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The map label for this gene is trxB [H]

Identifier: 157369924

GI number: 157369924

Start: 1839573

End: 1840544

Strand: Reverse

Name: trxB [H]

Synonym: Spro_1681

Alternate gene names: 157369924

Gene position: 1840544-1839573 (Counterclockwise)

Preceding gene: 157369944

Following gene: 157369923

Centisome position: 33.78

GC content: 57.3

Gene sequence:

>972_bases
ATGGGCACGGCTAAACACAGCAAATTATTGATCCTGGGCTCCGGCCCGGCGGGTTATACCGCCGCAGTTTACGCAGCGCG
CGCCAACCTGAGCCCGGTATTGATTACCGGTATGGAGCAAGGGGGTCAGTTGACCACCACCACCGAAGTGGAAAACTGGC
CGGGTGATGCCGAAGGCCTGACCGGCCCGGCGCTGATGGAGCGTATGCGCGAGCATGCTGAAAAATTCCAGACAGAGATT
GTGTTTGACCACATCAACAGCGTTGACCTGCAGAACCGTCCGTTCCGCCTGTTTGGTGACAGCGGCGAATACACCTGTGA
TGCACTGATTATCGCCACTGGCGCATCGGCCCGTTACCTTGGCCTGCCTACCGAAGAAGCTTTCAAAGGCAAGGGCGTGT
CTGCCTGTGCCACCTGTGACGGTTTCTTCTACCGTAATCAGAAAGTCGCGGTGGTCGGTGGTGGCAACACTGCCGTGGAA
GAAGCGCTTTATTTGTCCAACATCGCGGCCGAAGTTCACCTGATTCACCGCCGTGACAGCTTCCGTTCAGAAAAGATCCT
GATCAACCGGCTGATGGAGAAAGTGAAAAACGGCAACATCGTGCTGCACACCGACCATACTCTGGACGAAGTGCTGGGCG
ATCAAATGGGCGTTACCGGCGTACGTATCCGTAGCACCAAAGCGGAAGACCAAACGCAGGAACTTGAACTGGCCGGCGTG
TTTATCGCCATCGGCCACAGCCCGAACACCAGCATTTTCGGTGGTCAGCTGGAACTGGAAAACGGCTACATCAAGGTGCA
GTCCGGTATTCACGGTAATGCCACCCAGACCACCATTCCAGGCGTGTTCGCCGCCGGCGACGTGATGGATCACATCTACC
GCCAGGCGATCACCTCTGCCGGGACCGGTTGTATGGCAGCGCTGGACGCTGAGCGTTATCTGGACGGCATTGCCGGCGCA
GAAGTGCTGTAA

Upstream 100 bases:

>100_bases
TCAAACAAATCGTTAACAACATCCCCTGACGCTTTTTTTAATGCTGCGTTTTCCCTACAATCGGATCCATTGTCCGCCAT
TGTGGGAAAAGAGGGTATTC

Downstream 100 bases:

>100_bases
CCACACACTGTCATTTTAAAAAGCGGCTATCACAGCCGCTTTTTTTTTCCTGTAAGTTAAGTCGGACGGTGATTCGATGC
ACAATCTTCTCCATTGGCGT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MGTAKHSKLLILGSGPAGYTAAVYAARANLSPVLITGMEQGGQLTTTTEVENWPGDAEGLTGPALMERMREHAEKFQTEI
VFDHINSVDLQNRPFRLFGDSGEYTCDALIIATGASARYLGLPTEEAFKGKGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLSNIAAEVHLIHRRDSFRSEKILINRLMEKVKNGNIVLHTDHTLDEVLGDQMGVTGVRIRSTKAEDQTQELELAGV
FIAIGHSPNTSIFGGQLELENGYIKVQSGIHGNATQTTIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGIAGA
EVL

Sequences:

>Translated_323_residues
MGTAKHSKLLILGSGPAGYTAAVYAARANLSPVLITGMEQGGQLTTTTEVENWPGDAEGLTGPALMERMREHAEKFQTEI
VFDHINSVDLQNRPFRLFGDSGEYTCDALIIATGASARYLGLPTEEAFKGKGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLSNIAAEVHLIHRRDSFRSEKILINRLMEKVKNGNIVLHTDHTLDEVLGDQMGVTGVRIRSTKAEDQTQELELAGV
FIAIGHSPNTSIFGGQLELENGYIKVQSGIHGNATQTTIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGIAGA
EVL
>Mature_322_residues
GTAKHSKLLILGSGPAGYTAAVYAARANLSPVLITGMEQGGQLTTTTEVENWPGDAEGLTGPALMERMREHAEKFQTEIV
FDHINSVDLQNRPFRLFGDSGEYTCDALIIATGASARYLGLPTEEAFKGKGVSACATCDGFFYRNQKVAVVGGGNTAVEE
ALYLSNIAAEVHLIHRRDSFRSEKILINRLMEKVKNGNIVLHTDHTLDEVLGDQMGVTGVRIRSTKAEDQTQELELAGVF
IAIGHSPNTSIFGGQLELENGYIKVQSGIHGNATQTTIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGIAGAE
VL

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=321, Percent_Identity=85.3582554517134, Blast_Score=580, Evalue=1e-167,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=33.0128205128205, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320560, Length=324, Percent_Identity=47.5308641975309, Blast_Score=289, Evalue=4e-79,
Organism=Saccharomyces cerevisiae, GI6321898, Length=321, Percent_Identity=48.2866043613707, Blast_Score=288, Evalue=6e-79,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34560; Mature: 34429

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTAKHSKLLILGSGPAGYTAAVYAARANLSPVLITGMEQGGQLTTTTEVENWPGDAEGL
CCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPALMERMREHAEKFQTEIVFDHINSVDLQNRPFRLFGDSGEYTCDALIIATGASARYL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEEEEEECCCCEEE
GLPTEEAFKGKGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLSNIAAEVHLIHRRDS
CCCCHHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCC
FRSEKILINRLMEKVKNGNIVLHTDHTLDEVLGDQMGVTGVRIRSTKAEDQTQELELAGV
CCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCEEEEECCCCCCHHHHEEEEEE
FIAIGHSPNTSIFGGQLELENGYIKVQSGIHGNATQTTIPGVFAAGDVMDHIYRQAITSA
EEEECCCCCCCEECCEEEEECCEEEEECCCCCCCCCEECCCCEEHHHHHHHHHHHHHHHC
GTGCMAALDAERYLDGIAGAEVL
CCCHHHHHCHHHHHHHCCCCCCC
>Mature Secondary Structure 
GTAKHSKLLILGSGPAGYTAAVYAARANLSPVLITGMEQGGQLTTTTEVENWPGDAEGL
CCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPALMERMREHAEKFQTEIVFDHINSVDLQNRPFRLFGDSGEYTCDALIIATGASARYL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEEEEEECCCCEEE
GLPTEEAFKGKGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLSNIAAEVHLIHRRDS
CCCCHHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCC
FRSEKILINRLMEKVKNGNIVLHTDHTLDEVLGDQMGVTGVRIRSTKAEDQTQELELAGV
CCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCEEEEECCCCCCHHHHEEEEEE
FIAIGHSPNTSIFGGQLELENGYIKVQSGIHGNATQTTIPGVFAAGDVMDHIYRQAITSA
EEEECCCCCCCEECCEEEEECCEEEEECCCCCCCCCEECCCCEEHHHHHHHHHHHHHHHC
GTGCMAALDAERYLDGIAGAEVL
CCCHHHHHCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]