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The map label for this gene is paiB [H]

Identifier: 157369709

GI number: 157369709

Start: 1598446

End: 1599078

Strand: Direct

Name: paiB [H]

Synonym: Spro_1466

Alternate gene names: 157369709

Gene position: 1598446-1599078 (Clockwise)

Preceding gene: 157369708

Following gene: 157369710

Centisome position: 29.34

GC content: 60.19

Gene sequence:

>633_bases
ATGTACCAACCCGCCTCATTTCGCGATGACCGCCTGGAAAGTCAAATTGCTCTGGTACGTGCCCACCCGCTGGGCATGTT
AATCAGCCACGGTGAACAGGGACTGGTAGCGGATCCGCTGCCGTTTTTGATTGACGCCGATGAGCAGGGCAATATTGTGT
TGCGGGCGCACCTGTCCCGCACCAATCCCCATTGGTCCTTGCTACAGACCGTGCCGGAGTGCCTGGTAGTGTTTCAGGGG
CGTGAGGGCTATGTCTCGCCGGGCTGGTATGAAACCAAGCGTCAGACCGGCAAGGTGGTGCCGACCTGGAATTACAGCGT
GGTGCAACTGAGCGGTGTGCCGCGGGTAACGGAGGACGCGGGCTGGTTGCGACAACAGCTGGACGGGTTGACGGCGTTGC
AGGAAGGCCGCCAGCCTGAACCCTGGCATATCGGCGATGCTCCGGCCAATTATATCGCTGCACAGATCCGGGGCATTGTC
GGTATCGAGATCGCCGTGACTCACCGCGAAGGCAAATGGAAGATGAGCCAGAACCGCAACGCCGAAGATGTCGAGGGGGT
GATCGCCGCGCTGAGAGCCGGTGATGTTGACCAGCAGCAACTGGCAGATGAGGTTGAGCGGCGGCGTGGATAA

Upstream 100 bases:

>100_bases
GTGGATCATCCAACAACAGCGCAAAGTGGATCTTTAGTAAAGCTGTGGCGGGTGTTATTGCTATTCATCCACCCGATAAC
GTTGAAGGATGCCTGACGTC

Downstream 100 bases:

>100_bases
GGTATGCTGGCTCCAGACTGAATCAGGGGAAAGCAGACCATGGATTACACCAAAATCATTAAAGAGATCGGCCGTGGCAA
GAACCATGCGCGCGATCTGG

Product: FMN-binding negative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MYQPASFRDDRLESQIALVRAHPLGMLISHGEQGLVADPLPFLIDADEQGNIVLRAHLSRTNPHWSLLQTVPECLVVFQG
REGYVSPGWYETKRQTGKVVPTWNYSVVQLSGVPRVTEDAGWLRQQLDGLTALQEGRQPEPWHIGDAPANYIAAQIRGIV
GIEIAVTHREGKWKMSQNRNAEDVEGVIAALRAGDVDQQQLADEVERRRG

Sequences:

>Translated_210_residues
MYQPASFRDDRLESQIALVRAHPLGMLISHGEQGLVADPLPFLIDADEQGNIVLRAHLSRTNPHWSLLQTVPECLVVFQG
REGYVSPGWYETKRQTGKVVPTWNYSVVQLSGVPRVTEDAGWLRQQLDGLTALQEGRQPEPWHIGDAPANYIAAQIRGIV
GIEIAVTHREGKWKMSQNRNAEDVEGVIAALRAGDVDQQQLADEVERRRG
>Mature_210_residues
MYQPASFRDDRLESQIALVRAHPLGMLISHGEQGLVADPLPFLIDADEQGNIVLRAHLSRTNPHWSLLQTVPECLVVFQG
REGYVSPGWYETKRQTGKVVPTWNYSVVQLSGVPRVTEDAGWLRQQLDGLTALQEGRQPEPWHIGDAPANYIAAQIRGIV
GIEIAVTHREGKWKMSQNRNAEDVEGVIAALRAGDVDQQQLADEVERRRG

Specific function: Involved in the reduction of extracellular and cell- associated protease levels, as well as in the reduced levels of alpha-amylase, levansucrase, alkaline phosphatase and sporulation inhibition, when present in high copy number [H]

COG id: COG2808

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the paiB family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322780, Length=159, Percent_Identity=35.2201257861635, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007396
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF04299 FMN_bind_2 [H]

EC number: NA

Molecular weight: Translated: 23461; Mature: 23461

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQPASFRDDRLESQIALVRAHPLGMLISHGEQGLVADPLPFLIDADEQGNIVLRAHLSR
CCCCCCCCCHHHHHHHHEEECCCHHHHHHCCCCCCEECCCCEEEECCCCCCEEEEEEECC
TNPHWSLLQTVPECLVVFQGREGYVSPGWYETKRQTGKVVPTWNYSVVQLSGVPRVTEDA
CCCCHHHHHHHHHHHEEECCCCCCCCCCEECHHHCCCCEEECCCCEEEEECCCCCCCHHH
GWLRQQLDGLTALQEGRQPEPWHIGDAPANYIAAQIRGIVGIEIAVTHREGKWKMSQNRN
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCEEEEEEEEEECCCCEECCCCCC
AEDVEGVIAALRAGDVDQQQLADEVERRRG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MYQPASFRDDRLESQIALVRAHPLGMLISHGEQGLVADPLPFLIDADEQGNIVLRAHLSR
CCCCCCCCCHHHHHHHHEEECCCHHHHHHCCCCCCEECCCCEEEECCCCCCEEEEEEECC
TNPHWSLLQTVPECLVVFQGREGYVSPGWYETKRQTGKVVPTWNYSVVQLSGVPRVTEDA
CCCCHHHHHHHHHHHEEECCCCCCCCCCEECHHHCCCCEEECCCCEEEEECCCCCCCHHH
GWLRQQLDGLTALQEGRQPEPWHIGDAPANYIAAQIRGIVGIEIAVTHREGKWKMSQNRN
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCEEEEEEEEEECCCCEECCCCCC
AEDVEGVIAALRAGDVDQQQLADEVERRRG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2108124; 9384377 [H]