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The map label for this gene is lrrA [H]

Identifier: 157368853

GI number: 157368853

Start: 674788

End: 675717

Strand: Direct

Name: lrrA [H]

Synonym: Spro_0608

Alternate gene names: 157368853

Gene position: 674788-675717 (Clockwise)

Preceding gene: 157368849

Following gene: 157368854

Centisome position: 12.38

GC content: 53.12

Gene sequence:

>930_bases
ATGCAAGTAAAAAAGCGTGCGATTTTAGGGCAGTTGTCGGATATGGATCTGCGCTTACTGCGGGTGTTTAAGGTGGTGGT
CGACTGTGGTGGCATGAGCGCCGCCGAACTGGAGCTGAATATCAGCCTGTCGACCATCAGCAAGCATATCAAGGATCTGG
AGCAACGACTGGGGCTGACGCTTTGCCACCGCGGGCGCGAGGGGTTTGCGGTCACTGATGAAGGGCTGCTGATTTACCAG
GAAACCATTAACCTGCTGGCGGCCACCGAGGCTTTTCGCCGTGGTGTGGATGACGTACACCAGCGCCTGGGTGGGCAACT
GCACGTGGCGATATTTGACCATACCGTCAGCAACCCACAGGCGCATATTGGCCGGGCGATTGCCTTATTTAGCGAGCAGG
CGCCGGAAGTGTCTTTGCAAATGTATGTGGAGCCAATAAATACCATTGAGCGTGGCGTTATTGACGGACAATTTCAGATT
GGCATTATTCCCATGCACCGCAGTGCGGAAAGTTTATCTTATAGTTCATTATTTAGTGAGAGGATGTTCTTATATTGCGG
CACGCAGCATGAATTATTTTCCGCCGATCATGAAATGCTGAATTGGGATCTGTTGCACAATTATGCCTTTGCCGGATTAG
GTTATCACTCGCCGAATATGGAGCTGAGCCTGCAGCAGCATTTGCAGCGCAAGGCGACGGGCTTTGCCCAGGAGTCTATC
GCCACCTTAATTCTCTCCGGCAAGTACGTGGGTTTTCTGCCCGACCACTATGCGGCGTTTTTTGTCGCGCAGAATATGAT
GCGAGCGATCAAACCGGCGCTGTTTCGTTACCATTGCGAGTATTCCAGCGTGCTGCGGCGTTCACCCAGCCCACAGCGGG
TGGTCAAGCTGTTCCACGAATGCCTGCTGGCGACCCATGGAACAGCTTGA

Upstream 100 bases:

>100_bases
TTAATAATCTGACGTGTTAATGAATTGTTGCTTCAAATTGACTATGTTCCGCTTCTTCACTAATGTGAATAATCAAATAT
CGAAACTTACTTAAGGTTTT

Downstream 100 bases:

>100_bases
GGTTTACTGGTCTTTCTTCTTGCCAAAAATCTTGATCAGCACGCCGACCAGGATGCCGATGGCGATGCCGGTGAAAATCC
AACTGAATAGACCCGGGTTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MQVKKRAILGQLSDMDLRLLRVFKVVVDCGGMSAAELELNISLSTISKHIKDLEQRLGLTLCHRGREGFAVTDEGLLIYQ
ETINLLAATEAFRRGVDDVHQRLGGQLHVAIFDHTVSNPQAHIGRAIALFSEQAPEVSLQMYVEPINTIERGVIDGQFQI
GIIPMHRSAESLSYSSLFSERMFLYCGTQHELFSADHEMLNWDLLHNYAFAGLGYHSPNMELSLQQHLQRKATGFAQESI
ATLILSGKYVGFLPDHYAAFFVAQNMMRAIKPALFRYHCEYSSVLRRSPSPQRVVKLFHECLLATHGTA

Sequences:

>Translated_309_residues
MQVKKRAILGQLSDMDLRLLRVFKVVVDCGGMSAAELELNISLSTISKHIKDLEQRLGLTLCHRGREGFAVTDEGLLIYQ
ETINLLAATEAFRRGVDDVHQRLGGQLHVAIFDHTVSNPQAHIGRAIALFSEQAPEVSLQMYVEPINTIERGVIDGQFQI
GIIPMHRSAESLSYSSLFSERMFLYCGTQHELFSADHEMLNWDLLHNYAFAGLGYHSPNMELSLQQHLQRKATGFAQESI
ATLILSGKYVGFLPDHYAAFFVAQNMMRAIKPALFRYHCEYSSVLRRSPSPQRVVKLFHECLLATHGTA
>Mature_309_residues
MQVKKRAILGQLSDMDLRLLRVFKVVVDCGGMSAAELELNISLSTISKHIKDLEQRLGLTLCHRGREGFAVTDEGLLIYQ
ETINLLAATEAFRRGVDDVHQRLGGQLHVAIFDHTVSNPQAHIGRAIALFSEQAPEVSLQMYVEPINTIERGVIDGQFQI
GIIPMHRSAESLSYSSLFSERMFLYCGTQHELFSADHEMLNWDLLHNYAFAGLGYHSPNMELSLQQHLQRKATGFAQESI
ATLILSGKYVGFLPDHYAAFFVAQNMMRAIKPALFRYHCEYSSVLRRSPSPQRVVKLFHECLLATHGTA

Specific function: Transcriptional Activator For The Hut, Put And Ure Operons And Repressor For The Gdh And Gltb Operons In Response To Nitrogen Limitation. Negative Regulator Of Its Own Expression (By Similarity). [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788297, Length=255, Percent_Identity=27.4509803921569, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34759; Mature: 34759

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKKRAILGQLSDMDLRLLRVFKVVVDCGGMSAAELELNISLSTISKHIKDLEQRLGLT
CCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEHHHHHHHHHHHHHHHCHH
LCHRGREGFAVTDEGLLIYQETINLLAATEAFRRGVDDVHQRLGGQLHVAIFDHTVSNPQ
HHHCCCCCCEECCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEEEEECCCCCCH
AHIGRAIALFSEQAPEVSLQMYVEPINTIERGVIDGQFQIGIIPMHRSAESLSYSSLFSE
HHHHHHHHHHHCCCCCEEEEEEECHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHH
RMFLYCGTQHELFSADHEMLNWDLLHNYAFAGLGYHSPNMELSLQQHLQRKATGFAQESI
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHHHH
ATLILSGKYVGFLPDHYAAFFVAQNMMRAIKPALFRYHCEYSSVLRRSPSPQRVVKLFHE
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHH
CLLATHGTA
HHHHCCCCC
>Mature Secondary Structure
MQVKKRAILGQLSDMDLRLLRVFKVVVDCGGMSAAELELNISLSTISKHIKDLEQRLGLT
CCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEHHHHHHHHHHHHHHHCHH
LCHRGREGFAVTDEGLLIYQETINLLAATEAFRRGVDDVHQRLGGQLHVAIFDHTVSNPQ
HHHCCCCCCEECCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEEEEECCCCCCH
AHIGRAIALFSEQAPEVSLQMYVEPINTIERGVIDGQFQIGIIPMHRSAESLSYSSLFSE
HHHHHHHHHHHCCCCCEEEEEEECHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHH
RMFLYCGTQHELFSADHEMLNWDLLHNYAFAGLGYHSPNMELSLQQHLQRKATGFAQESI
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHHHH
ATLILSGKYVGFLPDHYAAFFVAQNMMRAIKPALFRYHCEYSSVLRRSPSPQRVVKLFHE
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHH
CLLATHGTA
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8661945 [H]