Click here to switch to the map view.

The map label for this gene is luxS [H]

Identifier: 157369093

GI number: 157369093

Start: 945680

End: 946195

Strand: Direct

Name: luxS [H]

Synonym: Spro_0848

Alternate gene names: 157369093

Gene position: 945680-946195 (Clockwise)

Preceding gene: 157369092

Following gene: 157369096

Centisome position: 17.36

GC content: 54.26

Gene sequence:

>516_bases
ATGCCACTGCTGGATAGCTTCACCGTAGACCATACCCGCATGGCAGCCCCGGCTGTCCGCGTTGCGAAAACCATGAAAAC
TCCTCATGGCGATACCATCACCGTATTCGATCTGCGTTTTTGCCGCCCGAATCTGGAAGTGATGCCTGAGCGTGGCATCC
ATACGCTGGAACACCTGTTTGCCGGTTTTATGCGTGACCATCTGAATGGCCAGGGCGTTGAGATTATCGATATCTCCCCG
ATGGGATGCCGTACCGGCTTCTACATGAGCCTGATTGGCGTGCCGGAAGAGCAGCGTGTTGCCGATGCCTGGAAAGCGGC
AATGAGTGACGTGCTGAAAGTGACCGATCAGCGCAAAATTCCTGAGCTGAATGAGTTCCAGTGCGGTACTTACCACATGC
ACTCGCTGGAAGAAGCACAGGAAATCGCCAAGCACATCCTTGATCACGACGTGGTAGTGAATCACAACGAAGAGCTGGCG
CTGCCGAAAGAGAAGCTGCAGGAACTGCACATCTAG

Upstream 100 bases:

>100_bases
TGCGCGTCTTTCACATATTCAGACTCGCTGAGTTAGAAAAGGTTTCCTGGATAGATAAAAAAGTTTCGAAATAAATACTC
TTTTACGAGGAGGTAACGAA

Downstream 100 bases:

>100_bases
TTCGTCACCGGGCTACAGCGATAAAAAAAGACGCGATGTTCGCGTCTTTTTTCCTTTCTGGTGGGCGGTCAGTGTTGCTG
GACGCTGGACTGCAGCGATT

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MPLLDSFTVDHTRMAAPAVRVAKTMKTPHGDTITVFDLRFCRPNLEVMPERGIHTLEHLFAGFMRDHLNGQGVEIIDISP
MGCRTGFYMSLIGVPEEQRVADAWKAAMSDVLKVTDQRKIPELNEFQCGTYHMHSLEEAQEIAKHILDHDVVVNHNEELA
LPKEKLQELHI

Sequences:

>Translated_171_residues
MPLLDSFTVDHTRMAAPAVRVAKTMKTPHGDTITVFDLRFCRPNLEVMPERGIHTLEHLFAGFMRDHLNGQGVEIIDISP
MGCRTGFYMSLIGVPEEQRVADAWKAAMSDVLKVTDQRKIPELNEFQCGTYHMHSLEEAQEIAKHILDHDVVVNHNEELA
LPKEKLQELHI
>Mature_170_residues
PLLDSFTVDHTRMAAPAVRVAKTMKTPHGDTITVFDLRFCRPNLEVMPERGIHTLEHLFAGFMRDHLNGQGVEIIDISPM
GCRTGFYMSLIGVPEEQRVADAWKAAMSDVLKVTDQRKIPELNEFQCGTYHMHSLEEAQEIAKHILDHDVVVNHNEELAL
PKEKLQELHI

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=171, Percent_Identity=85.3801169590643, Blast_Score=310, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 19451; Mature: 19319

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTRMAAPAVRVAKTMKTPHGDTITVFDLRFCRPNLEVMPERGIHTLEHLF
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHH
AGFMRDHLNGQGVEIIDISPMGCRTGFYMSLIGVPEEQRVADAWKAAMSDVLKVTDQRKI
HHHHHHHCCCCCEEEEECCCCCCCCCHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
PELNEFQCGTYHMHSLEEAQEIAKHILDHDVVVNHNEELALPKEKLQELHI
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
PLLDSFTVDHTRMAAPAVRVAKTMKTPHGDTITVFDLRFCRPNLEVMPERGIHTLEHLF
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHH
AGFMRDHLNGQGVEIIDISPMGCRTGFYMSLIGVPEEQRVADAWKAAMSDVLKVTDQRKI
HHHHHHHCCCCCEEEEECCCCCCCCCHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
PELNEFQCGTYHMHSLEEAQEIAKHILDHDVVVNHNEELALPKEKLQELHI
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA