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The map label for this gene is feaR [H]

Identifier: 157369227

GI number: 157369227

Start: 1088084

End: 1088992

Strand: Direct

Name: feaR [H]

Synonym: Spro_0984

Alternate gene names: 157369227

Gene position: 1088084-1088992 (Clockwise)

Preceding gene: 157369226

Following gene: 157369231

Centisome position: 19.97

GC content: 59.08

Gene sequence:

>909_bases
ATGGCAATTTCCGCGCAGGTCAGGGAGGCCGGTTTCGAGGAGTGGTTGGCGAAAATCAACTCCGCCTGCGGCCGCTTTTG
CGCCAGGACATTGGGGCCTGGCTTTAGCGGGGCTATGCAGGAATTCCGTGCCCACGCGCTGCGCCTGAGCGTGGTGGATG
CCGCTCAGACCCGGTTGTATCGTACCCAACAGGAGATTGCCCGCAGCGACGGTTCGCACTTTTTCACGGTATTTCAGCTA
CGTGGCAGCTCATTGATGGAACAGGGCGATCGGCAGGCGGTGTTGTCCGCCGGTGACGTCACGCTAATCGACGCTTCGCG
CACCAGCAGCTTTACCTTTCAACAAGACTCCCGCCAAATTTCATTGCTGATGCCGCGCAGCTATCTTGAGCAGTCTGCGT
CCGATGTACAGTGCGTGCGGCGGCTGGATGCACAAAGCAGCGTGGTGCGCCTTAGCCGGCAACTGGTGCTGGGGTGCATG
CAAGACACACAGATGAGCGCTCCAGAGAGTGAGGCGATATTGAACGCGGTTGCGACGCTGTTGCGTCCGGCGCTGGTCGA
TCGCGTGGTGGGGGGAGACAGTCCTCCACGCAGCTTCAGCCGTACGCTGGCGTTTATCGATACGCATATTCAGTCGCCGC
AGTTACGGCCGGAGTGGATCGCCGATGAGCTTGGCGTTTCGGTGCGCAGTCTGTATCGGATGTTTGCTCGTCAGGGGCTG
GTGGTGGCGCAATATATCAAGCACCGCCGTCTGGATTTGTGTGCGCAGGCGTTACGCAGCGCCCCGGAGCGACAGAAACT
GGCCACTATCAGTTATGACTGGGGTTTTGCCGATCACAGCCACTTTTCCACCGCCTTCAAAAGCCGTTTTGGCGTTTCGC
CGAGCGAATATCGCAAGCAGTATCAATAG

Upstream 100 bases:

>100_bases
AGATCCCGGTTCCGGCATTGCTTGTATGTTATCGGGTTGTTATGTTGATTTTCTGTTCAACGCCGACAGCGTTTGTCGCT
GATGTGTGAAGGGGTAAAGC

Downstream 100 bases:

>100_bases
CGCCTTCTACGGCGCTATTGATGATGAAGGCGCTCTTTAGTAACGAATGCACACCGATTTGGATTCGGTATAGGCATCCA
GCCAGTCCGGGCCGAAGTCG

Product: DNA-binding transcriptional activator FeaR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MAISAQVREAGFEEWLAKINSACGRFCARTLGPGFSGAMQEFRAHALRLSVVDAAQTRLYRTQQEIARSDGSHFFTVFQL
RGSSLMEQGDRQAVLSAGDVTLIDASRTSSFTFQQDSRQISLLMPRSYLEQSASDVQCVRRLDAQSSVVRLSRQLVLGCM
QDTQMSAPESEAILNAVATLLRPALVDRVVGGDSPPRSFSRTLAFIDTHIQSPQLRPEWIADELGVSVRSLYRMFARQGL
VVAQYIKHRRLDLCAQALRSAPERQKLATISYDWGFADHSHFSTAFKSRFGVSPSEYRKQYQ

Sequences:

>Translated_302_residues
MAISAQVREAGFEEWLAKINSACGRFCARTLGPGFSGAMQEFRAHALRLSVVDAAQTRLYRTQQEIARSDGSHFFTVFQL
RGSSLMEQGDRQAVLSAGDVTLIDASRTSSFTFQQDSRQISLLMPRSYLEQSASDVQCVRRLDAQSSVVRLSRQLVLGCM
QDTQMSAPESEAILNAVATLLRPALVDRVVGGDSPPRSFSRTLAFIDTHIQSPQLRPEWIADELGVSVRSLYRMFARQGL
VVAQYIKHRRLDLCAQALRSAPERQKLATISYDWGFADHSHFSTAFKSRFGVSPSEYRKQYQ
>Mature_301_residues
AISAQVREAGFEEWLAKINSACGRFCARTLGPGFSGAMQEFRAHALRLSVVDAAQTRLYRTQQEIARSDGSHFFTVFQLR
GSSLMEQGDRQAVLSAGDVTLIDASRTSSFTFQQDSRQISLLMPRSYLEQSASDVQCVRRLDAQSSVVRLSRQLVLGCMQ
DTQMSAPESEAILNAVATLLRPALVDRVVGGDSPPRSFSRTLAFIDTHIQSPQLRPEWIADELGVSVRSLYRMFARQGLV
VAQYIKHRRLDLCAQALRSAPERQKLATISYDWGFADHSHFSTAFKSRFGVSPSEYRKQYQ

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=292, Percent_Identity=48.972602739726, Blast_Score=284, Evalue=5e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33795; Mature: 33664

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISAQVREAGFEEWLAKINSACGRFCARTLGPGFSGAMQEFRAHALRLSVVDAAQTRLY
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RTQQEIARSDGSHFFTVFQLRGSSLMEQGDRQAVLSAGDVTLIDASRTSSFTFQQDSRQI
HHHHHHHHCCCCCEEEEEEECCHHHHHCCCHHHHHCCCCEEEEECCCCCCEEECCCCCEE
SLLMPRSYLEQSASDVQCVRRLDAQSSVVRLSRQLVLGCMQDTQMSAPESEAILNAVATL
EEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LRPALVDRVVGGDSPPRSFSRTLAFIDTHIQSPQLRPEWIADELGVSVRSLYRMFARQGL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
VVAQYIKHRRLDLCAQALRSAPERQKLATISYDWGFADHSHFSTAFKSRFGVSPSEYRKQ
HHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHC
YQ
CC
>Mature Secondary Structure 
AISAQVREAGFEEWLAKINSACGRFCARTLGPGFSGAMQEFRAHALRLSVVDAAQTRLY
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RTQQEIARSDGSHFFTVFQLRGSSLMEQGDRQAVLSAGDVTLIDASRTSSFTFQQDSRQI
HHHHHHHHCCCCCEEEEEEECCHHHHHCCCHHHHHCCCCEEEEECCCCCCEEECCCCCEE
SLLMPRSYLEQSASDVQCVRRLDAQSSVVRLSRQLVLGCMQDTQMSAPESEAILNAVATL
EEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LRPALVDRVVGGDSPPRSFSRTLAFIDTHIQSPQLRPEWIADELGVSVRSLYRMFARQGL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
VVAQYIKHRRLDLCAQALRSAPERQKLATISYDWGFADHSHFSTAFKSRFGVSPSEYRKQ
HHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHC
YQ
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]