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The map label for this gene is deoD [H]

Identifier: 157368908

GI number: 157368908

Start: 729110

End: 729841

Strand: Direct

Name: deoD [H]

Synonym: Spro_0663

Alternate gene names: 157368908

Gene position: 729110-729841 (Clockwise)

Preceding gene: 157368907

Following gene: 157368909

Centisome position: 13.38

GC content: 55.05

Gene sequence:

>732_bases
ATGGCTACGCCGCATATTAATGCTGAAATGGGTGATTTCGCTGACGTAGTACTGATGCCGGGCGATCCGCTGCGTGCAAA
ATACATCGCGGAAACTTTCCTGGAAGGCGCGGTGGAAGTGAACAACGTGCGTGGCATGCTGGGCTTCACCGGGACCTACA
AAGGCCGCAAAATCTCCGTAATGGGTCACGGTATGGGTATCCCGTCCTGCTCCATTTATGCGCGTGAACTGATTGCCGAA
TTCGGCGTGAAGAAAATCATCCGTGTGGGTTCCTGCGGTGCGGTGCGTGACGATGTCAAACTGCGTGACGTGGTGATCGG
CATGGGTGCTTGCACCGATTCCAAAGTGAACCGTATGCGTTTCAAGGATCATGACTACGCGGCAATCGCCGACTTTGACA
TGGTGCGTAACGCAGTAGACGCAGCGGCAGCGCAGGGTATCCCGGCGCGCGTAGGCAACATCTTCTCCGCTGACCTGTTC
TACACGCCAGATCCGGACATGTTCCAGGTGATGAAGAAGTACGGCATCCTGGGTGTGGAAATGGAAGCGGCCGGTATCTA
CGGTGTGGCGGCTGAGCTGTACGAAGAGTTTGGCTGTAAGGCACTGACCATTTGTACCGTTTCTGACCACATCCTGCGTC
ACGAAGCGACCACCGCGGCAGAACGTCAGACCACCTTTAACGAAATGATCGTTATCGCGCTGGAATCTGTACTGCTGGGC
GACAAAGAGTAA

Upstream 100 bases:

>100_bases
CGATGGATTACGGCAAATCCATGTTCTAAGACTTTGTTAGTGCCGGGCGGTTGCCCGGCGTATTTTTTTATTCATGACGA
CGATTTAAAGGAAGACAATT

Downstream 100 bases:

>100_bases
TATCCAGCGGGCGCAGCACCTTGCTGCGCCCCTGTAGCAATCTATTCACCTTCCCTAAATCATTTCCTGAAAATACTTTA
CCTGACAGCTAATTAGCGCT

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEGAVEVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYARELIAE
FGVKKIIRVGSCGAVRDDVKLRDVVIGMGACTDSKVNRMRFKDHDYAAIADFDMVRNAVDAAAAQGIPARVGNIFSADLF
YTPDPDMFQVMKKYGILGVEMEAAGIYGVAAELYEEFGCKALTICTVSDHILRHEATTAAERQTTFNEMIVIALESVLLG
DKE

Sequences:

>Translated_243_residues
MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEGAVEVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYARELIAE
FGVKKIIRVGSCGAVRDDVKLRDVVIGMGACTDSKVNRMRFKDHDYAAIADFDMVRNAVDAAAAQGIPARVGNIFSADLF
YTPDPDMFQVMKKYGILGVEMEAAGIYGVAAELYEEFGCKALTICTVSDHILRHEATTAAERQTTFNEMIVIALESVLLG
DKE
>Mature_242_residues
ATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEGAVEVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYARELIAEF
GVKKIIRVGSCGAVRDDVKLRDVVIGMGACTDSKVNRMRFKDHDYAAIADFDMVRNAVDAAAAQGIPARVGNIFSADLFY
TPDPDMFQVMKKYGILGVEMEAAGIYGVAAELYEEFGCKALTICTVSDHILRHEATTAAERQTTFNEMIVIALESVLLGD
KE

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=243, Percent_Identity=87.6543209876543, Blast_Score=426, Evalue=1e-121,
Organism=Escherichia coli, GI1790265, Length=197, Percent_Identity=26.9035532994924, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 26389; Mature: 26258

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEGAVEVNNVRGMLGFTGTYKGRKISV
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEECCCCEEEEECCCCCCCEEEE
MGHGMGIPSCSIYARELIAEFGVKKIIRVGSCGAVRDDVKLRDVVIGMGACTDSKVNRMR
EECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHEEEECCCCCCCHHHHHC
FKDHDYAAIADFDMVRNAVDAAAAQGIPARVGNIFSADLFYTPDPDMFQVMKKYGILGVE
CCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHCCEEECCEEECCCCHHHHHHHHHCCEEEE
MEAAGIYGVAAELYEEFGCKALTICTVSDHILRHEATTAAERQTTFNEMIVIALESVLLG
EECCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DKE
CCC
>Mature Secondary Structure 
ATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEGAVEVNNVRGMLGFTGTYKGRKISV
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEECCCCEEEEECCCCCCCEEEE
MGHGMGIPSCSIYARELIAEFGVKKIIRVGSCGAVRDDVKLRDVVIGMGACTDSKVNRMR
EECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHEEEECCCCCCCHHHHHC
FKDHDYAAIADFDMVRNAVDAAAAQGIPARVGNIFSADLFYTPDPDMFQVMKKYGILGVE
CCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHCCEEECCEEECCCCHHHHHHHHHCCEEEE
MEAAGIYGVAAELYEEFGCKALTICTVSDHILRHEATTAAERQTTFNEMIVIALESVLLG
EECCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DKE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA