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The map label for this gene is yafC [H]

Identifier: 157369150

GI number: 157369150

Start: 1004125

End: 1005012

Strand: Reverse

Name: yafC [H]

Synonym: Spro_0905

Alternate gene names: 157369150

Gene position: 1005012-1004125 (Counterclockwise)

Preceding gene: 157369153

Following gene: 157369132

Centisome position: 18.44

GC content: 55.52

Gene sequence:

>888_bases
GTGAAAGCGAACTCTGATGAGTTAATTACCTTCGTCACCGTGGTGGAAAGCGGTAGCTTCAGCCGGGCAGCAGAACAACT
TGATCAGGCCAATTCGGTGGTCAGCCGCACGGTCAAGAAGCTGGAGGCCAAGTTGGGCGTAACGTTACTCAACCGCACTA
CGCGCCAGATCAGTCTGACGCAGGAAGGGGAAAACTATTTCCGTCAGGTACAGAAGGTACTGAGTGATATGGCTGCGGCA
GAGAATGCGCTGATGGAAAGCCGTCAGCGTCCGCAGGGGCTACTACGCGTCGATGCCGCCACCCCGGTGGTGCTGCACGT
ATTGACCCCGCTGGTGGCGGAATTTCGGGCACTGTATCCGGAAATGTCGTTGTCGCTGGTGTCGTCGGAGAACTTTATCA
ATCTGATTGAGCGCAAGGTGGATATCGCCATTCGCGTCGGTGAGCTGACCGACTCCAGCCTCAAGGCGCGCAAGCTGATG
ACCAGCTACCGGCGTGTGCTGGCCTCCCCCGCCTATTTGGCACAGTACGGTACGCCGCAAAAGGTAGAAGAATTAGAGCA
GCATAGCTGCATTGGTTTTAACGATTTGCCCAGCCTCAACCGCTGGCCACTGGCCTGTGCTGATGGCCGCCAGTTGGAAA
TTACACCTGGCCTGACCACCAACAGTGGGGAAACCCAGCGTCATCTGTGTCTGCACGGCAACGGTATTGCCTGCCTGTCG
AATTTTATGATTGATGCCGATATCGAGCGCGGCGATCTGGTGCCGATTTTGGTTGAAGAAACCCTGCCGGTAGCAATGCC
CGTTAACGCGGTGTATTACAGCGACAGTGCAGTCAGCAATCGCCTGCGCAGCTTTATCGATTTTATCAGTGAGCGATTGG
CGCAATAA

Upstream 100 bases:

>100_bases
TACTCCAAATAGCATTCAGGTTGATGGCGGCTATTATCGACCCGTGCTTAAATGATAAAAATGCTCAAAATATCAAATTA
ATTTTGCCAATGGAGCAACA

Downstream 100 bases:

>100_bases
AAAAGGCGCCCGTTTAGGCGCCTCAATGCGTATGCCGTCGAAAATCAATCCCAGTTAGGTGCCAGACCTTCCGGGCTGAC
CAAACGGCCATTGTTTTCCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKANSDELITFVTVVESGSFSRAAEQLDQANSVVSRTVKKLEAKLGVTLLNRTTRQISLTQEGENYFRQVQKVLSDMAAA
ENALMESRQRPQGLLRVDAATPVVLHVLTPLVAEFRALYPEMSLSLVSSENFINLIERKVDIAIRVGELTDSSLKARKLM
TSYRRVLASPAYLAQYGTPQKVEELEQHSCIGFNDLPSLNRWPLACADGRQLEITPGLTTNSGETQRHLCLHGNGIACLS
NFMIDADIERGDLVPILVEETLPVAMPVNAVYYSDSAVSNRLRSFIDFISERLAQ

Sequences:

>Translated_295_residues
MKANSDELITFVTVVESGSFSRAAEQLDQANSVVSRTVKKLEAKLGVTLLNRTTRQISLTQEGENYFRQVQKVLSDMAAA
ENALMESRQRPQGLLRVDAATPVVLHVLTPLVAEFRALYPEMSLSLVSSENFINLIERKVDIAIRVGELTDSSLKARKLM
TSYRRVLASPAYLAQYGTPQKVEELEQHSCIGFNDLPSLNRWPLACADGRQLEITPGLTTNSGETQRHLCLHGNGIACLS
NFMIDADIERGDLVPILVEETLPVAMPVNAVYYSDSAVSNRLRSFIDFISERLAQ
>Mature_295_residues
MKANSDELITFVTVVESGSFSRAAEQLDQANSVVSRTVKKLEAKLGVTLLNRTTRQISLTQEGENYFRQVQKVLSDMAAA
ENALMESRQRPQGLLRVDAATPVVLHVLTPLVAEFRALYPEMSLSLVSSENFINLIERKVDIAIRVGELTDSSLKARKLM
TSYRRVLASPAYLAQYGTPQKVEELEQHSCIGFNDLPSLNRWPLACADGRQLEITPGLTTNSGETQRHLCLHGNGIACLS
NFMIDADIERGDLVPILVEETLPVAMPVNAVYYSDSAVSNRLRSFIDFISERLAQ

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=64.8464163822526, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=33.1058020477816, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1789639, Length=287, Percent_Identity=33.1010452961672, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1789440, Length=295, Percent_Identity=28.135593220339, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=30.4498269896194, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=25.085910652921, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1787589, Length=273, Percent_Identity=27.1062271062271, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789173, Length=242, Percent_Identity=28.5123966942149, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI157672245, Length=154, Percent_Identity=31.1688311688312, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788481, Length=296, Percent_Identity=24.6621621621622, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082132, Length=292, Percent_Identity=26.027397260274, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788706, Length=176, Percent_Identity=26.1363636363636, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786448, Length=264, Percent_Identity=25.7575757575758, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786508, Length=74, Percent_Identity=41.8918918918919, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788748, Length=126, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786713, Length=83, Percent_Identity=38.5542168674699, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI145693105, Length=157, Percent_Identity=23.5668789808917, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32700; Mature: 32700

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKANSDELITFVTVVESGSFSRAAEQLDQANSVVSRTVKKLEAKLGVTLLNRTTRQISLT
CCCCCCHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEH
QEGENYFRQVQKVLSDMAAAENALMESRQRPQGLLRVDAATPVVLHVLTPLVAEFRALYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCH
EMSLSLVSSENFINLIERKVDIAIRVGELTDSSLKARKLMTSYRRVLASPAYLAQYGTPQ
HHHHHHHCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCH
KVEELEQHSCIGFNDLPSLNRWPLACADGRQLEITPGLTTNSGETQRHLCLHGNGIACLS
HHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHH
NFMIDADIERGDLVPILVEETLPVAMPVNAVYYSDSAVSNRLRSFIDFISERLAQ
HHHEECCCCCCCEEEEEECCCCCCEECCCEEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKANSDELITFVTVVESGSFSRAAEQLDQANSVVSRTVKKLEAKLGVTLLNRTTRQISLT
CCCCCCHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEH
QEGENYFRQVQKVLSDMAAAENALMESRQRPQGLLRVDAATPVVLHVLTPLVAEFRALYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCH
EMSLSLVSSENFINLIERKVDIAIRVGELTDSSLKARKLMTSYRRVLASPAYLAQYGTPQ
HHHHHHHCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCH
KVEELEQHSCIGFNDLPSLNRWPLACADGRQLEITPGLTTNSGETQRHLCLHGNGIACLS
HHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHH
NFMIDADIERGDLVPILVEETLPVAMPVNAVYYSDSAVSNRLRSFIDFISERLAQ
HHHEECCCCCCCEEEEEECCCCCCEECCCEEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]