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The map label for this gene is opdE [H]

Identifier: 157369624

GI number: 157369624

Start: 1509459

End: 1510643

Strand: Reverse

Name: opdE [H]

Synonym: Spro_1381

Alternate gene names: 157369624

Gene position: 1510643-1509459 (Counterclockwise)

Preceding gene: 157369625

Following gene: 157369623

Centisome position: 27.72

GC content: 62.62

Gene sequence:

>1185_bases
ATGCTGAATAATAATGATAAACCTGCACCATCAGCCTGGCTGGCGATTTTCTCACTGACGGTCGCCTGCTTTGTGATGGT
CACCACCGAGTTTCTGCCGATCGGCCTGCTAACCAACATCGCGCCGTCGCTGGATGTCAGCACCGGCAGAGCCGGCCTGA
TGGTGACCGTGCCCGGCATTATCGCGGCGATCGCCGCACCGGCACTGAGCCTGGCAGCCGGTCGGCTCGATCGTCGCCTG
CTGATGCTGGCGCTGAGCGTACTGCTGGCCATCTCCAATCTGGTTTCCGCACTGGCGGTTAACTTCCCCATGATGCTGCT
GGGCCGCGTGTTACTGGGTATCTGCGTCGGCGGCTTTTGGGCTTTCGCCGCCAACTATGGCCGCCATTTGGTGCCGGAAG
CCAGCCAGGGACGCGCCACCGCGCTGATCCTCAGCGGTATTTCGGTGGGTGCCGTATGCGGCGTCCCTGCCGGGGCCTTG
ATTGGTGACCTGTTCGGCTGGCGTGCCGCCTTCTTTGGCAGCGCGGTGCTGGCAGTCGGGGTATTGCTGGCGCAACTGCG
CCTTTTGACCTCGGTCCCCCCTACTCGCCCAGTCACCGCACGCGATCTGCTGTTACCGCTGCGCCTGCCGATGGCACGTA
CCGGGCTGATTGCCATCGTGCTGTTGTTTATCGGCCATTTTGCCGCCTATACCTACCTGAAACCGCTGCTGCAACAGGTG
TTTGTCCTCAGCCCGTCGGCGATATCACTGCAACTGCTGGCCTACGGTGCCATTGGCCTGCTGGGCACCTTCCTGGGTGA
ACGACTGGCCGAACGCAGCCTGCGTGCCACCTTTATCCTGATCACCGCCATGTTGGCCGCTATCCTGATTGTCTCGCCGT
TCCTTAGCGGTATCGCCGGTGCCACGCTGATGGTGATGGTGTGGGGGTTGGCGTTTGGCGCCGTGCCGGTCTGCGCCACC
AACTGGATGTTCGCCGCCGTGCCACAGGCACCGGAAGCCGGTCAGGCACTGCTGGTCTGCGTGATCCAGATTGCGCTGGC
CTCCGGTGCGCTACTGGGTGGTGAAGTGGTCGACTGGCAGGGCGTCAGCAGCGCCATGCTGTTTGGCGGCGCACTCACGC
TGTCCGCCGCGCTGGTTTTCGGCCTGACCTTGCGTTCCGGCATGATTGGCGTTAAACAGTCATAA

Upstream 100 bases:

>100_bases
GCAAACGGATTTATCCGCCGCCAATGCCTGCGTAAATTGTGATCTCTGTCACTCCGCGCCCTGAGCGCGGTTTACACCTT
GAACTGGGACGAGCGGTATT

Downstream 100 bases:

>100_bases
CCATTATTTATCTACAGAAACACACCCCGGCCTCTGCCGGGGTTTTGCACTGAGAGCGCTATGGATCATCATTTACTCGC
TATCCGGGTGTTTAACCGCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MLNNNDKPAPSAWLAIFSLTVACFVMVTTEFLPIGLLTNIAPSLDVSTGRAGLMVTVPGIIAAIAAPALSLAAGRLDRRL
LMLALSVLLAISNLVSALAVNFPMMLLGRVLLGICVGGFWAFAANYGRHLVPEASQGRATALILSGISVGAVCGVPAGAL
IGDLFGWRAAFFGSAVLAVGVLLAQLRLLTSVPPTRPVTARDLLLPLRLPMARTGLIAIVLLFIGHFAAYTYLKPLLQQV
FVLSPSAISLQLLAYGAIGLLGTFLGERLAERSLRATFILITAMLAAILIVSPFLSGIAGATLMVMVWGLAFGAVPVCAT
NWMFAAVPQAPEAGQALLVCVIQIALASGALLGGEVVDWQGVSSAMLFGGALTLSAALVFGLTLRSGMIGVKQS

Sequences:

>Translated_394_residues
MLNNNDKPAPSAWLAIFSLTVACFVMVTTEFLPIGLLTNIAPSLDVSTGRAGLMVTVPGIIAAIAAPALSLAAGRLDRRL
LMLALSVLLAISNLVSALAVNFPMMLLGRVLLGICVGGFWAFAANYGRHLVPEASQGRATALILSGISVGAVCGVPAGAL
IGDLFGWRAAFFGSAVLAVGVLLAQLRLLTSVPPTRPVTARDLLLPLRLPMARTGLIAIVLLFIGHFAAYTYLKPLLQQV
FVLSPSAISLQLLAYGAIGLLGTFLGERLAERSLRATFILITAMLAAILIVSPFLSGIAGATLMVMVWGLAFGAVPVCAT
NWMFAAVPQAPEAGQALLVCVIQIALASGALLGGEVVDWQGVSSAMLFGGALTLSAALVFGLTLRSGMIGVKQS
>Mature_394_residues
MLNNNDKPAPSAWLAIFSLTVACFVMVTTEFLPIGLLTNIAPSLDVSTGRAGLMVTVPGIIAAIAAPALSLAAGRLDRRL
LMLALSVLLAISNLVSALAVNFPMMLLGRVLLGICVGGFWAFAANYGRHLVPEASQGRATALILSGISVGAVCGVPAGAL
IGDLFGWRAAFFGSAVLAVGVLLAQLRLLTSVPPTRPVTARDLLLPLRLPMARTGLIAIVLLFIGHFAAYTYLKPLLQQV
FVLSPSAISLQLLAYGAIGLLGTFLGERLAERSLRATFILITAMLAAILIVSPFLSGIAGATLMVMVWGLAFGAVPVCAT
NWMFAAVPQAPEAGQALLVCVIQIALASGALLGGEVVDWQGVSSAMLFGGALTLSAALVFGLTLRSGMIGVKQS

Specific function: Regulates the expression of oprD which encodes the imipenem-specific porin [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ywfA [H]

Homologues:

Organism=Escherichia coli, GI145693198, Length=370, Percent_Identity=32.972972972973, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1787947, Length=307, Percent_Identity=30.2931596091205, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787808, Length=239, Percent_Identity=29.7071129707113, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786595, Length=276, Percent_Identity=25.7246376811594, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 40700; Mature: 40700

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNNNDKPAPSAWLAIFSLTVACFVMVTTEFLPIGLLTNIAPSLDVSTGRAGLMVTVPGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHH
IAAIAAPALSLAAGRLDRRLLMLALSVLLAISNLVSALAVNFPMMLLGRVLLGICVGGFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AFAANYGRHLVPEASQGRATALILSGISVGAVCGVPAGALIGDLFGWRAAFFGSAVLAVG
HHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLLAQLRLLTSVPPTRPVTARDLLLPLRLPMARTGLIAIVLLFIGHFAAYTYLKPLLQQV
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLSPSAISLQLLAYGAIGLLGTFLGERLAERSLRATFILITAMLAAILIVSPFLSGIAG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATLMVMVWGLAFGAVPVCATNWMFAAVPQAPEAGQALLVCVIQIALASGALLGGEVVDWQ
HHHHHHHHHHHHHCHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEECCC
GVSSAMLFGGALTLSAALVFGLTLRSGMIGVKQS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLNNNDKPAPSAWLAIFSLTVACFVMVTTEFLPIGLLTNIAPSLDVSTGRAGLMVTVPGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHH
IAAIAAPALSLAAGRLDRRLLMLALSVLLAISNLVSALAVNFPMMLLGRVLLGICVGGFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AFAANYGRHLVPEASQGRATALILSGISVGAVCGVPAGALIGDLFGWRAAFFGSAVLAVG
HHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLLAQLRLLTSVPPTRPVTARDLLLPLRLPMARTGLIAIVLLFIGHFAAYTYLKPLLQQV
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLSPSAISLQLLAYGAIGLLGTFLGERLAERSLRATFILITAMLAAILIVSPFLSGIAG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATLMVMVWGLAFGAVPVCATNWMFAAVPQAPEAGQALLVCVIQIALASGALLGGEVVDWQ
HHHHHHHHHHHHHCHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEECCC
GVSSAMLFGGALTLSAALVFGLTLRSGMIGVKQS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1427017; 10984043 [H]