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The map label for this gene is tolR [H]

Identifier: 157369520

GI number: 157369520

Start: 1403819

End: 1404247

Strand: Direct

Name: tolR [H]

Synonym: Spro_1277

Alternate gene names: 157369520

Gene position: 1403819-1404247 (Clockwise)

Preceding gene: 157369519

Following gene: 157369521

Centisome position: 25.76

GC content: 55.71

Gene sequence:

>429_bases
ATGGCGAGAGTTCGTGGACGTAATCGGCGCGAGCTGAAGTCCGAAATTAACATCGTTCCGTTGCTCGACGTGTTGCTGGT
GCTGTTGCTGATCTTTATGGCAACCGCACCGATCATCACCCAGAGCGTTGAGGTTGATCTGCCGGACGCCACCGATTCCA
AAGCGGTTTCCAGCAGTGATAATCCACCGGTGATCCTCGAGGTTTCCGGCGTGGGCCAATACACCATGGTGGTGGATCAC
GACCGCATGGAACTGTTGCCGCCGGAGCAGGTTGCAGCCGAAGCCAAGTCGCGTTTGGCGGCCAACCCCAAGACGGTCTT
TTTGATCGGTGGGGCGAAGGAAGTTCCGTACGATGAGATTATCAAGGCATTGAATATTCTCCATCAGGCGGGCGTCACTT
CCGTGGGGTTGATGACCCAGCCAATTTGA

Upstream 100 bases:

>100_bases
CAACAAGCTTGAGCAGAATTACGACAACTTTATGGAAGAGTTCACCGCTATTCTGCATCGTCAGGCCTTCTCCAGCGACA
GCAAATAAGTAGGAGGTAGC

Downstream 100 bases:

>100_bases
CCCTAAGGTCAGTGGCAACCCGGTTCCTGCGCTGCGGTGCAGGAACCCCGTATAAGCAACACCAGTTTTTGGGAATCTAT
TTTGGTAAAGGCAACTGAGC

Product: colicin uptake protein TolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MARVRGRNRRELKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATDSKAVSSSDNPPVILEVSGVGQYTMVVDH
DRMELLPPEQVAAEAKSRLAANPKTVFLIGGAKEVPYDEIIKALNILHQAGVTSVGLMTQPI

Sequences:

>Translated_142_residues
MARVRGRNRRELKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATDSKAVSSSDNPPVILEVSGVGQYTMVVDH
DRMELLPPEQVAAEAKSRLAANPKTVFLIGGAKEVPYDEIIKALNILHQAGVTSVGLMTQPI
>Mature_141_residues
ARVRGRNRRELKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATDSKAVSSSDNPPVILEVSGVGQYTMVVDHD
RMELLPPEQVAAEAKSRLAANPKTVFLIGGAKEVPYDEIIKALNILHQAGVTSVGLMTQPI

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3, And K). [C]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1786959, Length=132, Percent_Identity=84.8484848484848, Blast_Score=201, Evalue=1e-53,
Organism=Escherichia coli, GI1789380, Length=131, Percent_Identity=32.824427480916, Blast_Score=59, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014168
- InterPro:   IPR003400 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 15365; Mature: 15234

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVRGRNRRELKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATDSKAVSSSD
CCCCCCCCHHHHHHHCCEECHHHHHHHHHHHHHHHCHHHHCCEEEECCCCCCCCCCCCCC
NPPVILEVSGVGQYTMVVDHDRMELLPPEQVAAEAKSRLAANPKTVFLIGGAKEVPYDEI
CCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
IKALNILHQAGVTSVGLMTQPI
HHHHHHHHHCCCCCCCCEECCC
>Mature Secondary Structure 
ARVRGRNRRELKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATDSKAVSSSD
CCCCCCCHHHHHHHCCEECHHHHHHHHHHHHHHHCHHHHCCEEEECCCCCCCCCCCCCC
NPPVILEVSGVGQYTMVVDHDRMELLPPEQVAAEAKSRLAANPKTVFLIGGAKEVPYDEI
CCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
IKALNILHQAGVTSVGLMTQPI
HHHHHHHHHCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]