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The map label for this gene is lsrK [H]

Identifier: 157369625

GI number: 157369625

Start: 1510879

End: 1512444

Strand: Reverse

Name: lsrK [H]

Synonym: Spro_1382

Alternate gene names: 157369625

Gene position: 1512444-1510879 (Counterclockwise)

Preceding gene: 157369628

Following gene: 157369624

Centisome position: 27.76

GC content: 60.03

Gene sequence:

>1566_bases
ATGGATAACTATTTGATGGCGCTGGACGCAGGTACCGGTAGCATTCGCGCGGTCATCTTCAGTCTAGCAGGCAATCAGAT
CGCTCAGGGCCAGGCGGAATGGCGGCATCTGGCGGTGCCGGGGGTGCCCGGCTCGATGGAGTTTGACCTGGCCCATAACT
GGCAACTGACCTGCCAGTGCATTCGCCAGGCGCTGCAAAACGCCGGTATTTCCGGCCAGGCGATCCGTTCCATCGCCTGT
TGCTCGATGCGCGAAGGCATAGTGCTTTACGATCGCGACGGCACGCCGATCTGGGCCTGCGCCAACGTTGACGCGCGCGC
CAGCGAGGAGGTCAGCGAGCTGAAAGAGCTGCATAACCATAATTTCGAACGTGAGGTTTACCAATATTCGGGCCAAACGT
TGGCGTTAAGCGCCATGCCGCGCCTGTTGTGGCTGGCGCATCACCGGCCGGATATTTACCGTCAGGCCGCGACGCTGACC
ATGATCAGTGACTGGCTGGCGAACATGCTGAGCGGTGAACTGGCGGTCGATCCTTCCAACGCCGGGACTACCGGCATGCT
GGATTTGGTCAGCCGTGACTGGCGACCGGCGTTGCTCGACATGGCCGGGCTACGCGCCGATATGCTGTCACCGGTGAAAG
AAACCGGCAGCGTACTGGGACACGTCACCGAACAGGCGGCCCAACAAAGTGGCCTGCTGCGCGGTACGCCGGTAGTGATG
GGCGGCGGCGATGTGCAACTGGGTAGCCTTGGGTTGGGGGTGGTGCATGCCGGGCAAACTGCGGTATTGGGGGGTACCTT
CTGGCAACAAATCGTCAATCTGCCGGAGCCGGCCACCGATCCGGAGATGAACATCCGTATCAATCCGCATGTGATCCCGG
GTATGGCGCAAGCAGAGTCGATCAGCTTCTTCACCGGATTGACCATGCGCTGGTTCCGCGATGCCTTCTGCGCCGAAGAA
AAACTGATGGCAGAACGGCTGGGCGTGGATGCCTACAGCCTGATGGAAGAGATGGCTGCACGTGTCCCCCCAGGGGCCTA
CGGAGTGATGCCAATCTTCTCCGATGCCATGCATTTCAAAACCTGGTACCACGCCGCGCCTTCGTTTATCAATCTGTCGC
TCGACCCGGAACGCTGCAACAAACAAACGCTGTTTCGTGCACTGGAAGAGAACGCCGCGATTGTTTCGGCTTGCAATCTG
GAGCAGATCGCCCGTTTTTCCGGCGTACAGGCACGTTCACTGGTGTTCGCCGGCGGTGGTTCGAAGGGTAAGCTGTGGAG
CCAAATTCTCAGCGACGTGACTGGCCTGACGGTGCGCGTGCCGGTGGTGAAAGAAGCCACTGCGCTGGGCTGTGCGATTG
CTGCCGGCGTGGGAGCCGGGCTGTATGAGTCGCTGGCACAAACCGGCGAGCAACTGGTGCGCTGGGAGCGTGAGTATCAG
CCGGATATGGCCAATCATCAGCTGTACCAACGACAAAAAGAAACCTGGCAGCAGGTCTATGCCGACCAGCTAACCCTGGT
AGACCATGGCCTGACCACTTCGATGTGGAAGGCGCCGGGATTGTGA

Upstream 100 bases:

>100_bases
GCAGCACAGTTCACAAATCCTGCCGGCCTCGCCGTTTCCCTCATCAGTACAAAGTACAGGCCATCTATAGTTAAGATCCC
AACCCCAGAGAGTGTGAGCT

Downstream 100 bases:

>100_bases
ATCTGGTTTGGGCACAGCCTGCTGCGCCCATCACATAAGCTTATGCCAATTAAGCATTTTACCGGCCGATTGGCTGCCAA
CCGCCGCTATGCTTGCCTCG

Product: autoinducer-2 (AI-2) kinase

Products: NA

Alternate protein names: AI-2 kinase [H]

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MDNYLMALDAGTGSIRAVIFSLAGNQIAQGQAEWRHLAVPGVPGSMEFDLAHNWQLTCQCIRQALQNAGISGQAIRSIAC
CSMREGIVLYDRDGTPIWACANVDARASEEVSELKELHNHNFEREVYQYSGQTLALSAMPRLLWLAHHRPDIYRQAATLT
MISDWLANMLSGELAVDPSNAGTTGMLDLVSRDWRPALLDMAGLRADMLSPVKETGSVLGHVTEQAAQQSGLLRGTPVVM
GGGDVQLGSLGLGVVHAGQTAVLGGTFWQQIVNLPEPATDPEMNIRINPHVIPGMAQAESISFFTGLTMRWFRDAFCAEE
KLMAERLGVDAYSLMEEMAARVPPGAYGVMPIFSDAMHFKTWYHAAPSFINLSLDPERCNKQTLFRALEENAAIVSACNL
EQIARFSGVQARSLVFAGGGSKGKLWSQILSDVTGLTVRVPVVKEATALGCAIAAGVGAGLYESLAQTGEQLVRWEREYQ
PDMANHQLYQRQKETWQQVYADQLTLVDHGLTTSMWKAPGL

Sequences:

>Translated_521_residues
MDNYLMALDAGTGSIRAVIFSLAGNQIAQGQAEWRHLAVPGVPGSMEFDLAHNWQLTCQCIRQALQNAGISGQAIRSIAC
CSMREGIVLYDRDGTPIWACANVDARASEEVSELKELHNHNFEREVYQYSGQTLALSAMPRLLWLAHHRPDIYRQAATLT
MISDWLANMLSGELAVDPSNAGTTGMLDLVSRDWRPALLDMAGLRADMLSPVKETGSVLGHVTEQAAQQSGLLRGTPVVM
GGGDVQLGSLGLGVVHAGQTAVLGGTFWQQIVNLPEPATDPEMNIRINPHVIPGMAQAESISFFTGLTMRWFRDAFCAEE
KLMAERLGVDAYSLMEEMAARVPPGAYGVMPIFSDAMHFKTWYHAAPSFINLSLDPERCNKQTLFRALEENAAIVSACNL
EQIARFSGVQARSLVFAGGGSKGKLWSQILSDVTGLTVRVPVVKEATALGCAIAAGVGAGLYESLAQTGEQLVRWEREYQ
PDMANHQLYQRQKETWQQVYADQLTLVDHGLTTSMWKAPGL
>Mature_521_residues
MDNYLMALDAGTGSIRAVIFSLAGNQIAQGQAEWRHLAVPGVPGSMEFDLAHNWQLTCQCIRQALQNAGISGQAIRSIAC
CSMREGIVLYDRDGTPIWACANVDARASEEVSELKELHNHNFEREVYQYSGQTLALSAMPRLLWLAHHRPDIYRQAATLT
MISDWLANMLSGELAVDPSNAGTTGMLDLVSRDWRPALLDMAGLRADMLSPVKETGSVLGHVTEQAAQQSGLLRGTPVVM
GGGDVQLGSLGLGVVHAGQTAVLGGTFWQQIVNLPEPATDPEMNIRINPHVIPGMAQAESISFFTGLTMRWFRDAFCAEE
KLMAERLGVDAYSLMEEMAARVPPGAYGVMPIFSDAMHFKTWYHAAPSFINLSLDPERCNKQTLFRALEENAAIVSACNL
EQIARFSGVQARSLVFAGGGSKGKLWSQILSDVTGLTVRVPVVKEATALGCAIAAGVGAGLYESLAQTGEQLVRWEREYQ
PDMANHQLYQRQKETWQQVYADQLTLVDHGLTTSMWKAPGL

Specific function: Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2 [H]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787789, Length=518, Percent_Identity=78.5714285714286, Blast_Score=867, Evalue=0.0,
Organism=Escherichia coli, GI1790005, Length=509, Percent_Identity=26.3261296660118, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790361, Length=495, Percent_Identity=26.6666666666667, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789138, Length=496, Percent_Identity=24.5967741935484, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789168, Length=493, Percent_Identity=24.1379310344828, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1789987, Length=517, Percent_Identity=23.9845261121857, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17535599, Length=473, Percent_Identity=25.7928118393235, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018484 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: NA

Molecular weight: Translated: 56835; Mature: 56835

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNYLMALDAGTGSIRAVIFSLAGNQIAQGQAEWRHLAVPGVPGSMEFDLAHNWQLTCQC
CCCEEEEEECCCCHHHHHHHHHHCCHHHCCCHHHHEEECCCCCCCEEEEECCCCHHHHHH
IRQALQNAGISGQAIRSIACCSMREGIVLYDRDGTPIWACANVDARASEEVSELKELHNH
HHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHCC
NFEREVYQYSGQTLALSAMPRLLWLAHHRPDIYRQAATLTMISDWLANMLSGELAVDPSN
CHHHHHHHHCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
AGTTGMLDLVSRDWRPALLDMAGLRADMLSPVKETGSVLGHVTEQAAQQSGLLRGTPVVM
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
GGGDVQLGSLGLGVVHAGQTAVLGGTFWQQIVNLPEPATDPEMNIRINPHVIPGMAQAES
CCCCEEECCCCEEEEECCCEEEECHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHH
ISFFTGLTMRWFRDAFCAEEKLMAERLGVDAYSLMEEMAARVPPGAYGVMPIFSDAMHFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
TWYHAAPSFINLSLDPERCNKQTLFRALEENAAIVSACNLEQIARFSGVQARSLVFAGGG
HHHHCCCCEEEEECCHHHCCHHHHHHHHHCCCCEEECCCHHHHHHHCCCCEEEEEEECCC
SKGKLWSQILSDVTGLTVRVPVVKEATALGCAIAAGVGAGLYESLAQTGEQLVRWEREYQ
CCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
PDMANHQLYQRQKETWQQVYADQLTLVDHGLTTSMWKAPGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure
MDNYLMALDAGTGSIRAVIFSLAGNQIAQGQAEWRHLAVPGVPGSMEFDLAHNWQLTCQC
CCCEEEEEECCCCHHHHHHHHHHCCHHHCCCHHHHEEECCCCCCCEEEEECCCCHHHHHH
IRQALQNAGISGQAIRSIACCSMREGIVLYDRDGTPIWACANVDARASEEVSELKELHNH
HHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHCC
NFEREVYQYSGQTLALSAMPRLLWLAHHRPDIYRQAATLTMISDWLANMLSGELAVDPSN
CHHHHHHHHCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
AGTTGMLDLVSRDWRPALLDMAGLRADMLSPVKETGSVLGHVTEQAAQQSGLLRGTPVVM
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
GGGDVQLGSLGLGVVHAGQTAVLGGTFWQQIVNLPEPATDPEMNIRINPHVIPGMAQAES
CCCCEEECCCCEEEEECCCEEEECHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHH
ISFFTGLTMRWFRDAFCAEEKLMAERLGVDAYSLMEEMAARVPPGAYGVMPIFSDAMHFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
TWYHAAPSFINLSLDPERCNKQTLFRALEENAAIVSACNLEQIARFSGVQARSLVFAGGG
HHHHCCCCEEEEECCHHHCCHHHHHHHHHCCCCEEECCCHHHHHHHCCCCEEEEEEECCC
SKGKLWSQILSDVTGLTVRVPVVKEATALGCAIAAGVGAGLYESLAQTGEQLVRWEREYQ
CCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
PDMANHQLYQRQKETWQQVYADQLTLVDHGLTTSMWKAPGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA