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The map label for this gene is mtnD

Identifier: 157369189

GI number: 157369189

Start: 1041891

End: 1042433

Strand: Direct

Name: mtnD

Synonym: Spro_0944

Alternate gene names: 157369189

Gene position: 1041891-1042433 (Clockwise)

Preceding gene: 157369188

Following gene: 157369191

Centisome position: 19.12

GC content: 57.64

Gene sequence:

>543_bases
ATGAGTGGATTGACCATTTTCAGCGATCAAGAGCCGCAACAGCCGCTGTGGCAGAGCCGTGACGCGCAGGCCATTGGGCA
GCAACTGGCACAGATTGGCGTACGTTTTGAACGCTGGCAGGCGGATCGTGAACTGGGTGAAAACCCGGATCCGGCCGTCG
TGATCGCCGCCTATCAGCATCAGATCGACCGGCTGGTGGCGGAGAAGGGCTACCAGAGTTGGGATGTGATCAGCATGCGT
CCGGATAATGCCCAGCGCGAAGTGTTGCGCAGCAAGTTTCTGTCCGAGCATACCCACGGCGAAGATGAAGTGCGTTTCTT
TGTCGAGGGGGCCGGGCTGTTCTGCCTGCATCTGGATGGCAAGATCTTCCAGATCCTGTGTGAGAAGAACGATCTGATCT
CGGTACCGGCCAATACCCGTCATTGGTTCGATATGGGCTCAGCACCGAATTTCACTGCGATCCGCGTGTTTGATAACCCG
GAAGGCTGGGTGGCGCATTTCACCGGCGATAACATCGCCGATGCCTACCCGCGTCTCGACTGA

Upstream 100 bases:

>100_bases
GTTGGCATACCTGCCAACTGATCCGCGATGAAGCCGATAGCCAAAGCCAGCATCCGCAGGTTAACCGTTTTGATCAAATC
GATTTAGGGGAGTTTGCCTC

Downstream 100 bases:

>100_bases
GCGCTATAACGCGGGCTTTAACCCAACGCCCGCTGAAAAATCCCTTCACTGACCTGCTGTGGCGTGATCACGCCGCTGTC
GAAGACCCAACCGCTAATCA

Product: acireductone dioxygenase ARD

Products: NA

Alternate protein names: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; DHK-MTPene dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); ARD'; Fe-ARD; Acireductone dioxygenase (Ni(2+)-requiring); ARD; Ni-ARD

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MSGLTIFSDQEPQQPLWQSRDAQAIGQQLAQIGVRFERWQADRELGENPDPAVVIAAYQHQIDRLVAEKGYQSWDVISMR
PDNAQREVLRSKFLSEHTHGEDEVRFFVEGAGLFCLHLDGKIFQILCEKNDLISVPANTRHWFDMGSAPNFTAIRVFDNP
EGWVAHFTGDNIADAYPRLD

Sequences:

>Translated_180_residues
MSGLTIFSDQEPQQPLWQSRDAQAIGQQLAQIGVRFERWQADRELGENPDPAVVIAAYQHQIDRLVAEKGYQSWDVISMR
PDNAQREVLRSKFLSEHTHGEDEVRFFVEGAGLFCLHLDGKIFQILCEKNDLISVPANTRHWFDMGSAPNFTAIRVFDNP
EGWVAHFTGDNIADAYPRLD
>Mature_179_residues
SGLTIFSDQEPQQPLWQSRDAQAIGQQLAQIGVRFERWQADRELGENPDPAVVIAAYQHQIDRLVAEKGYQSWDVISMRP
DNAQREVLRSKFLSEHTHGEDEVRFFVEGAGLFCLHLDGKIFQILCEKNDLISVPANTRHWFDMGSAPNFTAIRVFDNPE
GWVAHFTGDNIADAYPRLD

Specific function: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- me

COG id: COG1791

COG function: function code S; Uncharacterized conserved protein, contains double-stranded beta-helix domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acireductone dioxygenase (ARD) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTND_SERP5 (A8GAB0)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477178.1
- ProteinModelPortal:   A8GAB0
- SMR:   A8GAB0
- STRING:   A8GAB0
- GeneID:   5605063
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0944
- eggNOG:   COG1791
- HOGENOM:   HBG660685
- OMA:   CEKNDLI
- ProtClustDB:   CLSK928049
- BioCyc:   SPRO399741:SPRO_0944-MONOMER
- HAMAP:   MF_01682
- InterPro:   IPR004313
- InterPro:   IPR011051
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- PANTHER:   PTHR23418

Pfam domain/function: PF03079 ARD; SSF51182 RmlC_like_cupin

EC number: =1.13.11.54; =1.13.11.53

Molecular weight: Translated: 20527; Mature: 20396

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLTIFSDQEPQQPLWQSRDAQAIGQQLAQIGVRFERWQADRELGENPDPAVVIAAYQH
CCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEHHHHH
QIDRLVAEKGYQSWDVISMRPDNAQREVLRSKFLSEHTHGEDEVRFFVEGAGLFCLHLDG
HHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECC
KIFQILCEKNDLISVPANTRHWFDMGSAPNFTAIRVFDNPEGWVAHFTGDNIADAYPRLD
CEEEEEECCCCEEECCCCCCEEEECCCCCCEEEEEEEECCCCEEEEECCCCHHCCCCCCC
>Mature Secondary Structure 
SGLTIFSDQEPQQPLWQSRDAQAIGQQLAQIGVRFERWQADRELGENPDPAVVIAAYQH
CCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEHHHHH
QIDRLVAEKGYQSWDVISMRPDNAQREVLRSKFLSEHTHGEDEVRFFVEGAGLFCLHLDG
HHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECC
KIFQILCEKNDLISVPANTRHWFDMGSAPNFTAIRVFDNPEGWVAHFTGDNIADAYPRLD
CEEEEEECCCCEEECCCCCCEEEECCCCCCEEEEEEEECCCCEEEEECCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA