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The map label for this gene is ywrD [H]

Identifier: 157369175

GI number: 157369175

Start: 1029458

End: 1031044

Strand: Reverse

Name: ywrD [H]

Synonym: Spro_0930

Alternate gene names: 157369175

Gene position: 1031044-1029458 (Counterclockwise)

Preceding gene: 157369185

Following gene: 157369174

Centisome position: 18.92

GC content: 63.83

Gene sequence:

>1587_bases
ATGATTAACAGCAACACCGCGCCATTGGGCATGGCCGTCACGCCGCACCACCTCGCCAGCGAAAGCGCACTGGCGATACT
GCGCAAAGGCGGCAACGCGATTGAAGCCATGGTCGCCGCCGCCGCTACCATCGCCGTGGTCTACCCACACATGAACGGCC
TGGGTGGCGATGGGTTCTGGCTGATCGTGCCGCCGCAGGGTGATCCGGTGGCCATCGACGCCAGCGGCGCAGCCGGATCG
CTGGCCACGCTGGATTTTTACGCCGGGGAAAGTCACATTCCCCATCGGGGGCCAAAAGCCGCGCTGACCGTCGCCGGCAC
CGTCGGGGGCTGGCAGGAAGCACTGGATTACTCCGCTGAACTGGGCGGCCAGCAGTTGCCGTTGCCACGCCTGCTGGCTG
ATGCGATTCGCTACGCTGCAGACGGTATTCCGGTCACCGCCTCGCAGGAGGCGGCTACCCGCAGCAAATATCATGAGCTG
GCAGATCAGGAGCATTTTGCCCGCACCTACCTGCCGCACGGTGAAATTCCTCACGCCGGACAGCGTTTCTGCCAGCCGCA
GTTGGCGGAGACTCTGATTACCCTGGCCGAACAGGGGTTGGACAGCTTCTATCGCGGCCGATTGGCAGAGAGCATGGCGG
CGGATATGGCCAGGCTGGGCATGCCGCTCACTGCGCAGGATCTGGCGGATTATCGGCCGCGCCGCCGCACGCCGCTGCGG
CTGGAGCATCAGAAAGGCGAGATCTTTAACCTGACGCCGCCGACTCAGGGCCTGGTGTCACTGGCGATCCTCGGGCTGAC
CGACCGTCTGCCACTTGCCAGCCGCAGCGAAGGCGCGGTGGTACATGGCATCGTCGAGGCCACCAAACTGGCTTTCGGCC
TGCGTGACCAATTCATCACCGATCCGCGTCAGATGACTCAGGATCCACAGGCATTGTTGACAGCCGAACACCTGGACGCG
CTGGCCAGGCGCATCGATCCTGAACAGGCCGCCTCCTGGGGCAAAGGCAAAGGGCCGGGCGATACCGTGTGGATGGGGAC
GATGGACAGCAGCGGTCTGGCGGTGTCCTTTATTCAAAGTATCTATCACGAATTCGGCAGCGGCGTGGTGCTGCCGCAAA
GTGGCGTGCTGTGGCAAAACCGTGGCGCGTCTTTCAGCCTGGATGCCGCGCACCTGCTGGCATTGGCGCCGGGTAAACAA
CCCTTCCATACCTTGAACCCGGCAGCGGCACGCCTGTATGACGGGCGTACCCTGGTATACGGCTCGATGGGCGGTGACGG
CCAGCCGCAAACCCAGGCAGCGGTGTTTGTTCGCCATGTGGTGCAGGGGCTGCCGCTGCAACAGGCGATCAGCGCGCCGC
GCTGGCTGCTCGGCCGCACCTGGGGTGAAAGCTCCGACTCATTAAAACTGGAGGGGCGTTTTAGTCAGGAAACCCTGGCC
TACCTGCGTCAACGCGGCCACGAGGTAGAACTCTTAGCGGATTTCAGCGAGGCGGTCGGCCACGCCGGCGCCATTGTTCG
CCATACTAACGGCATGCTCGAAGGCGCTTTTGATCCGCGCAGCAACGGCAGCGCCGCCGGCTTCTAG

Upstream 100 bases:

>100_bases
CAATCCACCCGCTGGCAAGCGATTATTGTCCTGGCAGAAAACATGGAACGTCTCTTGCTTGTGTTTGAGGCAGACGCTGA
CCTCAAACAAGGGCCAAGAA

Downstream 100 bases:

>100_bases
CCGCTCTTTCAATAAGGGGATCCCCATGAACCATCCACCTGCCACCGACTGGGCGGCTTATATCAGCCAGATGGAAAACA
TACTGGCCCTGCAGCTCAAT

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MINSNTAPLGMAVTPHHLASESALAILRKGGNAIEAMVAAAATIAVVYPHMNGLGGDGFWLIVPPQGDPVAIDASGAAGS
LATLDFYAGESHIPHRGPKAALTVAGTVGGWQEALDYSAELGGQQLPLPRLLADAIRYAADGIPVTASQEAATRSKYHEL
ADQEHFARTYLPHGEIPHAGQRFCQPQLAETLITLAEQGLDSFYRGRLAESMAADMARLGMPLTAQDLADYRPRRRTPLR
LEHQKGEIFNLTPPTQGLVSLAILGLTDRLPLASRSEGAVVHGIVEATKLAFGLRDQFITDPRQMTQDPQALLTAEHLDA
LARRIDPEQAASWGKGKGPGDTVWMGTMDSSGLAVSFIQSIYHEFGSGVVLPQSGVLWQNRGASFSLDAAHLLALAPGKQ
PFHTLNPAAARLYDGRTLVYGSMGGDGQPQTQAAVFVRHVVQGLPLQQAISAPRWLLGRTWGESSDSLKLEGRFSQETLA
YLRQRGHEVELLADFSEAVGHAGAIVRHTNGMLEGAFDPRSNGSAAGF

Sequences:

>Translated_528_residues
MINSNTAPLGMAVTPHHLASESALAILRKGGNAIEAMVAAAATIAVVYPHMNGLGGDGFWLIVPPQGDPVAIDASGAAGS
LATLDFYAGESHIPHRGPKAALTVAGTVGGWQEALDYSAELGGQQLPLPRLLADAIRYAADGIPVTASQEAATRSKYHEL
ADQEHFARTYLPHGEIPHAGQRFCQPQLAETLITLAEQGLDSFYRGRLAESMAADMARLGMPLTAQDLADYRPRRRTPLR
LEHQKGEIFNLTPPTQGLVSLAILGLTDRLPLASRSEGAVVHGIVEATKLAFGLRDQFITDPRQMTQDPQALLTAEHLDA
LARRIDPEQAASWGKGKGPGDTVWMGTMDSSGLAVSFIQSIYHEFGSGVVLPQSGVLWQNRGASFSLDAAHLLALAPGKQ
PFHTLNPAAARLYDGRTLVYGSMGGDGQPQTQAAVFVRHVVQGLPLQQAISAPRWLLGRTWGESSDSLKLEGRFSQETLA
YLRQRGHEVELLADFSEAVGHAGAIVRHTNGMLEGAFDPRSNGSAAGF
>Mature_528_residues
MINSNTAPLGMAVTPHHLASESALAILRKGGNAIEAMVAAAATIAVVYPHMNGLGGDGFWLIVPPQGDPVAIDASGAAGS
LATLDFYAGESHIPHRGPKAALTVAGTVGGWQEALDYSAELGGQQLPLPRLLADAIRYAADGIPVTASQEAATRSKYHEL
ADQEHFARTYLPHGEIPHAGQRFCQPQLAETLITLAEQGLDSFYRGRLAESMAADMARLGMPLTAQDLADYRPRRRTPLR
LEHQKGEIFNLTPPTQGLVSLAILGLTDRLPLASRSEGAVVHGIVEATKLAFGLRDQFITDPRQMTQDPQALLTAEHLDA
LARRIDPEQAASWGKGKGPGDTVWMGTMDSSGLAVSFIQSIYHEFGSGVVLPQSGVLWQNRGASFSLDAAHLLALAPGKQ
PFHTLNPAAARLYDGRTLVYGSMGGDGQPQTQAAVFVRHVVQGLPLQQAISAPRWLLGRTWGESSDSLKLEGRFSQETLA
YLRQRGHEVELLADFSEAVGHAGAIVRHTNGMLEGAFDPRSNGSAAGF

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=536, Percent_Identity=27.2388059701493, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI73915090, Length=536, Percent_Identity=27.2388059701493, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI73915096, Length=536, Percent_Identity=27.2388059701493, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI73915094, Length=536, Percent_Identity=27.2388059701493, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI113429324, Length=538, Percent_Identity=26.3940520446097, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI113429326, Length=541, Percent_Identity=25.8780036968577, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI109148539, Length=544, Percent_Identity=27.2058823529412, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI153266885, Length=570, Percent_Identity=25.6140350877193, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI153266901, Length=571, Percent_Identity=25.569176882662, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI153266907, Length=554, Percent_Identity=26.3537906137184, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI1789856, Length=548, Percent_Identity=29.9270072992701, Blast_Score=202, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI212646519, Length=531, Percent_Identity=24.6704331450094, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI72000294, Length=531, Percent_Identity=24.6704331450094, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17542894, Length=511, Percent_Identity=25.6360078277886, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17506189, Length=533, Percent_Identity=24.015009380863, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193208247, Length=487, Percent_Identity=24.6406570841889, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193208245, Length=487, Percent_Identity=24.6406570841889, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI18859893, Length=536, Percent_Identity=26.1194029850746, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI161077878, Length=552, Percent_Identity=24.4565217391304, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45551474, Length=552, Percent_Identity=24.4565217391304, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24642670, Length=552, Percent_Identity=24.4565217391304, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24642666, Length=552, Percent_Identity=24.4565217391304, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI161077880, Length=552, Percent_Identity=24.4565217391304, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI161077496, Length=506, Percent_Identity=23.5177865612648, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 56289; Mature: 56289

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINSNTAPLGMAVTPHHLASESALAILRKGGNAIEAMVAAAATIAVVYPHMNGLGGDGFW
CCCCCCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCCCCCCCCEEE
LIVPPQGDPVAIDASGAAGSLATLDFYAGESHIPHRGPKAALTVAGTVGGWQEALDYSAE
EEECCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
LGGQQLPLPRLLADAIRYAADGIPVTASQEAATRSKYHELADQEHFARTYLPHGEIPHAG
CCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
QRFCQPQLAETLITLAEQGLDSFYRGRLAESMAADMARLGMPLTAQDLADYRPRRRTPLR
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCE
LEHQKGEIFNLTPPTQGLVSLAILGLTDRLPLASRSEGAVVHGIVEATKLAFGLRDQFIT
EECCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCC
DPRQMTQDPQALLTAEHLDALARRIDPEQAASWGKGKGPGDTVWMGTMDSSGLAVSFIQS
CHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHH
IYHEFGSGVVLPQSGVLWQNRGASFSLDAAHLLALAPGKQPFHTLNPAAARLYDGRTLVY
HHHHHCCCEEECCCCCEECCCCCCEECCHHHHEEECCCCCCCCCCCHHHHHHCCCCEEEE
GSMGGDGQPQTQAAVFVRHVVQGLPLQQAISAPRWLLGRTWGESSDSLKLEGRFSQETLA
ECCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCHHHHHCCCCCCCCCEEEECCCCHHHHH
YLRQRGHEVELLADFSEAVGHAGAIVRHTNGMLEGAFDPRSNGSAAGF
HHHHCCCEEEEEHHHHHHHHHCCEEEEECCCCEECCCCCCCCCCCCCC
>Mature Secondary Structure
MINSNTAPLGMAVTPHHLASESALAILRKGGNAIEAMVAAAATIAVVYPHMNGLGGDGFW
CCCCCCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCCCCCCCCEEE
LIVPPQGDPVAIDASGAAGSLATLDFYAGESHIPHRGPKAALTVAGTVGGWQEALDYSAE
EEECCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
LGGQQLPLPRLLADAIRYAADGIPVTASQEAATRSKYHELADQEHFARTYLPHGEIPHAG
CCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
QRFCQPQLAETLITLAEQGLDSFYRGRLAESMAADMARLGMPLTAQDLADYRPRRRTPLR
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCE
LEHQKGEIFNLTPPTQGLVSLAILGLTDRLPLASRSEGAVVHGIVEATKLAFGLRDQFIT
EECCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCC
DPRQMTQDPQALLTAEHLDALARRIDPEQAASWGKGKGPGDTVWMGTMDSSGLAVSFIQS
CHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHH
IYHEFGSGVVLPQSGVLWQNRGASFSLDAAHLLALAPGKQPFHTLNPAAARLYDGRTLVY
HHHHHCCCEEECCCCCEECCCCCCEECCHHHHEEECCCCCCCCCCCHHHHHHCCCCEEEE
GSMGGDGQPQTQAAVFVRHVVQGLPLQQAISAPRWLLGRTWGESSDSLKLEGRFSQETLA
ECCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCHHHHHCCCCCCCCCEEEECCCCHHHHH
YLRQRGHEVELLADFSEAVGHAGAIVRHTNGMLEGAFDPRSNGSAAGF
HHHHCCCEEEEEHHHHHHHHHCCEEEEECCCCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]