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The map label for this gene is trpS [H]

Identifier: 157369649

GI number: 157369649

Start: 1531990

End: 1532997

Strand: Direct

Name: trpS [H]

Synonym: Spro_1406

Alternate gene names: 157369649

Gene position: 1531990-1532997 (Clockwise)

Preceding gene: 157369648

Following gene: 157369652

Centisome position: 28.12

GC content: 58.73

Gene sequence:

>1008_bases
ATGAGCTATACCATTCTGACCGGCGATCGTCCCACCGGCTCCCTGCATTTAGGTCACTACGTCGGGTCACTGCGCCAGCG
CGTTGAGCTGCAACAACACCATCAGCAAACGGTGCTGGTGGCGGACCTGCAGGGGCTGACCGATAACGGCAATAATCCGC
AAAAAATCAGCACCAACGTGCTTAATCTGGTCGCCGACTATCTGGCAGTCGGTATCTGTCCGCAGAAGACCACGATTTGC
CTGCAATCCGCGCTGCCGGCGCTGGCCGAACTGACCATGTATTATCTCAACCTGGTCAGCGTAGCGCGGCTGGAACGCAA
TCCGACGGTGAAAAGTGAAATCATGGAAAAAGACTTTTCCCGCAGCCTGCCGGCCGGCTTTCTGGTCTACCCGGTTAGCC
AGGCGGCGGACATTACTGCCTTTGGCGCCACTCACGTGCCGGTCGGCGACGACCAACTGCCGATGCTGGAGCAAACCAAC
GAGATTGTGCGGCGTTTCAATCACATTGTCGGCCGACAGGTCTTGACGGAGTGCCAGCCGTTGTTAAGTCACGTCAGCCG
TCTGCCGGGCCTGGACGGGCAGGGCAAGATGTCGAAGTCACGCGGTAACACCATCACCCTGGGCGCCGACGCCGATCGGG
TGCATAAGGCGGTGATGAGCATGTTTACCGATCCGGGCCACTTGAATATCAACGATCCCGGTCAGGTGGAGGGCAACATG
GTATTCACCTATCTGGATGCTTTCTGCGAGGATGCCGCGCTGGTGGCGGATCTGAAGGCACACTATCGCCGTGGTGGGTT
GGGCGACATGAAAATCAAACGCCTGTTGGAAGATTGCCTGCAAAGTCTGCTGGAGCCGATCCGCACGCGTCGGACGCAAT
ACCTGGCCGACAAGGGCGAGCTGTTGCGCATTCTGCGTCAGGGGACCCAACGCGCCGACCAGGTCAGTCGGCAAACGCTG
GGGCAGGTGAAGGCCGCATTGGGGCTGGATTTCTTTACCCTCAATTGA

Upstream 100 bases:

>100_bases
AAGGCGGCACGGGTATTCACACCTCTTTTCAATGCCGCCGGTTCTGGCGGCATTTTTATTGCGTTGATCCGGTGGTGTAT
TTACTTTCAGGAGCAAGGCA

Downstream 100 bases:

>100_bases
GTGCCGGCCCTCTGTTGGGTGAGCGTCAGGCGGCGCTGTCAACGATCGGGTGTTTAACCACGAAGATATACGACAGCGCG
CCGATGACGGTAAAACAGGA

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSYTILTGDRPTGSLHLGHYVGSLRQRVELQQHHQQTVLVADLQGLTDNGNNPQKISTNVLNLVADYLAVGICPQKTTIC
LQSALPALAELTMYYLNLVSVARLERNPTVKSEIMEKDFSRSLPAGFLVYPVSQAADITAFGATHVPVGDDQLPMLEQTN
EIVRRFNHIVGRQVLTECQPLLSHVSRLPGLDGQGKMSKSRGNTITLGADADRVHKAVMSMFTDPGHLNINDPGQVEGNM
VFTYLDAFCEDAALVADLKAHYRRGGLGDMKIKRLLEDCLQSLLEPIRTRRTQYLADKGELLRILRQGTQRADQVSRQTL
GQVKAALGLDFFTLN

Sequences:

>Translated_335_residues
MSYTILTGDRPTGSLHLGHYVGSLRQRVELQQHHQQTVLVADLQGLTDNGNNPQKISTNVLNLVADYLAVGICPQKTTIC
LQSALPALAELTMYYLNLVSVARLERNPTVKSEIMEKDFSRSLPAGFLVYPVSQAADITAFGATHVPVGDDQLPMLEQTN
EIVRRFNHIVGRQVLTECQPLLSHVSRLPGLDGQGKMSKSRGNTITLGADADRVHKAVMSMFTDPGHLNINDPGQVEGNM
VFTYLDAFCEDAALVADLKAHYRRGGLGDMKIKRLLEDCLQSLLEPIRTRRTQYLADKGELLRILRQGTQRADQVSRQTL
GQVKAALGLDFFTLN
>Mature_334_residues
SYTILTGDRPTGSLHLGHYVGSLRQRVELQQHHQQTVLVADLQGLTDNGNNPQKISTNVLNLVADYLAVGICPQKTTICL
QSALPALAELTMYYLNLVSVARLERNPTVKSEIMEKDFSRSLPAGFLVYPVSQAADITAFGATHVPVGDDQLPMLEQTNE
IVRRFNHIVGRQVLTECQPLLSHVSRLPGLDGQGKMSKSRGNTITLGADADRVHKAVMSMFTDPGHLNINDPGQVEGNMV
FTYLDAFCEDAALVADLKAHYRRGGLGDMKIKRLLEDCLQSLLEPIRTRRTQYLADKGELLRILRQGTQRADQVSRQTLG
QVKAALGLDFFTLN

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=335, Percent_Identity=26.2686567164179, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI41352700, Length=169, Percent_Identity=31.9526627218935, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1789786, Length=333, Percent_Identity=27.6276276276276, Blast_Score=115, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71982800, Length=335, Percent_Identity=25.3731343283582, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71982793, Length=335, Percent_Identity=25.3731343283582, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320474, Length=352, Percent_Identity=28.125, Blast_Score=106, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24666151, Length=334, Percent_Identity=32.0359281437126, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37003; Mature: 36872

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTILTGDRPTGSLHLGHYVGSLRQRVELQQHHQQTVLVADLQGLTDNGNNPQKISTNV
CCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHH
LNLVADYLAVGICPQKTTICLQSALPALAELTMYYLNLVSVARLERNPTVKSEIMEKDFS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RSLPAGFLVYPVSQAADITAFGATHVPVGDDQLPMLEQTNEIVRRFNHIVGRQVLTECQP
HCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSHVSRLPGLDGQGKMSKSRGNTITLGADADRVHKAVMSMFTDPGHLNINDPGQVEGNM
HHHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VFTYLDAFCEDAALVADLKAHYRRGGLGDMKIKRLLEDCLQSLLEPIRTRRTQYLADKGE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRILRQGTQRADQVSRQTLGQVKAALGLDFFTLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure 
SYTILTGDRPTGSLHLGHYVGSLRQRVELQQHHQQTVLVADLQGLTDNGNNPQKISTNV
CEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHH
LNLVADYLAVGICPQKTTICLQSALPALAELTMYYLNLVSVARLERNPTVKSEIMEKDFS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RSLPAGFLVYPVSQAADITAFGATHVPVGDDQLPMLEQTNEIVRRFNHIVGRQVLTECQP
HCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSHVSRLPGLDGQGKMSKSRGNTITLGADADRVHKAVMSMFTDPGHLNINDPGQVEGNM
HHHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VFTYLDAFCEDAALVADLKAHYRRGGLGDMKIKRLLEDCLQSLLEPIRTRRTQYLADKGE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRILRQGTQRADQVSRQTLGQVKAALGLDFFTLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA