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The map label for this gene is gltK [H]

Identifier: 157369455

GI number: 157369455

Start: 1328820

End: 1329494

Strand: Reverse

Name: gltK [H]

Synonym: Spro_1212

Alternate gene names: 157369455

Gene position: 1329494-1328820 (Counterclockwise)

Preceding gene: 157369456

Following gene: 157369454

Centisome position: 24.4

GC content: 54.96

Gene sequence:

>675_bases
ATGTACGAATTTGACTGGGCATCAATTGTCCCAAGCTTCCCTTACCTGCTGCAAGGTCTGTTGATCACGCTGAAGATCAC
CGTGACCGCTATCGTCTTCGGTATCCTTTGGGGCACCATTCTGGCCGTCATGCGTCTGTCGCCATTCAAGCCCATCAGCT
GGTTTGCCGCGCTGTACGTCAACCTGTTCCGTTCGGTGCCGCTGGTGATGGTGCTGCTGTGGTTCTATCTGGTGGTTCCA
AGCTTATTACAACAAGTTCTGGGGCTGTCGCCGAAAACCGATATTCGCCTGATCTCGGCTATGGTAGCCTTTTCCCTGTT
TGAAGCGGCCTATTACTCGGAAATCATCCGCGCCGGTATTATCAGCATCTCGCGCGGCCAGTCTTCCGCCGCGCTGGCGC
TGGGCATGAGCCACTGGCAGTCAATGAAACTGGTTATTTTGCCGCAGGCGTTCCGCGCCATGGTGCCACTGCTGCTGACT
CAGGGCATCGTACTGTTCCAGGATACTTCTCTGGTCTACGTACTGAGCCTGGCTGACTTCTTCCGTACCGCCTCAACCAT
CGGCGAGCGCGACGGCACCCAGGTTGAAATGATCCTGTTCGCCGGCTTTGTCTACTTTGTTATCAGTCTCGCCGCCTCGG
CGCTGGTAAGCTATTTGAAGAAAAGGACTGTTTGA

Upstream 100 bases:

>100_bases
CGATTACGCTGGCCTACATCGCCATCAACGCCGTGATCATGCTGTTTATGCGACTGGTAGAGCGAAAAGTGCAGTTGCCC
GGCAATCTGGGGAGTAAATA

Downstream 100 bases:

>100_bases
TGATATCCCTGAAAAATGTTTCTAAGTGGTACGGTCACTTTCAGGTTCTGACCGATTGCACCACCGAAGTCAAAAAAGGT
GAGGTGGTGGTAGTCTGCGG

Product: polar amino acid ABC transporter inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MYEFDWASIVPSFPYLLQGLLITLKITVTAIVFGILWGTILAVMRLSPFKPISWFAALYVNLFRSVPLVMVLLWFYLVVP
SLLQQVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMSHWQSMKLVILPQAFRAMVPLLLT
QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKRTV

Sequences:

>Translated_224_residues
MYEFDWASIVPSFPYLLQGLLITLKITVTAIVFGILWGTILAVMRLSPFKPISWFAALYVNLFRSVPLVMVLLWFYLVVP
SLLQQVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMSHWQSMKLVILPQAFRAMVPLLLT
QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKRTV
>Mature_224_residues
MYEFDWASIVPSFPYLLQGLLITLKITVTAIVFGILWGTILAVMRLSPFKPISWFAALYVNLFRSVPLVMVLLWFYLVVP
SLLQQVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMSHWQSMKLVILPQAFRAMVPLLLT
QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKRTV

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=223, Percent_Identity=87.8923766816144, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1788226, Length=214, Percent_Identity=37.8504672897196, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI87082239, Length=207, Percent_Identity=32.3671497584541, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787030, Length=220, Percent_Identity=30.4545454545455, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786874, Length=170, Percent_Identity=32.3529411764706, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788646, Length=211, Percent_Identity=24.6445497630332, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1787087, Length=220, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI48994930, Length=122, Percent_Identity=33.6065573770492, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788645, Length=224, Percent_Identity=26.3392857142857, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24936; Mature: 24936

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEFDWASIVPSFPYLLQGLLITLKITVTAIVFGILWGTILAVMRLSPFKPISWFAALYV
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
NLFRSVPLVMVLLWFYLVVPSLLQQVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISISRGQSSAALALGMSHWQSMKLVILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLADF
HHHCCCCCHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHH
FRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKRTV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYEFDWASIVPSFPYLLQGLLITLKITVTAIVFGILWGTILAVMRLSPFKPISWFAALYV
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
NLFRSVPLVMVLLWFYLVVPSLLQQVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISISRGQSSAALALGMSHWQSMKLVILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLADF
HHHCCCCCHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHH
FRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKRTV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]