRGRTIREFVTGVLFVPAGFTLLWMTVFGNSAINLIMAEGARDLANTVQNDVALAL
FNFLEHFPFSNILSFIAMAMVVVFFVTSADSGAMVVDTLASGGTDQTPVWQRIFWAGMMGLVAIALLLAGGLSALQTVTI
ASALPFSMILLVSIYGLLKALRIDAHKRDSQTTTTIAPTAARNPISWQRRLRNIAYFPKRSQVKRFVGEVVQPAMALVEA
ELAKQNTTSSIDDSQDDRIRFEVDLGEDLNFVYEVRLRAYIQPAFALAGLKDEERDEEHKYYRGEVHLKEGGQDYDVMGW
TQEQIIHDILDQYEKHLHFLHLVR

Sequences:

>Translated_664_residues
MSQNDTEIVARRSHINPPVFFISAALIIVLVAFAALYPELADRKFKALQLGIFTNASWFYILAVALILMSVTYLGLSRYG
NIKLGPDHAQPDFSYVSWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVEAAKQAMRLTFFHWGLHAWAIYAIVA
LILAFFSYRHDLPLTLRSALYPIIGDRIYGPIGHAVDIFAVIGTVFGVATSLGYGVLQVNAGLNHLFGLPINATVQVILI
VVITGLATLSVVSGLDKGIRILSELNLGLAVLLLVLVAALGPTVLLLKSFVENTGGYLSDIVSKTFNLYAYEPKSSNWLG
GWTLLYWGWWLSWSPFVGMFIARVSRGRTIREFVTGVLFVPAGFTLLWMTVFGNSAINLIMAEGARDLANTVQNDVALAL
FNFLEHFPFSNILSFIAMAMVVVFFVTSADSGAMVVDTLASGGTDQTPVWQRIFWAGMMGLVAIALLLAGGLSALQTVTI
ASALPFSMILLVSIYGLLKALRIDAHKRDSQTTTTIAPTAARNPISWQRRLRNIAYFPKRSQVKRFVGEVVQPAMALVEA
ELAKQNTTSSIDDSQDDRIRFEVDLGEDLNFVYEVRLRAYIQPAFALAGLKDEERDEEHKYYRGEVHLKEGGQDYDVMGW
TQEQIIHDILDQYEKHLHFLHLVR
>Mature_663_residues
SQNDTEIVARRSHINPPVFFISAALIIVLVAFAALYPELADRKFKALQLGIFTNASWFYILAVALILMSVTYLGLSRYGN
IKLGPDHAQPDFSYVSWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVEAAKQAMRLTFFHWGLHAWAIYAIVAL
ILAFFSYRHDLPLTLRSALYPIIGDRIYGPIGHAVDIFAVIGTVFGVATSLGYGVLQVNAGLNHLFGLPINATVQVILIV
VITGLATLSVVSGLDKGIRILSELNLGLAVLLLVLVAALGPTVLLLKSFVENTGGYLSDIVSKTFNLYAYEPKSSNWLGG
WTLLYWGWWLSWSPFVGMFIARVSRGRTIREFVTGVLFVPAGFTLLWMTVFGNSAINLIMAEGARDLANTVQNDVALALF
NFLEHFPFSNILSFIAMAMVVVFFVTSADSGAMVVDTLASGGTDQTPVWQRIFWAGMMGLVAIALLLAGGLSALQTVTIA
SALPFSMILLVSIYGLLKALRIDAHKRDSQTTTTIAPTAARNPISWQRRLRNIAYFPKRSQVKRFVGEVVQPAMALVEAE
LAKQNTTSSIDDSQDDRIRFEVDLGEDLNFVYEVRLRAYIQPAFALAGLKDEERDEEHKYYRGEVHLKEGGQDYDVMGWT
QEQIIHDILDQYEKHLHFLHLVR

Specific function: High-affinity uptake of choline driven by a proton- motive force [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=669, Percent_Identity=42.4514200298954, Blast_Score=545, Evalue=1e-156,
Organism=Escherichia coli, GI1788102, Length=470, Percent_Identity=30, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1786224, Length=488, Percent_Identity=28.0737704918033, Blast_Score=168, Evalue=9e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 73479; Mature: 73347

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNDTEIVARRSHINPPVFFISAALIIVLVAFAALYPELADRKFKALQLGIFTNASWFY
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEECCCHHHH
ILAVALILMSVTYLGLSRYGNIKLGPDHAQPDFSYVSWFAMLFSAGMGIGLMFFGVAEPV
HHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MHYLSPPVGTPETVEAAKQAMRLTFFHWGLHAWAIYAIVALILAFFSYRHDLPLTLRSAL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YPIIGDRIYGPIGHAVDIFAVIGTVFGVATSLGYGVLQVNAGLNHLFGLPINATVQVILI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCCCHHHHHHHHH
VVITGLATLSVVSGLDKGIRILSELNLGLAVLLLVLVAALGPTVLLLKSFVENTGGYLSD
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHH
IVSKTFNLYAYEPKSSNWLGGWTLLYWGWWLSWSPFVGMFIARVSRGRTIREFVTGVLFV
HHHHHHHEEEECCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
PAGFTLLWMTVFGNSAINLIMAEGARDLANTVQNDVALALFNFLEHFPFSNILSFIAMAM
CCCHHHHHHHHHCCCHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VVVFFVTSADSGAMVVDTLASGGTDQTPVWQRIFWAGMMGLVAIALLLAGGLSALQTVTI
HHHHHHHCCCCCCEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ASALPFSMILLVSIYGLLKALRIDAHKRDSQTTTTIAPTAARNPISWQRRLRNIAYFPKR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCH
SQVKRFVGEVVQPAMALVEAELAKQNTTSSIDDSQDDRIRFEVDLGEDLNFVYEVRLRAY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
IQPAFALAGLKDEERDEEHKYYRGEVHLKEGGQDYDVMGWTQEQIIHDILDQYEKHLHFL
HHHHHHHCCCCCCCCCHHHHHEECEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
HLVR
HHCC
>Mature Secondary Structure 
SQNDTEIVARRSHINPPVFFISAALIIVLVAFAALYPELADRKFKALQLGIFTNASWFY
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEECCCHHHH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HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]