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The map label for this gene is yhcK [H]

Identifier: 157369976

GI number: 157369976

Start: 1907740

End: 1909446

Strand: Reverse

Name: yhcK [H]

Synonym: Spro_1733

Alternate gene names: 157369976

Gene position: 1909446-1907740 (Counterclockwise)

Preceding gene: 157369978

Following gene: 157369975

Centisome position: 35.04

GC content: 48.39

Gene sequence:

>1707_bases
ATGAAAGTAAAATATCTGATCTATTTTTTTACCTTTGCCCTGATGTCCTCTTTCGCCCTGTTCATTTCCGACGAGTTGGT
CGAGGCCGAAACCGGCTATCGCGACAACCAGCTTAACCTCTACAAAATTACCCGCGCCAAGCAGATTTCAGAGGCTTTTC
AGGCCACCTTATTGGCGCACCGTCTGAAACGCCTGAGCCTGGTCGATCCTCATATTACTTCGCAGCAATGGCAGGAAGCG
GATCGAATAGCTCGGGAGAAAATTGCCCGCTTTCGCCCCCATATTGACAGTGATATCTCGCAACAGCTTGGCATTCGGCA
AAAAATCGCTGCACTCTCCATGCTCAACCTGATGGAACAATTGCTCAATAGTGACAATCTGCAGCTTTCGCTCGTTACCG
ATGCCAATGCCAACGCCAACCTGTTTAATATCAACAGCGCCTACTACATTTCTCAGGCCAGCAAAAGCTATTACCGCTAT
AGCTACGACAACCGCATGGTCGATGCCGATTCCTTTCTGTTTCTGGAAGCCGTACGGCTGAATAACCGGCTGAACCTGTC
CGTCACCGAACTTATCGATCAGGTTATCGATGTCAATATCAACCCGTTGGAGCGTAAAGTCGCTTATTTGAAAGCCGTTC
AGCTCACCGGGGTATTAAGTTCATTAAGCGCCCGGCTGATATTTATGAAGCTGAGCTATAACGATGTGCAAACCACGTTC
CTGGTGAATGATATTCTTGAGCAAATATCGACCAAAAAGATCGGCCAGATTACCAACGGACTCTATACTGCCGTCGATAC
TCACAGCCTCTATCCCGCCAGTTCGATTTATCAGTACGTTAAAAACCTGACAGAGCTTTCACAACGGCTTTTCCAGCGTA
GTTTTGAAATGGAGATCGCCGCCTCTCAGCATAAGATCTATAACAGCCAGACCGCCATTTACGGCATGATTTCCCTGGGT
GGCCTGATCGCCCTGTTTATTTTTCTGCCAACGCTGGTTTACTGTTCAAATATCAGCCGCTGGTTAACGAAAACGCATAA
TAATATTTTTCGGCTGTCGCGCGGGAATATGAACATAGTGCCTAATGAGGTGTTTTACGGCCAGGAGTTAATGGCCATCA
GCGATGCCATTAAACAACTCAAACAGTATCAGTTGGAAAAGGTCACGCTAGAAAACGAAAAGCATCTGCTGATCAAAGAG
CTGGAAGCCTCTTCATTCCTTGACCCCTTGACCAACATCTATAACCGGCGCAAATTTTTCCGCGAGTGCGAATCGCTGGC
CGCCAGCAGCTACCCGCTGGCCTTCTGCCTGATTGATATTGATAACTTCAAAAATCTCAACGATAACTACGGTCACCACA
TAGGTGACCAGGTGTTGGTGGCATTCGGCAAACTGCTGCAAAGCACCTTCCGCTCCAGTGATATTTTCTGTCGCTATGGC
GGTGAGGAATTCGCCGTGATCCTCGGGAACTGTACGCTGGAGAATGCACGCGAAGTAATATCCAAGCTACGCGAGCGAAC
TCATCAATTCACCCTGACACTGGCCGATGGGCAAAAGGTCCGCTTCACTACCAGTTGCGGCATTGCACAGGTAAGCGATA
TCCGGCTGCTGCCAACGGCGATCAAACAGGCGGATGAAGCGCTCTATTTCAGTAAAAATAACGGTAAGGACCGGATCGGC
ATTTACACCCCAACCGGTTTTATCTGA

Upstream 100 bases:

>100_bases
AGCACTTTTCTGCCCGCAGCCGCTCGCTGGGTATAGTTAAGACAGCCTGGGAGACTCAATGATATAATTAGCAAATCTGG
CTCAAGGACGCGCGGTGCGT

Downstream 100 bases:

>100_bases
ATTGTTGTTTAAAATAATTAACATTATAATTTTTATGACTAATTAGCCTAAGTCATTCACCTTACAGGCTTATCTGGCTT
TTCTGCCGCCATCCTGATGG

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MKVKYLIYFFTFALMSSFALFISDELVEAETGYRDNQLNLYKITRAKQISEAFQATLLAHRLKRLSLVDPHITSQQWQEA
DRIAREKIARFRPHIDSDISQQLGIRQKIAALSMLNLMEQLLNSDNLQLSLVTDANANANLFNINSAYYISQASKSYYRY
SYDNRMVDADSFLFLEAVRLNNRLNLSVTELIDQVIDVNINPLERKVAYLKAVQLTGVLSSLSARLIFMKLSYNDVQTTF
LVNDILEQISTKKIGQITNGLYTAVDTHSLYPASSIYQYVKNLTELSQRLFQRSFEMEIAASQHKIYNSQTAIYGMISLG
GLIALFIFLPTLVYCSNISRWLTKTHNNIFRLSRGNMNIVPNEVFYGQELMAISDAIKQLKQYQLEKVTLENEKHLLIKE
LEASSFLDPLTNIYNRRKFFRECESLAASSYPLAFCLIDIDNFKNLNDNYGHHIGDQVLVAFGKLLQSTFRSSDIFCRYG
GEEFAVILGNCTLENAREVISKLRERTHQFTLTLADGQKVRFTTSCGIAQVSDIRLLPTAIKQADEALYFSKNNGKDRIG
IYTPTGFI

Sequences:

>Translated_568_residues
MKVKYLIYFFTFALMSSFALFISDELVEAETGYRDNQLNLYKITRAKQISEAFQATLLAHRLKRLSLVDPHITSQQWQEA
DRIAREKIARFRPHIDSDISQQLGIRQKIAALSMLNLMEQLLNSDNLQLSLVTDANANANLFNINSAYYISQASKSYYRY
SYDNRMVDADSFLFLEAVRLNNRLNLSVTELIDQVIDVNINPLERKVAYLKAVQLTGVLSSLSARLIFMKLSYNDVQTTF
LVNDILEQISTKKIGQITNGLYTAVDTHSLYPASSIYQYVKNLTELSQRLFQRSFEMEIAASQHKIYNSQTAIYGMISLG
GLIALFIFLPTLVYCSNISRWLTKTHNNIFRLSRGNMNIVPNEVFYGQELMAISDAIKQLKQYQLEKVTLENEKHLLIKE
LEASSFLDPLTNIYNRRKFFRECESLAASSYPLAFCLIDIDNFKNLNDNYGHHIGDQVLVAFGKLLQSTFRSSDIFCRYG
GEEFAVILGNCTLENAREVISKLRERTHQFTLTLADGQKVRFTTSCGIAQVSDIRLLPTAIKQADEALYFSKNNGKDRIG
IYTPTGFI
>Mature_568_residues
MKVKYLIYFFTFALMSSFALFISDELVEAETGYRDNQLNLYKITRAKQISEAFQATLLAHRLKRLSLVDPHITSQQWQEA
DRIAREKIARFRPHIDSDISQQLGIRQKIAALSMLNLMEQLLNSDNLQLSLVTDANANANLFNINSAYYISQASKSYYRY
SYDNRMVDADSFLFLEAVRLNNRLNLSVTELIDQVIDVNINPLERKVAYLKAVQLTGVLSSLSARLIFMKLSYNDVQTTF
LVNDILEQISTKKIGQITNGLYTAVDTHSLYPASSIYQYVKNLTELSQRLFQRSFEMEIAASQHKIYNSQTAIYGMISLG
GLIALFIFLPTLVYCSNISRWLTKTHNNIFRLSRGNMNIVPNEVFYGQELMAISDAIKQLKQYQLEKVTLENEKHLLIKE
LEASSFLDPLTNIYNRRKFFRECESLAASSYPLAFCLIDIDNFKNLNDNYGHHIGDQVLVAFGKLLQSTFRSSDIFCRYG
GEEFAVILGNCTLENAREVISKLRERTHQFTLTLADGQKVRFTTSCGIAQVSDIRLLPTAIKQADEALYFSKNNGKDRIG
IYTPTGFI

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=160, Percent_Identity=36.875, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI145693134, Length=163, Percent_Identity=31.9018404907975, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87081881, Length=171, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786584, Length=212, Percent_Identity=32.0754716981132, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788381, Length=178, Percent_Identity=31.4606741573034, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082007, Length=174, Percent_Identity=31.6091954022989, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788085, Length=174, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787056, Length=158, Percent_Identity=37.3417721518987, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081974, Length=155, Percent_Identity=31.6129032258064, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787802, Length=262, Percent_Identity=25.1908396946565, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787816, Length=160, Percent_Identity=31.875, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081977, Length=228, Percent_Identity=28.5087719298246, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787541, Length=131, Percent_Identity=32.824427480916, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788956, Length=163, Percent_Identity=27.6073619631902, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 64933; Mature: 64933

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKYLIYFFTFALMSSFALFISDELVEAETGYRDNQLNLYKITRAKQISEAFQATLLAH
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
RLKRLSLVDPHITSQQWQEADRIAREKIARFRPHIDSDISQQLGIRQKIAALSMLNLMEQ
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHH
LLNSDNLQLSLVTDANANANLFNINSAYYISQASKSYYRYSYDNRMVDADSFLFLEAVRL
HHCCCCEEEEEEECCCCCCCEEECCCEEEEECCCCCCEEEECCCCEECCCHHHHHHHHHH
NNRLNLSVTELIDQVIDVNINPLERKVAYLKAVQLTGVLSSLSARLIFMKLSYNDVQTTF
CCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHH
LVNDILEQISTKKIGQITNGLYTAVDTHSLYPASSIYQYVKNLTELSQRLFQRSFEMEIA
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASQHKIYNSQTAIYGMISLGGLIALFIFLPTLVYCSNISRWLTKTHNNIFRLSRGNMNIV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
PNEVFYGQELMAISDAIKQLKQYQLEKVTLENEKHLLIKELEASSFLDPLTNIYNRRKFF
CCCHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RECESLAASSYPLAFCLIDIDNFKNLNDNYGHHIGDQVLVAFGKLLQSTFRSSDIFCRYG
HHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GEEFAVILGNCTLENAREVISKLRERTHQFTLTLADGQKVRFTTSCGIAQVSDIRLLPTA
CCEEEEEEECCCHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEECCCCCCCCCCCHHHHH
IKQADEALYFSKNNGKDRIGIYTPTGFI
HHHHHHHEEEECCCCCCEEEEECCCCCC
>Mature Secondary Structure
MKVKYLIYFFTFALMSSFALFISDELVEAETGYRDNQLNLYKITRAKQISEAFQATLLAH
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
RLKRLSLVDPHITSQQWQEADRIAREKIARFRPHIDSDISQQLGIRQKIAALSMLNLMEQ
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHH
LLNSDNLQLSLVTDANANANLFNINSAYYISQASKSYYRYSYDNRMVDADSFLFLEAVRL
HHCCCCEEEEEEECCCCCCCEEECCCEEEEECCCCCCEEEECCCCEECCCHHHHHHHHHH
NNRLNLSVTELIDQVIDVNINPLERKVAYLKAVQLTGVLSSLSARLIFMKLSYNDVQTTF
CCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHH
LVNDILEQISTKKIGQITNGLYTAVDTHSLYPASSIYQYVKNLTELSQRLFQRSFEMEIA
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASQHKIYNSQTAIYGMISLGGLIALFIFLPTLVYCSNISRWLTKTHNNIFRLSRGNMNIV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
PNEVFYGQELMAISDAIKQLKQYQLEKVTLENEKHLLIKELEASSFLDPLTNIYNRRKFF
CCCHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RECESLAASSYPLAFCLIDIDNFKNLNDNYGHHIGDQVLVAFGKLLQSTFRSSDIFCRYG
HHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GEEFAVILGNCTLENAREVISKLRERTHQFTLTLADGQKVRFTTSCGIAQVSDIRLLPTA
CCEEEEEEECCCHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEECCCCCCCCCCCHHHHH
IKQADEALYFSKNNGKDRIGIYTPTGFI
HHHHHHHEEEECCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]